Cruise itinerary
18-Night Pacific Cruise from Panama City
18 nights · Pacific · 12 ports of call
18-night Pacific cruise aboard EXPLORA III, departing Panama City and calling at At Sea, Acajutla, Puerto Quetzal, Puerto Madero, Huatulco (Santa María Huatulco) and Puerto Vallarta and 5 more.
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- No booking fees
- 10,000+ sailings
At a glance
- Ship
- EXPLORA III
- Cruise line
- Explora Journeys
- Duration
- 18 nights
- Region
- Pacific
- Departs
- Panama City
- Returns
- Vancouver, British Columbia
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact EXPLORA III sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1
Panama City
Depart 20:00
Panama's capital, where a glass-tower skyline meets the Pacific entrance to the famous canal. The colonial Casco Viejo quarter holds plazas and churches, while the Miraflores locks and the rainforest of Soberanía National Park sit close by.
- Panama Canal
- Casco Viejo
- Miraflores Locks
- Day2
At Sea
- Day3
At Sea
- Day4
Acajutla
Arrive 08:00 · Depart 18:00
- Day5
Puerto Quetzal
Arrive 08:00 · Depart 18:00
Guatemala's main Pacific port, a working harbour backed by volcanic highlands. It opens the way to colonial Antigua with its cobbled streets and ruined convents, the coffee farms on the slopes and Lake Atitlán's volcano-ringed shore.
- Antigua Guatemala
- Lake Atitlán
- Coffee plantations
- Day6
Puerto Madero
Arrive 08:00 · Depart 17:00
- Day7
Huatulco (Santa María Huatulco)
Arrive 08:00 · Depart 17:00
- Day8
At Sea
- Day9
Puerto Vallarta
Arrive 09:00 · Depart 17:00
A resort city on Mexico's Pacific coast, set where the Sierra Madre meets Banderas Bay. Its cobbled Zona Romántica and the seaside Malecón promenade anchor an old town of churches and galleries, with whale-watching in the bay through the winter months.
- The Malecón
- Zona Romántica
- Banderas Bay
- Day10
At Sea
- Day11
At Sea
- Day12
Los Angeles, California
Arrive 08:00 · Depart 21:00
The sprawling Pacific gateway of southern California, with most cruises sailing from the neighbouring Port of Los Angeles at San Pedro. The morning leaves time for Hollywood, the beaches at Santa Monica or the galleries downtown before departure.
- Hollywood
- Santa Monica Pier
- Getty Center
- Day13
San Diego, California
Arrive 08:00 · Depart 19:00
A relaxed harbour city in southern California, known for its mild climate and broad natural bay. The waterfront holds the historic Gaslamp Quarter and maritime museums, with the green expanse of Balboa Park and its zoo just inland.
- Balboa Park
- Gaslamp Quarter
- San Diego Zoo
- Day14
At Sea
- Day15
San Francisco, California
Arrive 09:00
A hill-built city on a peninsula between the Pacific and San Francisco Bay, known for the Golden Gate Bridge, cable cars, and Victorian rowhouses. Ships dock near the Embarcadero, within reach of Fisherman's Wharf, Chinatown, and ferries to Alcatraz.
- Golden Gate Bridge
- Cable cars
- Alcatraz Island
- Day16
San Francisco, California
Depart 02:00
A hill-built city on a peninsula between the Pacific and San Francisco Bay, known for the Golden Gate Bridge, cable cars, and Victorian rowhouses. Ships dock near the Embarcadero, within reach of Fisherman's Wharf, Chinatown, and ferries to Alcatraz.
- Golden Gate Bridge
- Cable cars
- Alcatraz Island
- Day17
At Sea
- Day18
Victoria, British Columbia
Arrive 07:00 · Depart 14:00
The capital of British Columbia, set on the southern tip of Vancouver Island in Canada. The Inner Harbour is framed by the ivy-clad Empress Hotel and the domed Parliament Buildings, with whale-watching boats and Butchart Gardens close at hand.
- Inner Harbour
- Butchart Gardens
- Empress Hotel
- Day19
Vancouver, British Columbia
Arrive 07:00
A Pacific coast city in British Columbia and the main homeport for Alaska cruises. Ships sail from beneath the sails of Canada Place, with Stanley Park's seawall, the totem poles and the cobbled Gastown district close to the terminal.
- Stanley Park
- Gastown
- Gateway to Alaska
Upcoming departures
- 22 Apr 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
18-Night Pacific Cruise from Panama City FAQ
Which ports does this cruise visit?
This 18-night Pacific cruise calls at Panama City, At Sea, Acajutla, Puerto Quetzal, Puerto Madero, Huatulco (Santa María Huatulco), Puerto Vallarta, Los Angeles, California, San Diego, California, San Francisco, California, Victoria, British Columbia and Vancouver, British Columbia.
How many days are spent at sea?
7 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Panama City and ends in Vancouver, British Columbia.
How long is this cruise?
18 nights aboard EXPLORA III.
When does this itinerary sail?
Upcoming departures include 22 Apr 2027. A NestCruise advisor can confirm current availability.