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Southern Europe cruises

952 live sailings explore Southern Europe — 7 to 19 nights, departing 63 ports, across 16 lines. A NestCruise advisor narrows them to the one that fits.

952 sailings
Italy, Greece, TurkeyEurope

MSC Cruises

7 nights: Piraeus & Istanbul, the Mediterranean

Aboard MSC Orchestra

Round-trip from Bari

Sails weekly, Nov 2026 – Jan 2028
Barcelona, Marseille, Genoa, Civitavecchia, Messina, Valletta, BarcelonaEurope

MSC Cruises

7 nights: Barcelona & Civitavecchia, the Mediterranean

Aboard MSC World Asia

Round-trip from Barcelona

Sails weekly, Dec 2026 – Dec 2027
Italy, Greece, TurkeyEurope

MSC Cruises

7 nights: Naples & Mykonos, the Mediterranean

Aboard MSC Divina

Round-trip from Naples

Sails weekly, Apr 2027 – Oct 2027
Italy, GreeceEurope

MSC Cruises

7 nights: Venice & Mykonos, the Mediterranean

Aboard MSC Lirica

Round-trip from Ancona

Overnight in Mykonos
Sails weekly, Apr 2027 – Oct 2027
Italy, Croatia, GreeceEurope

MSC Cruises

7 nights: Venice & Dubrovnik, the Mediterranean

Aboard MSC Armonia

Round-trip from Brindisi

Sails weekly, Apr 2027 – Oct 2027
Greek Isles CruiseEurope

Royal Caribbean International

7 nights: Santorini & Mykonos, the Mediterranean

Aboard Odyssey of the Seas

Round-trip from Civitavecchia

from$903pp · cruise fare≈ $129/night pp

Fares checked nightly

Sails weekly, May 2027 – Oct 2027
Genoa, Marseille, Valencia, Ibiza, Cagliari, CivitavecchiaEurope

MSC Cruises

6 nights: Ibiza & Civitavecchia, the Mediterranean

Aboard MSC Musica

Genoa → Civitavecchia

Sails weekly, Apr 2027 – Oct 2027
Spain, France, ItalyEurope

MSC Cruises

7 nights: Barcelona & Civitavecchia, the Mediterranean

Aboard MSC Seaview

Round-trip from Barcelona

Nov 2026 – Aug 2027Next 5 Nov 2026 · 15 more
Western Mediterranean CruiseEurope

Royal Caribbean International

7 nights: Civitavecchia & Barcelona, the Mediterranean

Aboard Legend of the Seas

Round-trip from Civitavecchia

from$1,576pp · cruise fare≈ $225/night pp

Fares checked nightly

Sails weekly, May 2027 – Oct 2027
Barcelona, Marseille, Genoa, Naples, Palermo, La Goulette, BarcelonaEurope

MSC Cruises

7 nights: Barcelona & Naples, the Mediterranean

Aboard MSC Euribia

Round-trip from Barcelona

Sails every two weeks, Nov 2026 – Jan 2028
Marseille, Genoa, Naples, Messina, Valletta, BarcelonaEurope

MSC Cruises

6 nights: Naples & Barcelona, the Mediterranean

Aboard MSC World Europa

Marseille → Barcelona

Sails weekly, Apr 2027 – Jun 2027
Barcelona, La Goulette, Palermo, Naples, Livorno, Marseille, BarcelonaEurope

