Panama Canal cruises
90 live sailings explore Panama Canal — 10 to 22 nights, departing 18 ports, across 14 lines. A NestCruise advisor narrows them to the one that fits.
AmericasCelebrity Cruises
The South America loop
Aboard Celebrity Ascent
Round-trip from Fort Lauderdale
from$1,174pp · cruise fare≈ $107/night pp
Fares checked nightly
AmericasHolland America Line
12 nights: Aruba & Grand Cayman, South America
Aboard Nieuw Amsterdam
Round-trip from Fort Lauderdale
AmericasHolland America Line
12 nights: Aruba & Grand Cayman, South America
Aboard Oosterdam
Round-trip from Fort Lauderdale
AmericasCarnival Cruise Line
16 nights: Seattle & Cabo San Lucas, South America
Aboard Carnival Spirit
Seattle → Mobile
from$901pp · cruise fare≈ $56/night pp
Fares checked nightly
AmericasHolland America Line
16 nights: Cabo San Lucas & Aruba, South America
Aboard Eurodam
San Diego → Fort Lauderdale
CaribbeanEmerald Cruises
18 nights in the Caribbean
Aboard Emerald Azzurra
Bridgetown → Puerto Caldera
from$17,540pp · cruise fare≈ $974/night pp
Fares checked nightly
AmericasOceania Cruises
10 nights in South America
Aboard Oceania Marina
Panama City → Miami
Panama CanalNorwegian Cruise Line
The Panama Canal transit
Aboard Norwegian Gem
Round-trip from Miami
from$1,439pp · cruise fare≈ $144/night pp
Fares checked nightly
AmericasHolland America Line
14 nights: Puerto Vallarta & Cabo San Lucas, South America
Aboard Zaandam
Fort Lauderdale → San Diego
Panama CanalNorwegian Cruise Line
15 nights: Cabo San Lucas, the Panama Canal
Aboard Norwegian Encore
Los Angeles → Miami
from$1,829pp · cruise fare≈ $122/night pp
Fares checked nightly
AmericasVirgin Voyages
16 nights: Cabo San Lucas, South America
Aboard Brilliant Lady
Miami → Los Angeles
from$4,046pp · cruise fare≈ $253/night pp
Fares checked nightly
Panama CanalMSC Cruises
18 nights: Cabo San Lucas & Seattle, the Panama Canal
Aboard MSC Poesia
Miami → Seattle
Panama CanalNorwegian Cruise Line
19 nights: Puerto Vallarta & Cabo San Lucas, the Panama Canal
Aboard Norwegian Bliss
New York → Seattle
from$2,419pp · cruise fare≈ $127/night pp
Fares checked nightly
AmericasAzamara
9 nights: Cozumel, South America
Aboard Azamara Quest
Miami → Fuerte Amador
from$3,529pp · cruise fare≈ $392/night pp
Fares checked nightly
CaribbeanRegent Seven Seas Cruises
10 nights: Cabo San Lucas & Puerto Vallarta, the Caribbean
Aboard Seven Seas Grandeur
Round-trip from Los Angeles
from$8,349pp · cruise fare≈ $835/night pp
Fares checked nightly
CaribbeanRegent Seven Seas Cruises
10 nights: Cabo San Lucas & Puerto Vallarta, the Caribbean
Aboard Seven Seas Prestige
Round-trip from Los Angeles
from$7,399pp · cruise fare≈ $740/night pp
Fares checked nightly
AmericasCrystal
14 nights in South America
Aboard Crystal Serenity
Fuerte Amador → New York
from$6,100pp · cruise fare≈ $436/night pp
Fares checked nightly
AmericasHolland America Line
14 nights: Cabo San Lucas, South America
Aboard Zuiderdam
Miami → San Diego
AmericasAzamara
14 nights in South America
Aboard Azamara Onward
Miami → Lima
from$5,309pp · cruise fare≈ $379/night pp
Fares checked nightly
AmericasRegent Seven Seas Cruises
14 nights: Cozumel, South America
Aboard Seven Seas Splendor
Miami → Panama City
AmericasRegent Seven Seas Cruises
14 nights in South America
Aboard Seven Seas Voyager
Miami → Callao
Panama CanalCelebrity Cruises
15 nights: Grand Cayman & Puerto Vallarta, the Panama Canal
