

Cruise itinerary
10-Night Americas Cruise from Panama City
10 nights · Americas · 9 ports of call
10-night Americas cruise aboard Oceania Marina, departing Panama City and calling at Panama Canal Transit, At Sea, Puerto Limón, Roatán Island, Santo Tomás de Castilla and Costa Maya and 2 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Oceania Marina
- Cruise line
- Oceania Cruises
- Duration
- 10 nights
- Region
- Americas · South America · Panama Canal
- Departs
- Panama City
- Returns
- Miami, Florida
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Oceania Marina sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Panama City
Arrive 07:00 · Depart 17:00
Panama's capital, where a glass-tower skyline meets the Pacific entrance to the famous canal. The colonial Casco Viejo quarter holds plazas and churches, while the Miraflores locks and the rainforest of Soberanía National Park sit close by.
- Panama Canal
- Casco Viejo
- Miraflores Locks
- Day2
Panama Canal Transit
Arrive 06:00 · Depart 18:00
- Day3
At Sea
- Day4

Puerto Limón
Arrive 07:00 · Depart 17:00
A Caribbean port on Costa Rica's humid eastern coast, the country's main Atlantic harbour. It opens onto rainforest, banana plantations and the canals of Tortuguero, with white-faced monkeys and sloths a frequent sight on excursions inland.
- Tortuguero canals
- Rainforest wildlife
- Banana country
- Day5
At Sea
- Day6

Roatán Island
Arrive 08:00 · Depart 18:00
An island off the northern coast of Honduras in the western Caribbean, part of the Bay Islands. Roatán is known for the Mesoamerican Barrier Reef just offshore, the dive sites and beaches around West End and West Bay, and forested inland hills.
- West Bay Beach
- Barrier reef diving
- West End
- Day7

Santo Tomás de Castilla
Arrive 08:00 · Depart 17:00
- Day8

Costa Maya
Arrive 08:00 · Depart 18:00
A purpose-built cruise port on Mexico's Caribbean coast in Quintana Roo, on the southern Costa Maya. It serves as a gateway to Mayan ruins at Chacchoben and Kohunlich, plus nearby reef snorkelling and the laid-back fishing village of Mahahual.
- Chacchoben ruins
- Mahahual village
- Reef snorkelling
- Day9

Cozumel
Arrive 07:00 · Depart 17:00
An island off Mexico's Yucatán coast in the Caribbean, a leading port for snorkelling and diving. Ships dock beside its reefs, part of the Mesoamerican system, with beach clubs, Mayan ruins and the resort strip of the Riviera Maya within reach.
- Coral reefs
- Mayan ruins
- Beach clubs
- Day10
At Sea
- Day11

Miami, Florida
Arrive 07:00 · Depart 17:00
The cruise capital of the world — Miami sends more ships to sea than any port on earth. Most sailings board mid-afternoon, leaving the morning for South Beach, Little Havana or the Wynwood murals before you cast off.
- South Beach
- Little Havana
- Wynwood murals
Upcoming departures
- 15 Mar 2028
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
10-Night Americas Cruise from Panama City FAQ
Which ports does this cruise visit?
This 10-night Americas cruise calls at Panama City, Panama Canal Transit, At Sea, Puerto Limón, Roatán Island, Santo Tomás de Castilla, Costa Maya, Cozumel and Miami, Florida.
How many days are spent at sea?
3 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Panama City and ends in Miami, Florida.
How long is this cruise?
10 nights aboard Oceania Marina.
When does this itinerary sail?
Upcoming departures include 15 Mar 2028. A NestCruise advisor can confirm current availability.