MSC Cruises

7 nights: Barcelona & Naples, the Mediterranean

Aboard MSC Virtuosa

Round-trip from Barcelona

Sails weekly, Apr 2027 – Nov 2027
Italy, France, SpainEurope

MSC Cruises

7 nights: Civitavecchia & Barcelona, the Mediterranean

Aboard MSC Fantasia

Round-trip from Civitavecchia

Sails weekly, Apr 2027 – Sep 2027
France, Italy, SpainEurope

MSC Cruises

7 nights: Marseille & Barcelona, the Mediterranean

Aboard MSC Sinfonia

Round-trip from Marseille

Sails weekly, Nov 2026 – Apr 2027
Greek Isles CruiseEurope

Royal Caribbean International

7 nights: Santorini & Mykonos, the Mediterranean

Aboard Brilliance of the Seas

Round-trip from Ravenna

from$714pp · cruise fare≈ $102/night pp

Fares checked nightly

May 2027 – Oct 2027Next 15 May 2027 · 15 more
Italy, Greece & CroatiaEurope

Celebrity Cruises

10 nights: Civitavecchia & Dubrovnik, the Mediterranean

Aboard Celebrity Ascent

Round-trip from Civitavecchia

from$1,849pp · cruise fare≈ $185/night pp

Fares checked nightly

May 2027 – Oct 2027Next 14 May 2027 · 7 more
Italian Riviera, France & SpainEurope

Celebrity Cruises

9 nights: Civitavecchia & Barcelona, the Mediterranean

Aboard Celebrity Equinox

Civitavecchia → Barcelona

Overnight in La Spezia

from$1,063pp · cruise fare≈ $118/night pp

Fares checked nightly

Sails monthly, May 2027 – Oct 2027
Best of GreeceEurope

Celebrity Cruises

9 nights: Mykonos & Santorini, the Mediterranean

Aboard Celebrity Infinity

Round-trip from Piraeus

from$900pp · cruise fare≈ $100/night pp

Fares checked nightly

Apr 2027 – Apr 2028Next 2 Apr 2027 · 8 more
Greek Isles & MaltaEurope

Celebrity Cruises

7 nights: Barcelona & Mykonos, the Mediterranean

Aboard Celebrity Xcel

Barcelona → Piraeus

from$1,149pp · cruise fare≈ $164/night pp

Fares checked nightly

Sails every two weeks, Jun 2027 – Sep 2027
Greek Islands & Turkish CoastlinesEurope

Emerald Cruises

7 nights: Mykonos & Santorini, the Mediterranean

Aboard Emerald Azzurra

Round-trip from Piraeus

↓ $1,101 this monthIncludes Preferred Savings

from$7,194pp · cruise fare≈ $1,028/night pp

Fares checked nightly

May 2027 – Aug 2027Next 29 May 2027 · 2 more
Greece, Egypt & Cyprus CruiseEurope

Royal Caribbean International

7 nights: Piraeus & Santorini, the Mediterranean

Aboard Rhapsody of the Seas

Round-trip from Piraeus

Overnight in Alexandria

from$672pp · cruise fare≈ $96/night pp

Fares checked nightly

May 2027 – Oct 2027Next 21 May 2027 · 7 more
Marseille, Tarragona, Civitavecchia, Genoa, Naples, Messina, Valletta, Barcelona, MarseilleEurope

MSC Cruises

10 nights: Civitavecchia & Barcelona, the Mediterranean

Aboard MSC Magnifica

Round-trip from Marseille

Nov 2026 – Dec 2027Next 4 Nov 2026 · 7 more
Iconic Greek Islands - 3Nights (Mar & Nov)Europe

Celestyal Cruises

3 nights: Mykonos & Santorini, the Mediterranean

Aboard Celestyal Discovery

Mykonos → Athens

Rare itinerary
Nov 2026Next 6 Nov 2026 · 1 more
Flavors of Portugal & Spain (Taste of Christmas)Europe

AmaWaterways

Flavors of Portugal & Spain (Taste of Christmas)

Aboard AmaVida

Vega de Terron → Porto

↓ $1,250 this monthOvernight in Régua

from$2,829pp · cruise fare≈ $404/night pp

Fares checked nightly

Nov 2026 – Nov 2027Next 21 Nov 2026 · 5 more
Idyllic Greece -7NightsEurope

Celestyal Cruises

7 nights: Santorini & Mykonos, the Mediterranean

Aboard Celestyal Journey

Round-trip from Piraeus

↓ $541 this monthRare itinerary

from$979pp · cruise fare≈ $140/night pp

Fares checked nightly

Mar 2027Next 13 Mar 2027
Hidden Gems of the Croatian RivieraEurope

Emerald Cruises

7 nights: Dubrovnik & Venice, the Mediterranean

Aboard Emerald Kaia

Dubrovnik → Venice

Overnight in DubrovnikRare itinerary
May 2027Next 29 May 2027
Classical GreeceEurope

