South America cruises
868 live sailings explore South America — 5 to 21 nights, departing 58 ports, across 18 lines. A NestCruise advisor narrows them to the one that fits.
CaribbeanMSC Cruises
3 nights: Nassau, the Caribbean
Aboard MSC Seashore
Round-trip from Port Canaveral
CaribbeanRoyal Caribbean International
5 nights: Cozumel, the Caribbean
Aboard Radiance of the Seas
Round-trip from Tampa
from$298pp · cruise fare≈ $60/night pp
Fares checked nightly
CaribbeanMSC Cruises
7 nights: Cozumel, the Caribbean
Aboard MSC Seascape
Round-trip from Galveston
CaribbeanMSC Cruises
3 nights: Nassau, the Caribbean
Aboard MSC Seaside
Round-trip from Miami
CaribbeanRoyal Caribbean International
4 nights: Cozumel, the Caribbean
Aboard Liberty of the Seas
Round-trip from Galveston
from$349pp · cruise fare≈ $87/night pp
Fares checked nightly
CaribbeanRoyal Caribbean International
7 nights: Cozumel, the Caribbean
Aboard Enchantment of the Seas
Round-trip from Tampa
from$277pp · cruise fare≈ $40/night pp
Fares checked nightly
CaribbeanMSC Cruises
7 nights: Nassau & Cozumel, the Caribbean
Aboard MSC Grandiosa
Round-trip from Port Canaveral
CaribbeanRoyal Caribbean International
7 nights: Cozumel, the Caribbean
Aboard Symphony of the Seas
Round-trip from Galveston
from$588pp · cruise fare≈ $84/night pp
Fares checked nightly
CaribbeanMSC Cruises
6 nights: Cozumel, the Caribbean
Aboard MSC World America
Round-trip from Miami
CaribbeanRoyal Caribbean International
4 nights: Cozumel, the Caribbean
Aboard Jewel of the Seas
Round-trip from Tampa
from$307pp · cruise fare≈ $77/night pp
Fares checked nightly
South AmericaAmaWaterways
7 nights in South America
Aboard AmaMagdalena
Barranquilla → Cartagena
from$3,399pp · cruise fare≈ $486/night pp
Fares checked nightly
CaribbeanRoyal Caribbean International
7 nights: Cozumel, the Caribbean
Aboard Star of the Seas
Round-trip from Port Canaveral
from$897pp · cruise fare≈ $128/night pp
Fares checked nightly
South AmericaAmaWaterways
6 nights in South America
Aboard AmaMelodia
Barranquilla → Cartagena
from$3,299pp · cruise fare≈ $550/night pp
Fares checked nightly
CaribbeanRoyal Caribbean International
The Caribbean loop
Aboard Adventure of the Seas
Round-trip from Port Canaveral
from$458pp · cruise fare≈ $92/night pp
Fares checked nightly
CaribbeanMSC Cruises
13 nights: Cozumel & Nassau, the Caribbean
Aboard MSC World Atlantic
Round-trip from Port Canaveral
AmericasMSC Cruises
The South America loop
Aboard MSC Virtuosa
Round-trip from Salvador de Bahia
CaribbeanRoyal Caribbean International
7 nights in the Caribbean
Aboard Icon of the Seas
Western Caribbean
from$1,038pp · cruise fare≈ $148/night pp
Fares checked nightly
CaribbeanRoyal Caribbean International
7 nights: Cozumel, the Caribbean
Aboard Brilliance of the Seas
Round-trip from Tampa
from$625pp · cruise fare≈ $89/night pp
Fares checked nightly
CaribbeanRoyal Caribbean International
6 nights: Cozumel, the Caribbean
Aboard Serenade of the Seas
Round-trip from Tampa
from$484pp · cruise fare≈ $81/night pp
Fares checked nightly
CaribbeanMSC Cruises
The Caribbean loop
Aboard MSC Poesia
Round-trip from Miami
CaribbeanCelebrity Cruises
6 nights: Nassau, the Caribbean
Aboard Celebrity Beyond
Round-trip from Miami
from$690pp · cruise fare≈ $115/night pp
Fares checked nightly
CaribbeanRoyal Caribbean International
6 nights: Cozumel, the Caribbean
Aboard Legend of the Seas
Round-trip from Fort Lauderdale
from$1,005pp · cruise fare≈ $168/night pp
Fares checked nightly
CaribbeanMSC Cruises
6 nights: Nassau, the Caribbean
Aboard MSC Meraviglia
Round-trip from Miami
AmericasMSC Cruises
The South America loop
Aboard MSC Musica
Round-trip from Santos
CaribbeanCarnival Cruise Line
The Caribbean loop
