

Cruise itinerary
16-Night Americas Cruise from Callao
16 nights · Americas · 15 ports of call
16-night Americas cruise aboard Seven Seas Mariner, departing Callao and calling at Salaverry, Cruising the Pacific Ocean, Guayaquil, Manta, Golfito and Panama City and 8 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Cruise line
- Regent Seven Seas Cruises
- Duration
- 16 nights
- Region
- Americas · South America
- Departs
- Callao
- Returns
- Miami, Florida
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Seven Seas Mariner sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Callao
Peru's chief seaport, on the Pacific beside Lima. Ships dock here for the colonial centre and museums of the capital, the cliff-top Miraflores district above the ocean, and onward journeys toward Machu Picchu and the Andean highlands.
- Gateway to Lima
- Miraflores
- Historic centre
- Day2

Callao
Depart 17:00
Peru's chief seaport, on the Pacific beside Lima. Ships dock here for the colonial centre and museums of the capital, the cliff-top Miraflores district above the ocean, and onward journeys toward Machu Picchu and the Andean highlands.
- Gateway to Lima
- Miraflores
- Historic centre
- Day3

Salaverry
Arrive 10:00 · Depart 18:00
- Day4
Cruising the Pacific Ocean
- Day5

Guayaquil
Arrive 07:00 · Depart 17:00
- Day6

Manta
Arrive 08:00 · Depart 18:00
- Day7
Cruising the Pacific Ocean
- Day8

Golfito
Arrive 07:00 · Depart 14:00
- Day9

Panama City
Arrive 13:00 · Depart 22:00
Panama's capital, where a glass-tower skyline meets the Pacific entrance to the famous canal. The colonial Casco Viejo quarter holds plazas and churches, while the Miraflores locks and the rainforest of Soberanía National Park sit close by.
- Panama Canal
- Casco Viejo
- Miraflores Locks
- Day10
Panama Canal Transit
Arrive 07:00 · Depart 18:00
- Day11

Puerto Limón
Arrive 08:00 · Depart 18:00
A Caribbean port on Costa Rica's humid eastern coast, the country's main Atlantic harbour. It opens onto rainforest, banana plantations and the canals of Tortuguero, with white-faced monkeys and sloths a frequent sight on excursions inland.
- Tortuguero canals
- Rainforest wildlife
- Banana country
- Day12
Cruising the Caribbean Sea
- Day13

Roatán Island
Arrive 11:00 · Depart 18:00
An island off the northern coast of Honduras in the western Caribbean, part of the Bay Islands. Roatán is known for the Mesoamerican Barrier Reef just offshore, the dive sites and beaches around West End and West Bay, and forested inland hills.
- West Bay Beach
- Barrier reef diving
- West End
- Day14

Harvest Caye
Arrive 08:00 · Depart 17:00
- Day15

Costa Maya
Arrive 09:00 · Depart 17:00
A purpose-built cruise port on Mexico's Caribbean coast in Quintana Roo, on the southern Costa Maya. It serves as a gateway to Mayan ruins at Chacchoben and Kohunlich, plus nearby reef snorkelling and the laid-back fishing village of Mahahual.
- Chacchoben ruins
- Mahahual village
- Reef snorkelling
- Day16
Cruising the Florida Straits
- Day17

Miami, Florida
Arrive 07:00 · Depart 17:00
The cruise capital of the world — Miami sends more ships to sea than any port on earth. Most sailings board mid-afternoon, leaving the morning for South Beach, Little Havana or the Wynwood murals before you cast off.
- South Beach
- Little Havana
- Wynwood murals
Upcoming departures
- 10 Mar 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
16-Night Americas Cruise from Callao FAQ
Which ports does this cruise visit?
This 16-night Americas cruise calls at Callao, Salaverry, Cruising the Pacific Ocean, Guayaquil, Manta, Golfito, Panama City, Panama Canal Transit, Puerto Limón, Cruising the Caribbean Sea, Roatán Island, Harvest Caye, Costa Maya, Cruising the Florida Straits and Miami, Florida.
How many days are spent at sea?
4 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Callao and ends in Miami, Florida.
How long is this cruise?
16 nights aboard Seven Seas Mariner.
When does this itinerary sail?
Upcoming departures include 10 Mar 2027. A NestCruise advisor can confirm current availability.