Cruises to Panama City
50 live cruises call at Panama City — 10 to 28 nights, departing 15 ports, across 8 lines. A NestCruise advisor narrows them to the one that fits.
CaribbeanEmerald Cruises
18 nights in the Caribbean
Aboard Emerald Azzurra
Bridgetown → Puerto Caldera
AmericasOceania Cruises
10 nights in South America
Aboard Oceania Marina
Panama City → Miami
Panama CanalNorwegian Cruise Line
15 nights: Cabo San Lucas, the Panama Canal
Aboard Norwegian Encore
Los Angeles → Miami
Panama CanalVirgin Voyages
17 nights: Cabo San Lucas, the Panama Canal
Aboard Brilliant Lady
Los Angeles → Miami
Caribbean & Central AmericaExplora Journeys
10 nights: Puerto Vallarta
Aboard EXPLORA III
Miami → Los Angeles
World CruiseSilversea
10 nights: Buenos Aires & Rio de Janeiro
Aboard Silver Shadow
Miami → Nice
AmericasRegent Seven Seas Cruises
11 nights: Cozumel, South America
Aboard Seven Seas Prestige
Panama City → Miami
AmericasRegent Seven Seas Cruises
14 nights in South America
Aboard Seven Seas Grandeur
Panama City → Miami
AmericasRegent Seven Seas Cruises
14 nights: Cozumel, South America
Aboard Seven Seas Splendor
Miami → Panama City
Panama CanalNorwegian Cruise Line
16 nights: Cabo San Lucas, the Panama Canal
Aboard Norwegian Bliss
Los Angeles → New York
Panama CanalNorwegian Cruise Line
16 nights: Cabo San Lucas, the Panama Canal
Aboard Norwegian Joy
Los Angeles → Miami
Panama CanalNorwegian Cruise Line
16 nights: Cabo San Lucas, the Panama Canal
Aboard Norwegian Star
San Diego → Miami
AmericasRegent Seven Seas Cruises
16 nights in South America
Aboard Seven Seas Mariner
Callao → Miami
South AmericaHolland America Line
17 nights: Grand Cayman, South America
Aboard Nieuw Amsterdam
San Antonio → Fort Lauderdale
AmericasSilversea
18 nights: Cozumel, South America
Aboard Silver Nova
Valparaiso → Miami
World JourneyExplora Journeys
128 nights: Singapore & Barcelona
Aboard EXPLORA I
Dubai → Barcelona
AmericasEmerald Cruises
Coastal Adventures: Costa Rica & Panama
Aboard Emerald Azzurra
Puerto Caldera → Panama City
AmericasOceania Cruises
10 nights: Cozumel, South America
Aboard Oceania Marina
Miami → Panama City
Central & North America Pacific CoastExplora Journeys
11 nights: Puerto Vallarta & Vancouver
Aboard EXPLORA III
Panama City → Vancouver
AmericasSilversea
14 nights in South America
Aboard Silver Shadow
Cartagena → Valparaiso
AmericasRegent Seven Seas Cruises
12 nights in South America
Aboard Seven Seas Prestige
Panama City → Miami
AmericasRegent Seven Seas Cruises
14 nights in South America
Aboard Seven Seas Grandeur
Miami → Panama City
PacificRegent Seven Seas Cruises
28 nights: Cabo San Lucas & Honolulu
Aboard Seven Seas Splendor
Panama City → Papeete
Panama CanalNorwegian Cruise Line
17 nights: Cabo San Lucas, the Panama Canal
Aboard Norwegian Bliss
Los Angeles → New York
CaribbeanNorwegian Cruise Line
17 nights: Cabo San Lucas, the Caribbean
Aboard Norwegian Joy
Los Angeles → Miami
South AmericaHolland America Line
32 nights: Buenos Aires & Ushuaia, South America
Aboard Nieuw Amsterdam
Buenos Aires → Fort Lauderdale
AmericasEmerald Cruises
7 nights in South America
Aboard Emerald Azzurra
Panama City → Puerto Caldera
AmericasOceania Cruises
10 nights: Cozumel, South America
Aboard Oceania Marina
Panama City → Miami
Caribbean & Central AmericaExplora Journeys
17 nights: San Juan
Aboard EXPLORA III
San Juan → Panama City
CaribbeanRegent Seven Seas Cruises
12 nights: Cabo San Lucas, the Caribbean
Aboard Seven Seas Prestige
Los Angeles → Panama City
AmericasRegent Seven Seas Cruises
The South America loop
Aboard Seven Seas Grandeur
Round-trip from Panama City
PacificRegent Seven Seas Cruises
42 nights: Cozumel & Honolulu
Aboard Seven Seas Splendor
Miami → Papeete
AmericasEmerald Cruises
11 nights in South America
Aboard Emerald Azzurra
Bridgetown → Panama City
AmericasOceania Cruises
10 nights in South America
Aboard Oceania Marina
Panama City → Miami
AmericasRegent Seven Seas Cruises
12 nights in South America
Aboard Seven Seas Prestige
Miami → Panama City
World CruiseRegent Seven Seas Cruises
127 nights: Honolulu & Singapore
Aboard Seven Seas Splendor
Miami → Civitavecchia
AmericasEmerald Cruises
11 nights in South America
Aboard Emerald Azzurra
Panama City → Bridgetown
AmericasOceania Cruises
10 nights: Cozumel, South America
Aboard Oceania Marina
Miami → Panama City
AmericasRegent Seven Seas Cruises
26 nights in South America
Aboard Seven Seas Prestige
Panama City → Lisbon
World CruiseRegent Seven Seas Cruises
141 nights: Honolulu & Singapore
Aboard Seven Seas Splendor
Miami → New York
AmericasEmerald Cruises
12 nights in South America
Aboard Emerald Azzurra
Puerto Caldera → San José
AmericasOceania Cruises
20 nights: Cozumel
Aboard Oceania Marina
Round-trip from Miami
AmericasEmerald Cruises
12 nights in South America
Aboard Emerald Azzurra
San José → Puerto Caldera
AmericasOceania Cruises
20 nights: Cozumel
Aboard Oceania Marina
Round-trip from Miami
CaribbeanEmerald Cruises
18 nights in the Caribbean
Aboard Emerald Azzurra
Bridgetown → Panama City
CaribbeanOceania Cruises
20 nights: Cozumel, the Caribbean
Aboard Oceania Marina
Round-trip from Miami
Frequently asked
- How many cruises to Panama City does NestCruise have?
- 50 live sailings, 10 to 28 nights. A NestCruise advisor narrows them to the one that fits.
- Which cruise lines visit Panama City?
- Regent Seven Seas Cruises, Emerald Cruises, Oceania Cruises and Norwegian Cruise Line, among others.
- How long are cruises to Panama City?
- Most run 10 to 28 nights.
- How much do cruises to Panama City cost?
- NestCruise doesn't publish fares — it's a quote-only concierge. Share your dates and party size and an advisor prices your exact sailing at no cost.