Emerald Cruises

7 nights: Mykonos & Santorini, the Mediterranean

Aboard Emerald Raiya

Round-trip from Piraeus

↓ $683 this monthIncludes Preferred Savings

from$6,762pp · cruise fare≈ $966/night pp

Fares checked nightly

Jun 2027 – Jul 2028Next 26 Jun 2027 · 5 more
French & Italian Rivieras with CorsicaEurope

Emerald Cruises

7 nights: Nice & Civitavecchia, the Mediterranean

Aboard Emerald Sakara

Nice → Civitavecchia

↓ $581 this monthIncludes Preferred Savings

from$5,714pp · cruise fare≈ $816/night pp

Fares checked nightly

May 2027 – May 2028Next 20 May 2027 · 3 more
Greece & Croatia CruiseEurope

Royal Caribbean International

7 nights: Dubrovnik & Santorini, the Mediterranean

Aboard Explorer of the Seas

Round-trip from Ravenna

Rare itinerary

from$898pp · cruise fare≈ $128/night pp

Fares checked nightly

Jul 2027Next 12 Jul 2027
Greece, Turkey, Italy, CroatiaEurope

MSC Cruises

9 nights: Istanbul & Split, the Mediterranean

Aboard MSC Splendida

Round-trip from Piraeus

Sails every two weeks, Apr 2027 – Jul 2027
Secrets of the Douro & LisbonEurope

Emerald Cruises

Secrets of the Douro & Lisbon

Aboard Emerald Radiance

Porto → Lisbon

Overnight in PortoRare itinerary

from$7,175pp · cruise fare≈ $718/night pp

Fares checked nightly

Nov 2026Next 7 Nov 2026
Barcelona to BarcelonaEurope

Silversea

10 nights: Barcelona & Cannes, the Mediterranean

Aboard Silver Ray

Round-trip from Barcelona

↓ $3,000 this monthOvernight in Málaga

from$4,750pp · cruise fare≈ $475/night pp

Fares checked nightly

Nov 2026 – Oct 2027Next 8 Nov 2026 · 4 more
Vida Portugal: Vineyards & Villages Along the Douro with a Taste of MadeiraEurope

Avalon Waterways

Vida Portugal: Vineyards & Villages Along the Douro with a Taste of Madeira

Aboard Avalon Alegria

Porto → Lisbon

Overnight in Porto
Sails weekly, Mar 2027 – Apr 2027
Athens to AthensEurope

Silversea

11 nights: Istanbul & Mykonos, the Mediterranean

Aboard Silver Nova

Round-trip from Piraeus

↓ $3,000 this monthOvernight in Istanbul

from$6,400pp · cruise fare≈ $582/night pp

Fares checked nightly

Jun 2027 – Oct 2027Next 16 Jun 2027 · 3 more
7-Day Western Mediterranean: Italy, France & GibraltarEurope

Holland America Line

7 nights: Civitavecchia & Barcelona, the Mediterranean

Aboard Oosterdam

Civitavecchia → Barcelona

Rare itinerary
Jun 2027 – Jul 2027Next 19 Jun 2027 · 1 more
Fusina to FusinaEurope

Silversea

9 nights: Dubrovnik & Kotor, the Mediterranean

Aboard Silver Spirit

Round-trip from Fusina

↓ $3,000 this month

from$3,550pp · cruise fare≈ $394/night pp

Fares checked nightly

Sep 2027 – Nov 2027Next 27 Sep 2027 · 4 more
Greco-Roman WorldEurope

Oceania Cruises

7 nights: Valletta & Civitavecchia, the Mediterranean

Aboard Oceania Allura

Piraeus → Civitavecchia

May 2027 – Oct 2027Next 7 May 2027 · 3 more
Spain & Morocco CruiseEurope

Royal Caribbean International

7 nights: Barcelona, the Mediterranean

Aboard Mariner of the Seas

Round-trip from Barcelona

from$726pp · cruise fare≈ $104/night pp

Fares checked nightly

May 2027 – Oct 2027Next 11 May 2027 · 3 more
10-Day Greek Isles  Turkey & ItalyEurope

