Cruises to Puerto Quetzal
71 live cruises call at Puerto Quetzal — 15 to 127 nights, departing 15 ports, across 11 lines. A NestCruise advisor narrows them to the one that fits.
AmericasHolland America Line
16-Day Panama Canal
Aboard Eurodam
San Diego, California → Cabo San Lucas → Acapulco → Huatulco (Santa María Huatulco) +5 more
16 nights · 3 departures
Balanced · 9 ports
AmericasHolland America Line
14-Day Panama Canal
Aboard Zaandam
Fort Lauderdale, Florida → Cartagena → Quepos (Puerto Quepos) → Puerto Quetzal +4 more
14 nights · 2 departures
Balanced · 8 ports
RepositioningNorwegian Cruise Line
Panama Canal: Mexico & Costa Rica
Aboard Norwegian Encore
Los Angeles, California → Cabo San Lucas → Acapulco → Puerto Quetzal +5 more
15 nights · 2 departures
Balanced · 9 ports
RepositioningNorwegian Cruise Line
Panama Canal: Mexico & Costa Rica
Aboard Norwegian Joy
Miami, Florida → Cartagena → Colón → Córdoba +5 more
15 nights · 2 departures
Balanced · 9 ports
AmericasVirgin Voyages
Panama Canal: Miami to Los Angeles
Aboard Brilliant Lady
Miami, Florida → At Sea → Cartagena → Colón +5 more
16 nights · 2 departures
Balanced · 9 ports
RepositioningNorwegian Cruise Line
Panama Canal: Mexico & Costa Rica
Aboard Norwegian Bliss
New York, New York → Puerto Plata → Cartagena → Colón +7 more
19 nights · 2 departures
Balanced · 11 ports
AmericasHolland America Line
21-Day Panama Canal
Aboard Nieuw Amsterdam
Vancouver, British Columbia → San Francisco, California → San Diego, California → Puerto Vallarta +7 more
21 nights · 2 departures
Balanced · 11 ports
AmericasExplora Journeys
A Journey of Mayan Discovery & Mexican Exploration
Aboard EXPLORA III
Panama City → At Sea → Acajutla → Puerto Quetzal +4 more
11 nights · 1 departure
Balanced · 8 ports
CaribbeanRegent Seven Seas Cruises
Sapphire Sojourn
Aboard Seven Seas Prestige
Los Angeles, California → Cruising the Pacific Ocean → Cabo San Lucas → Mazatlán +4 more
12 nights · 1 departure
Balanced · 8 ports
AmericasHolland America Line
14-Day Panama Canal
Aboard Zuiderdam
Miami, Florida → Cartagena → Puntarenas → Puerto Quetzal +4 more
14 nights · 1 departure
Balanced · 8 ports
AmericasHolland America Line
15-Day Panama Canal
Aboard Oosterdam
Fort Lauderdale, Florida → Aruba → Puntarenas → Puerto Quetzal +3 more
15 nights · 1 departure
Sea-paced · 7 ports
AmericasRoyal Caribbean International
15 Night Panama Canal Eastward Cruise
Aboard Serenade of the Seas
San Diego, California → Puerto Vallarta → Puerto Quetzal → Puntarenas +4 more
15 nights · 1 departure
Balanced · 8 ports
AmericasOceania Cruises
Treasures Of Two Oceans
Aboard Oceania Vista
Miami, Florida → At Sea → Georgetown, Grand Cayman → Cartagena +6 more
15 nights · 1 departure
Balanced · 10 ports
AmericasNorwegian Cruise Line
Panama Canal: Mexico & Costa Rica
Aboard Norwegian Star
Miami, Florida → Cartagena → Colón → Córdoba +6 more
16 nights · 1 departure
Balanced · 10 ports
AmericasOceania Cruises
Panama Canal Coastlines
Aboard Oceania Sonata
Los Angeles, California → Ensenada → At Sea → Cabo San Lucas +7 more
16 nights · 1 departure
Balanced · 11 ports
AmericasRegent Seven Seas Cruises
Ultimate Panama Canal Transit
Aboard Seven Seas Grandeur
Los Angeles, California → Cruising the Pacific Ocean → Cabo San Lucas → Puerto Vallarta +8 more
16 nights · 1 departure
Balanced · 12 ports
AmericasRegent Seven Seas Cruises
