Cruise itinerary
16-Night Americas Cruise from Miami, Florida
16 nights · Americas · 10 ports of call
16-night Americas cruise aboard Norwegian Star, departing Miami, Florida and calling at Cartagena, Colón, Transit Panama Canal, Puntarenas, Puerto Quetzal and Acapulco and 3 more.
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- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Norwegian Star
- Cruise line
- Norwegian Cruise Line
- Duration
- 16 nights
- Region
- Americas · South America · Panama Canal
- Departs
- Miami, Florida
- Returns
- San Diego, California
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Norwegian Star sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1
Miami, Florida
Depart 16:00
The cruise capital of the world — Miami sends more ships to sea than any port on earth. Most sailings board mid-afternoon, leaving the morning for South Beach, Little Havana or the Wynwood murals before you cast off.
- South Beach
- Little Havana
- Wynwood murals
- Day2At sea
- Day3At sea
- Day4
Cartagena
Arrive 08:00 · Depart 17:00
A walled colonial city on Colombia's Caribbean coast, its old town a maze of pastel houses, balconies and shaded plazas. Massive stone ramparts ring the centre, with the San Felipe fortress guarding the harbour above.
- Walled old town
- San Felipe fortress
- Plaza Santo Domingo
- Day5
Colón
Arrive 10:00 · Depart 22:00
A Caribbean port at the Atlantic entrance to the Panama Canal, the usual landing for ships transiting or calling at the isthmus. The historic Gatún Locks and rainforest waterways lie close by, along with the duty-free trade zone and the old fortifications of Portobelo.
- Gatún Locks
- Panama Canal
- Portobelo forts
- Day6
Transit Panama Canal
- Day7At sea
- Day8
Puntarenas
Arrive 07:00 · Depart 17:00
A Pacific port city on a narrow sandy spit on Costa Rica's central coast. It serves chiefly as a gateway inland to rainforests and volcanoes, with a long beachfront promenade and boats out to the Gulf of Nicoya's islands.
- Gulf of Nicoya
- Beachfront paseo
- Rainforest gateway
- Day9At sea
- Day10
Puerto Quetzal
Arrive 07:00 · Depart 17:00
Guatemala's main Pacific port, a working harbour backed by volcanic highlands. It opens the way to colonial Antigua with its cobbled streets and ruined convents, the coffee farms on the slopes and Lake Atitlán's volcano-ringed shore.
- Antigua Guatemala
- Lake Atitlán
- Coffee plantations
- Day11At sea
- Day12
Acapulco
Arrive 07:00 · Depart 17:00
- Day13At sea
- Day14
Puerto Vallarta
Arrive 07:00 · Depart 15:00
A resort city on Mexico's Pacific coast, set where the Sierra Madre meets Banderas Bay. Its cobbled Zona Romántica and the seaside Malecón promenade anchor an old town of churches and galleries, with whale-watching in the bay through the winter months.
- The Malecón
- Zona Romántica
- Banderas Bay
- Day15
Cabo San Lucas
Arrive 07:30 · Depart 14:30
A resort town at the southern tip of Mexico's Baja California peninsula, where the desert meets the Pacific and Sea of Cortez. Cabo San Lucas is known for its rock arch at Land's End, sport fishing, and the marina lined with restaurants and boats.
- El Arco
- Lover's Beach
- Cabo marina
- Day16At sea
- Day17
San Diego, California
Arrive 07:00
A relaxed harbour city in southern California, known for its mild climate and broad natural bay. The waterfront holds the historic Gaslamp Quarter and maritime museums, with the green expanse of Balboa Park and its zoo just inland.
- Balboa Park
- Gaslamp Quarter
- San Diego Zoo
Upcoming departures
- 4 Dec 2026
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
16-Night Americas Cruise from Miami, Florida FAQ
Which ports does this cruise visit?
This 16-night Americas cruise calls at Miami, Florida, Cartagena, Colón, Transit Panama Canal, Puntarenas, Puerto Quetzal, Acapulco, Puerto Vallarta, Cabo San Lucas and San Diego, California.
How many days are spent at sea?
7 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Miami, Florida and ends in San Diego, California.
How long is this cruise?
16 nights aboard Norwegian Star.
When does this itinerary sail?
Upcoming departures include 4 Dec 2026. A NestCruise advisor can confirm current availability.