Cruise itinerary
21-Night Americas Cruise from Vancouver, British Columbia
21 nights · Americas · 11 ports of call
21-night Americas cruise aboard Nieuw Amsterdam, departing Vancouver, British Columbia and calling at San Francisco, California, San Diego, California, Puerto Vallarta, Huatulco (Santa María Huatulco), Puerto Chiapas and Puerto Quetzal and 4 more.
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At a glance
- Ship
- Nieuw Amsterdam
- Cruise line
- Holland America Line
- Duration
- 21 nights
- Region
- Americas · South America · Panama Canal
- Departs
- Vancouver, British Columbia
- Returns
- Fort Lauderdale, Florida
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Nieuw Amsterdam sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1
Vancouver, British Columbia
Depart 16:00
A Pacific coast city in British Columbia and the main homeport for Alaska cruises. Ships sail from beneath the sails of Canada Place, with Stanley Park's seawall, the totem poles and the cobbled Gastown district close to the terminal.
- Stanley Park
- Gastown
- Gateway to Alaska
- Day2At sea
- Day3At sea
- Day4
San Francisco, California
Arrive 07:00 · Depart 21:00
A hill-built city on a peninsula between the Pacific and San Francisco Bay, known for the Golden Gate Bridge, cable cars, and Victorian rowhouses. Ships dock near the Embarcadero, within reach of Fisherman's Wharf, Chinatown, and ferries to Alcatraz.
- Golden Gate Bridge
- Cable cars
- Alcatraz Island
- Day5At sea
- Day6
San Diego, California
Arrive 07:00 · Depart 16:00
A relaxed harbour city in southern California, known for its mild climate and broad natural bay. The waterfront holds the historic Gaslamp Quarter and maritime museums, with the green expanse of Balboa Park and its zoo just inland.
- Balboa Park
- Gaslamp Quarter
- San Diego Zoo
- Day7At sea
- Day8At sea
- Day9
Puerto Vallarta
Arrive 08:00 · Depart 17:00
A resort city on Mexico's Pacific coast, set where the Sierra Madre meets Banderas Bay. Its cobbled Zona Romántica and the seaside Malecón promenade anchor an old town of churches and galleries, with whale-watching in the bay through the winter months.
- The Malecón
- Zona Romántica
- Banderas Bay
- Day10At sea
- Day11
Huatulco (Santa María Huatulco)
Arrive 10:00 · Depart 17:00
- Day12
Puerto Chiapas
Arrive 08:00 · Depart 17:00
- Day13
Puerto Quetzal
Arrive 06:00 · Depart 20:00
Guatemala's main Pacific port, a working harbour backed by volcanic highlands. It opens the way to colonial Antigua with its cobbled streets and ruined convents, the coffee farms on the slopes and Lake Atitlán's volcano-ringed shore.
- Antigua Guatemala
- Lake Atitlán
- Coffee plantations
- Day14
Acajutla
Arrive 07:00 · Depart 17:00
- Day15At sea
- Day16At sea
- Day17At sea
- Day18
Cartagena
Arrive 12:00 · Depart 18:00
A walled colonial city on Colombia's Caribbean coast, its old town a maze of pastel houses, balconies and shaded plazas. Massive stone ramparts ring the centre, with the San Felipe fortress guarding the harbour above.
- Walled old town
- San Felipe fortress
- Plaza Santo Domingo
- Day19At sea
- Day20At sea
- Day21
Half Moon Cay
Arrive 08:00 · Depart 14:00
A private island in the Bahamas used by cruise lines as a beach day, set on a crescent of pale sand and shallow turquoise water. The day centres on swimming, watersports, a horseshoe lagoon and a barbecue lunch ashore.
- Crescent beach
- Stingray lagoon
- Watersports
- Day22
Fort Lauderdale, Florida
Arrive 07:00
A South Florida port often called the yachting capital, fringed by canals and the long sands of Fort Lauderdale Beach. Port Everglades is among the world's busiest cruise gateways, with Las Olas Boulevard's shops and cafés minutes from the piers.
- Port Everglades
- Las Olas Boulevard
- Fort Lauderdale Beach
Upcoming departures
- 27 Sep 2026
- 11 Apr 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
21-Night Americas Cruise from Vancouver, British Columbia FAQ
Which ports does this cruise visit?
This 21-night Americas cruise calls at Vancouver, British Columbia, San Francisco, California, San Diego, California, Puerto Vallarta, Huatulco (Santa María Huatulco), Puerto Chiapas, Puerto Quetzal, Acajutla, Cartagena, Half Moon Cay and Fort Lauderdale, Florida.
How many days are spent at sea?
11 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Vancouver, British Columbia and ends in Fort Lauderdale, Florida.
How long is this cruise?
21 nights aboard Nieuw Amsterdam.
When does this itinerary sail?
Upcoming departures include 27 Sep 2026 and 11 Apr 2027. A NestCruise advisor can confirm current availability.