Holiday In Panama
Aboard Seven Seas Splendor
Miami, Florida → Cruising the Bahamian Waters → Ocho Rios → Cruising the Caribbean Sea +8 more
16 nights · 1 departure
Balanced · 12 ports
AmericasAzamara
Panama Canal & Latin America Cruise: Mexico, Costa Rica & Colombia
Aboard Azamara Quest
San Diego, California → Cabo San Lucas → Acapulco → Puerto Quetzal +5 more
17 nights · 1 departure
Balanced · 9 ports
AmericasCelebrity Cruises
17 Night Panama Canal Eastbound Cruise
Aboard Celebrity Summit
Los Angeles, California → Puerto Vallarta → Puerto Quetzal → Puntarenas +5 more
17 nights · 1 departure
Balanced · 9 ports
CaribbeanSilversea
Miami to Los Angeles
Aboard Silver Dawn
Miami, Florida → At Sea → Cartagena → Panama Canal Transit +5 more
18 nights · 1 departure
Sea-paced · 9 ports
AmericasSeabourn
19-Day World Cruise: Panama Canal Crossing
Aboard Seabourn Quest
Long Beach, California → Puerto Vallarta → Huatulco (Santa María Huatulco) → Puerto Chiapas +4 more
19 nights · 1 departure
Sea-paced · 8 ports
AmericasOceania Cruises
Grand South America Adventure
Aboard Oceania Aurelia
Miami, Florida → At Sea → Charlotte Amalie → Tortola +41 more
71 nights · 1 departure
Balanced · 45 ports
AmericasHolland America Line
20-Day Panama Canal
Aboard Eurodam
Vancouver, British Columbia → Santa Barbara, California → San Diego, California → Cabo San Lucas +7 more
20 nights · 3 departures
Balanced · 11 ports
AmericasHolland America Line
15-Day Panama Canal Holiday
Aboard Zaandam
San Diego, California → Cabo San Lucas → Puerto Vallarta → Huatulco (Santa María Huatulco) +4 more
15 nights · 2 departures
Balanced · 8 ports
RepositioningNorwegian Cruise Line
Panama Canal: Mexico, Costa Rica & Colombia
Aboard Norwegian Joy
Los Angeles, California → Cabo San Lucas → Acapulco → Puerto Quetzal +6 more
16 nights · 1 departure
Balanced · 10 ports
AmericasVirgin Voyages
Panama Canal: LA to Miami Halloween
Aboard Brilliant Lady
Los Angeles, California → At Sea → Cabo San Lucas → Puerto Quetzal +5 more
17 nights · 1 departure
Balanced · 9 ports
RepositioningNorwegian Cruise Line
Panama Canal: Mexico & Costa Rica
Aboard Norwegian Bliss
New York, New York → Puerto Plata → Cartagena → Colón +9 more
22 nights · 2 departures
Balanced · 13 ports
AmericasHolland America Line
16-Day Panama Canal
Aboard Nieuw Amsterdam
San Diego, California → Puerto Vallarta → Huatulco (Santa María Huatulco) → Puerto Chiapas +5 more
16 nights · 1 departure
Balanced · 9 ports
PacificExplora Journeys
An Extended Journey of Ancient Mysteries & Pacific Coastal Wonders
Aboard EXPLORA III
Panama City → At Sea → Acajutla → Puerto Quetzal +8 more
18 nights · 1 departure
Balanced · 12 ports
AmericasRegent Seven Seas Cruises
Celestial Tropics
Aboard Seven Seas Prestige
Miami, Florida → Cruising the Florida Straits → Georgetown, Grand Cayman → Cruising the Caribbean Sea +7 more
15 nights · 1 departure
Balanced · 11 ports
AmericasHolland America Line
15-Day Panama Canal
Aboard Zuiderdam
San Diego, California → Puerto Vallarta → Huatulco (Santa María Huatulco) → Puerto Chiapas +5 more
15 nights · 1 departure
Balanced · 9 ports
AmericasHolland America Line
21-Day Panama Canal
Aboard Oosterdam
Fort Lauderdale, Florida → Aruba → Puntarenas → Puerto Quetzal +6 more
21 nights · 1 departure
Sea-paced · 10 ports
AmericasOceania Cruises
Transamerican Treasures
Aboard Oceania Vista
