How many cruises from Panama City does NestCruise have?

12 live sailings, 10 to 26 nights. A NestCruise advisor narrows them to the one that fits.

Which cruise lines sail from Panama City?

Regent Seven Seas Cruises, Oceania Cruises, Emerald Cruises and Explora Journeys, among others.

How much do cruises from Panama City cost?

NestCruise doesn't publish fares — it's a quote-only concierge. Share your dates and party size and an advisor prices your exact sailing at no cost.

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Cruises from Panama City

12 live cruises sail from Panama City — 10 to 26 nights, across 4 lines, through Americas. A NestCruise advisor narrows them to the one that fits.

12 sailings

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Americas

Emerald Cruises

7 nights in South America

Aboard Emerald Azzurra

Panama City → Puerto Caldera

↓ $597 this monthCaribbean Sale!

from$5,848pp · cruise fare≈ $835/night pp

Fares checked nightly

Jan 2028 – Jan 2029Next 24 Jan 2028 · 1 more

Americas

Oceania Cruises

10 nights in South America

Aboard Oceania Marina

Panama City → Miami

Rare itinerary

Jan 2028 – Mar 2028Next 16 Jan 2028 · 1 more

Central & North America Pacific Coast

Explora Journeys

11 nights: Puerto Vallarta & Vancouver

Aboard EXPLORA III

Panama City → Vancouver

↓ $3,025 this monthWinter 2026-2027

from$6,075pp · cruise fare≈ $552/night pp

Fares checked nightly

Apr 2027Next 22 Apr 2027

Americas

Regent Seven Seas Cruises

11 nights: Cozumel, South America

Aboard Seven Seas Prestige

Panama City → Miami

↓ $17,599 this monthBonus Savings of

from$11,599pp · cruise fare≈ $1,054/night pp

Fares checked nightly

Feb 2027Next 22 Feb 2027

Americas

Regent Seven Seas Cruises

14 nights in South America

Aboard Seven Seas Grandeur

Panama City → Miami

Overnight in Panama CityRare itinerary

Mar 2027Next 31 Mar 2027

Pacific

Regent Seven Seas Cruises

28 nights: Cabo San Lucas & Honolulu

Aboard Seven Seas Splendor

Panama City → Papeete

↓ $30,199 this monthBonus Savings of

from$21,799pp · cruise fare≈ $779/night pp

Fares checked nightly

Jan 2027Next 26 Jan 2027

Panama Canal transit, Colombia & the Grenadines

Americas

Emerald Cruises

11 nights in South America

Aboard Emerald Azzurra

Panama City → Bridgetown

↓ $404 this monthIncludes Preferred Savings

from$8,841pp · cruise fare≈ $804/night pp

Fares checked nightly

Feb 2028 – Mar 2029Next 29 Feb 2028 · 1 more

Americas

Oceania Cruises

10 nights: Cozumel, South America

Aboard Oceania Marina

Panama City → Miami

Rare itinerary

Mar 2028Next 15 Mar 2028

Americas

Regent Seven Seas Cruises

12 nights in South America

Aboard Seven Seas Prestige

Panama City → Miami

↓ $13,699 this monthBonus Savings of

from$7,699pp · cruise fare≈ $642/night pp

Fares checked nightly

Mar 2028Next 14 Mar 2028

Americas

Regent Seven Seas Cruises

The South America loop

Aboard Seven Seas Grandeur

Round-trip from Panama City

↓ $29,999 this monthBonus Savings of

from$23,799pp · cruise fare≈ $1,082/night pp

Fares checked nightly

Mar 2027Next 9 Mar 2027

Americas

Oceania Cruises

10 nights in South America

Aboard Oceania Marina

Panama City → Miami

Overnight in Panama CityRare itinerary

Jan 2027Next 15 Jan 2027

Americas

Regent Seven Seas Cruises

26 nights in South America

Aboard Seven Seas Prestige

Panama City → Lisbon

↓ $29,999 this monthBonus Savings of

from$16,999pp · cruise fare≈ $654/night pp

Fares checked nightly

Mar 2028Next 14 Mar 2028

Frequently asked

How many cruises from Panama City does NestCruise have?: 12 live sailings, 10 to 26 nights. A NestCruise advisor narrows them to the one that fits.
Which cruise lines sail from Panama City?: Regent Seven Seas Cruises, Oceania Cruises, Emerald Cruises and Explora Journeys, among others.
How long are cruises from Panama City?: Most run 10 to 26 nights.
How much do cruises from Panama City cost?: NestCruise doesn't publish fares — it's a quote-only concierge. Share your dates and party size and an advisor prices your exact sailing at no cost.