Carnival Cruise Line

10 nights: Mykonos & Barcelona, the Mediterranean

Aboard Carnival Sunshine

Civitavecchia → Barcelona

from$733pp · cruise fare≈ $73/night pp

Fares checked nightly

Sails monthly, Jul 2027 – Sep 2027
Italy, France & Spain Cruise: Rome, Florence & BarcelonaEurope

Azamara

7 nights: Civitavecchia & Barcelona, the Mediterranean

Aboard Azamara Journey

Civitavecchia → Barcelona

Overnight in LivornoRare itinerary

from$1,719pp · cruise fare≈ $246/night pp

Fares checked nightly

May 2027 – Mar 2028Next 15 May 2027 · 2 more
Cities and splendours of the AdriaticEurope

PONANT EXPLORATIONS

7 nights: Dubrovnik & Venice, the Mediterranean

Aboard Le Dumont-d'Urville

Dubrovnik → Venice

Overnight in DubrovnikRare itinerary
Sails every two weeks, Aug 2027 – Sep 2027
Greek Isles & Mykonos OvernightEurope

Virgin Voyages

7 nights: Mykonos & Santorini, the Mediterranean

Aboard Scarlet Lady

Round-trip from Piraeus

↓ $1,116 this monthOvernight in Mykonos

from$2,786pp · cruise fare≈ $398/night pp

Fares checked nightly

May 2027 – Aug 2027Next 23 May 2027 · 1 more
Croatia Intensive Cruise: Zadar, Split & DubrovnikEurope

Azamara

9 nights: Dubrovnik & Kotor, the Mediterranean

Aboard Azamara Onward

Fusina → Piraeus

Rare itinerary

from$3,189pp · cruise fare≈ $354/night pp

Fares checked nightly

Jun 2027 – Jul 2028Next 20 Jun 2027 · 2 more
Venetian & Roman RevelryEurope

Oceania Cruises

9 nights: Venice & Barcelona, the Mediterranean

Aboard Oceania Sirena

Venice → Barcelona

Rare itinerary
Apr 2027 – Aug 2027Next 17 Apr 2027 · 2 more
10-Day Greek Isles  Turkey & ItalyEurope

Carnival Cruise Line

10 nights: Santorini & Mykonos, the Mediterranean

Aboard Carnival Miracle

Round-trip from Civitavecchia

Rare itinerary

from$958pp · cruise fare≈ $96/night pp

Fares checked nightly

Sails every two weeks, Sep 2027 – Oct 2027
Andalusia and Moroccan shoresEurope

PONANT EXPLORATIONS

The Mediterranean loop

Aboard Le Bougainville

Round-trip from Málaga

Rare itinerary
Nov 2026Next 10 Nov 2026 · 1 more
The French Riviera Under Le Ponant’s SailsEurope

PONANT EXPLORATIONS

7 nights: Nice & Cannes, the Mediterranean

Aboard Le Ponant

Round-trip from Nice

Rare itinerary
Sails every two weeks, May 2027
Legendary shores of Italy and CroatiaEurope

PONANT EXPLORATIONS

8 nights: Civitavecchia & Venice, the Mediterranean

Aboard Le Boréal

Civitavecchia → Venice

Rare itinerary
Sails weekly, May 2027

Frequently asked

How many Southern Europe cruises does NestCruise have?
952 live sailings, 7 to 19 nights. A NestCruise advisor narrows them to the one that fits.
Which cruise lines run Southern Europe cruises?
MSC Cruises, Regent Seven Seas Cruises, Azamara and Oceania Cruises, among others.
How long are Southern Europe cruises?
Most run 7 to 19 nights.
How much do Southern Europe cruises cost?
NestCruise doesn't publish fares — it's a quote-only concierge. Share your dates and party size and an advisor prices your exact sailing at no cost.