

Cruise itinerary
28-Night Pacific Cruise from Panama City
28 nights · Pacific · 14 ports of call
28-night Pacific cruise aboard Seven Seas Splendor, departing Panama City and calling at Cruising the Pacific Ocean, Puntarenas, Acajutla, Puerto Quetzal, Puerto Vallarta and Cabo San Lucas and 7 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Cruise line
- Regent Seven Seas Cruises
- Duration
- 28 nights
- Region
- Pacific
- Departs
- Panama City
- Returns
- Papeete, Tahiti
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Seven Seas Splendor sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Panama City
Depart 19:00
Panama's capital, where a glass-tower skyline meets the Pacific entrance to the famous canal. The colonial Casco Viejo quarter holds plazas and churches, while the Miraflores locks and the rainforest of Soberanía National Park sit close by.
- Panama Canal
- Casco Viejo
- Miraflores Locks
- Day2
Cruising the Pacific Ocean
- Day3

Puntarenas
Arrive 07:00 · Depart 17:00
A Pacific port city on a narrow sandy spit on Costa Rica's central coast. It serves chiefly as a gateway inland to rainforests and volcanoes, with a long beachfront promenade and boats out to the Gulf of Nicoya's islands.
- Gulf of Nicoya
- Beachfront paseo
- Rainforest gateway
- Day4
Cruising the Pacific Ocean
- Day5

Acajutla
Arrive 07:00 · Depart 17:00
- Day6

Puerto Quetzal
Arrive 07:00 · Depart 17:00
Guatemala's main Pacific port, a working harbour backed by volcanic highlands. It opens the way to colonial Antigua with its cobbled streets and ruined convents, the coffee farms on the slopes and Lake Atitlán's volcano-ringed shore.
- Antigua Guatemala
- Lake Atitlán
- Coffee plantations
- Day7
Cruising the Pacific Ocean
- Day8
Cruising the Pacific Ocean
- Day9

Puerto Vallarta
Arrive 07:00 · Depart 16:00
A resort city on Mexico's Pacific coast, set where the Sierra Madre meets Banderas Bay. Its cobbled Zona Romántica and the seaside Malecón promenade anchor an old town of churches and galleries, with whale-watching in the bay through the winter months.
- The Malecón
- Zona Romántica
- Banderas Bay
- Day10

Cabo San Lucas
Arrive 10:00 · Depart 15:30
A resort town at the southern tip of Mexico's Baja California peninsula, where the desert meets the Pacific and Sea of Cortez. Cabo San Lucas is known for its rock arch at Land's End, sport fishing, and the marina lined with restaurants and boats.
- El Arco
- Lover's Beach
- Cabo marina
- Day11
Cruising the Pacific Ocean
- Day12

Los Angeles, California
Arrive 16:00
The sprawling Pacific gateway of southern California, with most cruises sailing from the neighbouring Port of Los Angeles at San Pedro. The morning leaves time for Hollywood, the beaches at Santa Monica or the galleries downtown before departure.
- Hollywood
- Santa Monica Pier
- Getty Center
- Day13

Los Angeles, California
Depart 17:00
The sprawling Pacific gateway of southern California, with most cruises sailing from the neighbouring Port of Los Angeles at San Pedro. The morning leaves time for Hollywood, the beaches at Santa Monica or the galleries downtown before departure.
- Hollywood
- Santa Monica Pier
- Getty Center
- Day14
Cruising the Pacific Ocean
- Day15
Cruising the Pacific Ocean
- Day16
Cruising the Pacific Ocean
- Day17
Cruising the Pacific Ocean
- Day18
Cruising the Pacific Ocean
- Day19

Honolulu, Hawaii
Arrive 07:00 · Depart 19:00
Hawaii's capital on the island of Oahu, where Waikiki's beach and high-rises meet the volcanic ridge of Diamond Head. The harbour holds the Pearl Harbor memorials, and surf and rainforest valleys lie a short drive away.
- Waikiki Beach
- Diamond Head
- Pearl Harbor
- Day20

Kahului-Maui, Hawaii
Arrive 07:00 · Depart 17:00
The deep-water gateway to Maui, on the island's central isthmus in the Hawaiian chain. Most calls fan out from here to the cliffs and waterfalls of the Road to Hana, the dormant summit of Haleakalā, or the old whaling town of Lahaina.
- Haleakalā summit
- Road to Hana
- Iao Valley
- Day21

Hilo, Hawaii
Arrive 07:00 · Depart 17:00
The largest town on the Big Island of Hawaii, set on a rainy, green bay on the windward coast. It serves as the gateway to Hawaii Volcanoes National Park and is fringed by waterfalls, botanical gardens, and black-sand shorelines.
- Rainbow Falls
- Volcanoes National Park
- Liliʻuokalani Gardens
- Day22
Cruising the Pacific Ocean
- Day23
Cruising the Pacific Ocean
- Day24
Cruising the Pacific Ocean
- Day25
Cruising the Pacific Ocean
- Day26
Cruising the Pacific Ocean
- Day27

Bora-Bora
Arrive 07:00 · Depart 21:00
A volcanic island in French Polynesia, ringed by a turquoise lagoon and a barrier reef. The jagged peak of Mount Otemanu rises at its centre, while overwater bungalows, coral gardens and lagoon excursions draw visitors across the South Pacific.
- Mount Otemanu
- Turquoise lagoon
- Coral gardens
- Day28

Moorea
Arrive 08:00 · Depart 17:00
A volcanic island in French Polynesia in the South Pacific, just northwest of Tahiti. Jagged green peaks rise above two deep bays, Cook's and Opunohu, with a turquoise lagoon, coral reefs and pineapple plantations on the slopes.
- Cook's Bay
- Mount Rotui
- Lagoon snorkelling

Papeete, Tahiti
Arrive 20:00
The capital of French Polynesia, on the island of Tahiti in the South Pacific. Its waterfront market sells black pearls and tropical fruit, food-truck roulottes gather by the harbour at night, and it serves as the gateway to nearby Moorea and Bora Bora.
- Papeete Market
- Black pearls
- Moorea ferry
- Day29

Papeete, Tahiti
The capital of French Polynesia, on the island of Tahiti in the South Pacific. Its waterfront market sells black pearls and tropical fruit, food-truck roulottes gather by the harbour at night, and it serves as the gateway to nearby Moorea and Bora Bora.
- Papeete Market
- Black pearls
- Moorea ferry
Upcoming departures
- 26 Jan 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
28-Night Pacific Cruise from Panama City FAQ
Which ports does this cruise visit?
This 28-night Pacific cruise calls at Panama City, Cruising the Pacific Ocean, Puntarenas, Acajutla, Puerto Quetzal, Puerto Vallarta, Cabo San Lucas, Los Angeles, California, Honolulu, Hawaii, Kahului-Maui, Hawaii, Hilo, Hawaii, Bora-Bora, Moorea and Papeete, Tahiti.
How many days are spent at sea?
15 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Panama City and ends in Papeete, Tahiti.
How long is this cruise?
28 nights aboard Seven Seas Splendor.
When does this itinerary sail?
Upcoming departures include 26 Jan 2027. A NestCruise advisor can confirm current availability.