Cruise itinerary
21-Night Caribbean Cruise from Miami, Florida
21 nights · Caribbean · 15 ports of call
21-night Caribbean cruise aboard EXPLORA III, departing Miami, Florida and calling at At Sea, Ocho Rios, Willemstad, Oranjestad, Santa Marta and Cartagena and 8 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Ship
- EXPLORA III
- Cruise line
- Explora Journeys
- Duration
- 21 nights
- Region
- Caribbean · Americas · South America
- Departs
- Miami, Florida
- Returns
- Los Angeles, California
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact EXPLORA III sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1
Miami, Florida
Depart 17:00
The cruise capital of the world — Miami sends more ships to sea than any port on earth. Most sailings board mid-afternoon, leaving the morning for South Beach, Little Havana or the Wynwood murals before you cast off.
- South Beach
- Little Havana
- Wynwood murals
- Day2
At Sea
- Day3
Ocho Rios
Arrive 09:00 · Depart 18:00
A resort town on Jamaica's north coast, set among green hills and a string of beaches. The terraced cascades of Dunn's River Falls are the headline attraction, with botanical gardens, river tubing and reggae-filled markets close to the cruise pier.
- Dunn's River Falls
- Resort beaches
- Botanical gardens
- Day4
At Sea
- Day5
Willemstad
Arrive 09:00 · Depart 23:00
The capital of Curaçao in the southern Caribbean, with a UNESCO-listed centre of Dutch colonial architecture. Willemstad is known for the candy-coloured waterfront of Handelskade, the swinging Queen Emma pontoon bridge, and its floating market.
- Handelskade façades
- Queen Emma Bridge
- Floating Market
- Day6
Oranjestad
Arrive 08:00 · Depart 16:00
The capital of Aruba, set on the island's leeward south coast in the southern Caribbean. Oranjestad is known for its Dutch colonial façades along Wilhelminastraat, a free streetcar through downtown, and white-sand beaches like Eagle and Palm just north.
- Eagle Beach
- Palm Beach
- Dutch colonial centre
- Day7
Santa Marta
Arrive 09:00 · Depart 20:00
- Day8
Cartagena
Arrive 08:00
A walled colonial city on Colombia's Caribbean coast, its old town a maze of pastel houses, balconies and shaded plazas. Massive stone ramparts ring the centre, with the San Felipe fortress guarding the harbour above.
- Walled old town
- San Felipe fortress
- Plaza Santo Domingo
- Day9
Cartagena
Depart 12:00
A walled colonial city on Colombia's Caribbean coast, its old town a maze of pastel houses, balconies and shaded plazas. Massive stone ramparts ring the centre, with the San Felipe fortress guarding the harbour above.
- Walled old town
- San Felipe fortress
- Plaza Santo Domingo
- Day10
Panama Canal Transit
Arrive 06:00 · Depart 06:30
Panama City
Arrive 20:00
Panama's capital, where a glass-tower skyline meets the Pacific entrance to the famous canal. The colonial Casco Viejo quarter holds plazas and churches, while the Miraflores locks and the rainforest of Soberanía National Park sit close by.
- Panama Canal
- Casco Viejo
- Miraflores Locks
- Day11
Panama City
Arrive 08:00 · Depart 20:00
Panama's capital, where a glass-tower skyline meets the Pacific entrance to the famous canal. The colonial Casco Viejo quarter holds plazas and churches, while the Miraflores locks and the rainforest of Soberanía National Park sit close by.
- Panama Canal
- Casco Viejo
- Miraflores Locks
- Day12
At Sea
- Day13
At Sea
- Day14
Acajutla
Arrive 08:00 · Depart 18:00
- Day15
Puerto Quetzal
Arrive 08:00 · Depart 18:00
Guatemala's main Pacific port, a working harbour backed by volcanic highlands. It opens the way to colonial Antigua with its cobbled streets and ruined convents, the coffee farms on the slopes and Lake Atitlán's volcano-ringed shore.
- Antigua Guatemala
- Lake Atitlán
- Coffee plantations
- Day16
Puerto Madero
Arrive 08:00 · Depart 17:00
- Day17
Huatulco (Santa María Huatulco)
Arrive 08:00 · Depart 17:00
- Day18
At Sea
- Day19
Puerto Vallarta
Arrive 09:00 · Depart 17:00
A resort city on Mexico's Pacific coast, set where the Sierra Madre meets Banderas Bay. Its cobbled Zona Romántica and the seaside Malecón promenade anchor an old town of churches and galleries, with whale-watching in the bay through the winter months.
- The Malecón
- Zona Romántica
- Banderas Bay
- Day20
At Sea
- Day21
At Sea
- Day22
Los Angeles, California
Arrive 08:00
The sprawling Pacific gateway of southern California, with most cruises sailing from the neighbouring Port of Los Angeles at San Pedro. The morning leaves time for Hollywood, the beaches at Santa Monica or the galleries downtown before departure.
- Hollywood
- Santa Monica Pier
- Getty Center
Upcoming departures
- 12 Apr 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
21-Night Caribbean Cruise from Miami, Florida FAQ
Which ports does this cruise visit?
This 21-night Caribbean cruise calls at Miami, Florida, At Sea, Ocho Rios, Willemstad, Oranjestad, Santa Marta, Cartagena, Panama Canal Transit, Panama City, Acajutla, Puerto Quetzal, Puerto Madero, Huatulco (Santa María Huatulco), Puerto Vallarta and Los Angeles, California.
How many days are spent at sea?
7 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Miami, Florida and ends in Los Angeles, California.
How long is this cruise?
21 nights aboard EXPLORA III.
When does this itinerary sail?
Upcoming departures include 12 Apr 2027. A NestCruise advisor can confirm current availability.