Cruises from Panama City
12 live cruises sail from Panama City — 10 to 26 nights, across 4 lines, through Americas. A NestCruise advisor narrows them to the one that fits.
AmericasEmerald Cruises
7 nights in South America
Aboard Emerald Azzurra
Panama City → Puerto Caldera
AmericasOceania Cruises
10 nights in South America
Aboard Oceania Marina
Panama City → Miami
Central & North America Pacific CoastExplora Journeys
11 nights: Puerto Vallarta & Vancouver
Aboard EXPLORA III
Panama City → Vancouver
AmericasRegent Seven Seas Cruises
11 nights: Cozumel, South America
Aboard Seven Seas Prestige
Panama City → Miami
AmericasRegent Seven Seas Cruises
14 nights in South America
Aboard Seven Seas Grandeur
Panama City → Miami
PacificRegent Seven Seas Cruises
28 nights: Cabo San Lucas & Honolulu
Aboard Seven Seas Splendor
Panama City → Papeete
AmericasEmerald Cruises
11 nights in South America
Aboard Emerald Azzurra
Panama City → Bridgetown
AmericasOceania Cruises
10 nights: Cozumel, South America
Aboard Oceania Marina
Panama City → Miami
AmericasRegent Seven Seas Cruises
12 nights in South America
Aboard Seven Seas Prestige
Panama City → Miami
AmericasRegent Seven Seas Cruises
The South America loop
Aboard Seven Seas Grandeur
Round-trip from Panama City
Frequently asked
- How many cruises from Panama City does NestCruise have?
- 12 live sailings, 10 to 26 nights. A NestCruise advisor narrows them to the one that fits.
- Which cruise lines sail from Panama City?
- Regent Seven Seas Cruises, Oceania Cruises, Emerald Cruises and Explora Journeys, among others.
- How long are cruises from Panama City?
- Most run 10 to 26 nights.
- How much do cruises from Panama City cost?
- NestCruise doesn't publish fares — it's a quote-only concierge. Share your dates and party size and an advisor prices your exact sailing at no cost.