Miami, Florida → At Sea → Georgetown, Grand Cayman → Cartagena +8 more
18 nights · 1 departure
Balanced · 12 ports
RepositioningNorwegian Cruise Line
Panama Canal: Mexico & Colombia
Aboard Norwegian Star
San Diego, California → Cabo San Lucas → Acapulco → Puerto Quetzal +6 more
16 nights · 1 departure
Balanced · 10 ports
AmericasOceania Cruises
Halcyon Holidays
Aboard Oceania Sonata
Miami, Florida → At Sea → Georgetown, Grand Cayman → Cartagena +7 more
16 nights · 1 departure
Balanced · 11 ports
AmericasRegent Seven Seas Cruises
Panama Canal & Pacific Gems
Aboard Seven Seas Grandeur
Miami, Florida → Cruising the Florida Straits → Georgetown, Grand Cayman → Cruising the Caribbean Sea +9 more
16 nights · 1 departure
Port-rich · 13 ports
PacificRegent Seven Seas Cruises
Canal To Coral Reefs
Aboard Seven Seas Splendor
Panama City → Cruising the Pacific Ocean → Puntarenas → Acajutla +10 more
28 nights · 1 departure
Balanced · 14 ports
AmericasAzamara
Panama Canal Holiday Cruise: Miami, Cabo Rojo & San Diego
Aboard Azamara Quest
Miami, Florida → Cabo Rojo → Cartagena → Panama Canal Transit +5 more
18 nights · 1 departure
Sea-paced · 9 ports
AmericasCelebrity Cruises
18 Night Panama Canal Eastbound Cruise
Aboard Celebrity Summit
Los Angeles, California → Puerto Vallarta → Puerto Quetzal → Puntarenas +4 more
18 nights · 1 departure
Sea-paced · 8 ports
World CruiseSeabourn
27-Day World Cruise: Hawaii & Panama Canal
Aboard Seabourn Quest
Honolulu, Hawaii → Kailua-Kona, Hawaii → Long Beach, California → Puerto Vallarta +6 more
27 nights · 1 departure
Sea-paced · 10 ports
World CruiseOceania Cruises
Around The World In 180 Days
Aboard Oceania Aurelia
Los Angeles, California → At Sea → Cabo San Lucas → Zihuatanejo +98 more
181 nights · 1 departure
Balanced · 102 ports
AmericasHolland America Line
21-Day Panama Canal
Aboard Eurodam
Seattle, Washington → Vancouver, British Columbia → Santa Barbara, California → San Diego, California +8 more
21 nights · 3 departures
Balanced · 12 ports
AmericasNorwegian Cruise Line
Panama Canal: Mexico & Jamaica
Aboard Norwegian Joy
Los Angeles, California → Cabo San Lucas → Acapulco → Puerto Quetzal +7 more
17 nights · 1 departure
Balanced · 11 ports
RepositioningNorwegian Cruise Line
Panama Canal: Mexico & Jamaica
Aboard Norwegian Bliss
Los Angeles, California → Cabo San Lucas → Acapulco → Puerto Quetzal +6 more
16 nights · 1 departure
Balanced · 10 ports
AmericasHolland America Line
17-Day Panama Canal
Aboard Nieuw Amsterdam
Fort Lauderdale, Florida → Aruba → Puntarenas → Acajutla +5 more
17 nights · 1 departure
Balanced · 9 ports
CaribbeanExplora Journeys
An Extended Journey from Majestic Horizons to Mayan Gems
Aboard EXPLORA III
Miami, Florida → At Sea → Ocho Rios → Willemstad +11 more
21 nights · 1 departure
Balanced · 15 ports
Frequently asked
- How many cruises to Puerto Quetzal does NestCruise have?
- 71 live sailings, 15 to 127 nights. A NestCruise advisor narrows them to the one that fits.
- Which cruise lines visit Puerto Quetzal?
- Holland America Line, Oceania Cruises, Norwegian Cruise Line and Regent Seven Seas Cruises, among others.
- How long are cruises to Puerto Quetzal?
- Most run 15 to 127 nights.
- How much do cruises to Puerto Quetzal cost?
- NestCruise doesn't publish fares — it's a quote-only concierge. Share your dates and party size and an advisor prices your exact sailing at no cost.