

Cruise itinerary
7-Night Americas Cruise from Panama City
7 nights · Americas · 9 ports of call
7-night Americas cruise aboard Emerald Azzurra, departing Panama City and calling at Pearl Islands, Playa Muerto, Darién National Park, Darién National Park, Cébaco Island, Golfito and Quepos (Puerto Quepos) and 2 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Emerald Azzurra
- Cruise line
- Emerald Cruises
- Duration
- 7 nights
- Region
- Americas · South America
- Departs
- Panama City
- Returns
- Puerto Caldera
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Emerald Azzurra sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Panama City
Panama's capital, where a glass-tower skyline meets the Pacific entrance to the famous canal. The colonial Casco Viejo quarter holds plazas and churches, while the Miraflores locks and the rainforest of Soberanía National Park sit close by.
- Panama Canal
- Casco Viejo
- Miraflores Locks
- Day2

Pearl Islands
- Day3
Playa Muerto, Darién National Park
Darién National Park
- Day4
Cébaco Island
- Day5

Golfito
- Day6

Quepos (Puerto Quepos)
- Day7

Curú Wildlife Refuge
- Day8

Puerto Caldera
Upcoming departures
- 24 Jan 2028
- 24 Jan 2029
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
7-Night Americas Cruise from Panama City FAQ
Which ports does this cruise visit?
This 7-night Americas cruise calls at Panama City, Pearl Islands, Playa Muerto, Darién National Park, Darién National Park, Cébaco Island, Golfito, Quepos (Puerto Quepos), Curú Wildlife Refuge and Puerto Caldera.
How many days are spent at sea?
This is a port-intensive itinerary with no full days at sea.
Where does this cruise depart from?
It departs from Panama City and ends in Puerto Caldera.
How long is this cruise?
7 nights aboard Emerald Azzurra.
When does this itinerary sail?
Upcoming departures include 24 Jan 2028 and 24 Jan 2029. A NestCruise advisor can confirm current availability.