Aboard Carnival Firenze
Round-trip from New York
from$447pp · cruise fare≈ $112/night pp
Fares checked nightly
CaribbeanRoyal Caribbean International
5 nights: Cozumel, the Caribbean
Aboard Freedom of the Seas
Round-trip from Miami
from$328pp · cruise fare≈ $66/night pp
Fares checked nightly
CaribbeanRoyal Caribbean International
7 nights in the Caribbean
Aboard Hero of the Seas
Perfect Day CocoCay & Western Caribbean
from$1,478pp · cruise fare≈ $211/night pp
Fares checked nightly
CaribbeanCelebrity Cruises
7 nights: Cozumel, the Caribbean
Aboard Celebrity Summit
Round-trip from Tampa
from$545pp · cruise fare≈ $78/night pp
Fares checked nightly
CaribbeanEmerald Cruises
The Caribbean loop
Aboard Emerald Sakara
Round-trip from Philipsburg
CaribbeanRoyal Caribbean International
7 nights: Cozumel & Nassau, the Caribbean
Aboard Harmony of the Seas
Round-trip from Port Canaveral
from$901pp · cruise fare≈ $129/night pp
Fares checked nightly
AmericasMSC Cruises
The South America loop
Aboard MSC Divina
Round-trip from Santos
CaribbeanVirgin Voyages
The Caribbean loop
Aboard Valiant Lady
Round-trip from Miami
from$1,272pp · cruise fare≈ $318/night pp
Fares checked nightly
CaribbeanVirgin Voyages
The Caribbean loop
Aboard Resilient Lady
Round-trip from Miami
from$1,490pp · cruise fare≈ $248/night pp
Fares checked nightly
CaribbeanRoyal Caribbean International
7 nights: Nassau, the Caribbean
Aboard Allure of the Seas
Round-trip from Miami
from$691pp · cruise fare≈ $99/night pp
Fares checked nightly
CaribbeanCarnival Cruise Line
7 nights: Nassau, the Caribbean
Aboard Carnival Breeze
Round-trip from Galveston
from$593pp · cruise fare≈ $85/night pp
Fares checked nightly
CaribbeanCelebrity Cruises
The Caribbean loop
Aboard Celebrity Apex
Round-trip from Port Canaveral
from$751pp · cruise fare≈ $107/night pp
Fares checked nightly
CaribbeanEmerald Cruises
The Caribbean loop
Aboard Emerald Azzurra
Round-trip from Bridgetown
CaribbeanEmerald Cruises
7 nights: San Juan, the Caribbean
Aboard Emerald Kaia
Saint John's → San Juan
CaribbeanRoyal Caribbean International
The Caribbean loop
Aboard Grandeur of the Seas
Round-trip from Cartagena
from$606pp · cruise fare≈ $87/night pp
Fares checked nightly
CaribbeanRoyal Caribbean International
7 nights: Nassau & Cozumel, the Caribbean
Aboard Independence Of The Seas
Round-trip from Miami
from$548pp · cruise fare≈ $78/night pp
Fares checked nightly
CaribbeanPONANT EXPLORATIONS
The Caribbean loop
Aboard Le Ponant
Round-trip from Pointe-à-Pitre
AmericasHolland America Line
7 nights: Cabo San Lucas, South America
Aboard Koningsdam
Round-trip from San Diego
AmericasMSC Cruises
7 nights: Buenos Aires, South America
Aboard MSC Seaview
Round-trip from Buenos Aires
CaribbeanMSC Cruises
The Caribbean loop
Aboard MSC World Europa
Round-trip from Pointe-à-Pitre
CaribbeanSilversea
The Caribbean loop
Aboard Silver Spirit
Round-trip from Bridgetown
from$2,950pp · cruise fare≈ $421/night pp
Fares checked nightly
CaribbeanCarnival Cruise Line
8 nights: Aruba, the Caribbean
Aboard Carnival Venezia
Round-trip from Port Canaveral
from$783pp · cruise fare≈ $98/night pp
Fares checked nightly
Frequently asked
- How many South America cruises does NestCruise have?
- 868 live sailings, 5 to 21 nights. A NestCruise advisor narrows them to the one that fits.
- Which cruise lines run South America cruises?
- Royal Caribbean International, MSC Cruises, Holland America Line and Carnival Cruise Line, among others.
- How long are South America cruises?
- Most run 5 to 21 nights.
- How much do South America cruises cost?
- NestCruise doesn't publish fares — it's a quote-only concierge. Share your dates and party size and an advisor prices your exact sailing at no cost.