Aboard Celebrity Summit
Tampa → Los Angeles
from$1,693pp · cruise fare≈ $113/night pp
Fares checked nightly
AmericasCrystal
15 nights: Juneau & Skagway, South America
Aboard Crystal Symphony
Fort Lauderdale → Vancouver
from$5,700pp · cruise fare≈ $380/night pp
Fares checked nightly
Panama CanalRoyal Caribbean International
15 nights: Puerto Vallarta & Grand Cayman, the Panama Canal
Aboard Serenade of the Seas
San Diego → Tampa
AmericasOceania Cruises
15 nights in South America
Aboard Oceania Vista
Miami → Los Angeles
AmericasCarnival Cruise Line
16 nights: Cabo San Lucas & Seattle, South America
Aboard Carnival Legend
Tampa → Seattle
from$1,046pp · cruise fare≈ $65/night pp
Fares checked nightly
Panama CanalNorwegian Cruise Line
16 nights: Puerto Vallarta & Cabo San Lucas, the Panama Canal
Aboard Norwegian Star
Miami → San Diego
AmericasOceania Cruises
16 nights: Ensenada & Cabo San Lucas, South America
Aboard Oceania Sonata
Los Angeles → Miami
Panama CanalSeabourn
19 nights in the Panama Canal
Aboard Seabourn Quest
19-Night World Cruise: Panama Canal Crossing
from$15,093pp · cruise fare≈ $794/night pp
Fares checked nightly
Panama CanalHX Expeditions
23 nights: Seattle, the Panama Canal
Aboard MS Fridtjof Nansen
New York → Seattle
Panama CanalHX Expeditions
23 nights: Seattle, the Panama Canal
Aboard MS Roald Amundsen
Seattle → New York
AmericasHolland America Line
21 nights: Vancouver & Puerto Vallarta, South America
Aboard Nieuw Amsterdam
Vancouver → Fort Lauderdale
AmericasHolland America Line
15 nights: Aruba & Cabo San Lucas, South America
Aboard Oosterdam
Fort Lauderdale → San Diego
AmericasHolland America Line
20 nights: Vancouver & Cabo San Lucas, South America
Aboard Eurodam
Vancouver → Fort Lauderdale
AmericasEmerald Cruises
11 nights in South America
Aboard Emerald Azzurra
Bridgetown → Panama City
from$8,841pp · cruise fare≈ $804/night pp
Fares checked nightly
AmericasOceania Cruises
10 nights: Cozumel, South America
Aboard Oceania Marina
Miami → Panama City
AmericasHolland America Line
15 nights: Cabo San Lucas & Puerto Vallarta, South America
Aboard Zaandam
San Diego → Fort Lauderdale
Panama CanalVirgin Voyages
17 nights: Cabo San Lucas, the Panama Canal
Aboard Brilliant Lady
Los Angeles → Miami
from$4,046pp · cruise fare≈ $238/night pp
Fares checked nightly
Panama CanalMSC Cruises
19 nights: Seattle & Cabo San Lucas, the Panama Canal
Aboard MSC Poesia
Seattle → Miami
Panama CanalNorwegian Cruise Line
17 nights: Cabo San Lucas, the Panama Canal
Aboard Norwegian Bliss
Los Angeles → New York
from$2,159pp · cruise fare≈ $127/night pp
Fares checked nightly
AmericasAzamara
10 nights in South America
Aboard Azamara Quest
Fuerte Amador → Valparaiso
from$3,059pp · cruise fare≈ $306/night pp
Fares checked nightly
AmericasRegent Seven Seas Cruises
14 nights in South America
Aboard Seven Seas Grandeur
Panama City → Miami
from$9,899pp · cruise fare≈ $707/night pp
Fares checked nightly
AmericasRegent Seven Seas Cruises
11 nights: Cozumel, South America
Aboard Seven Seas Prestige
Panama City → Miami
Panama CanalCrystal
25 nights in the Panama Canal
Aboard Crystal Serenity
San Diego to New York
from$10,400pp · cruise fare≈ $416/night pp
Fares checked nightly
AmericasHolland America Line
15 nights: Puerto Vallarta, South America
Aboard Zuiderdam
San Diego → Miami
AmericasRegent Seven Seas Cruises
16 nights: Puerto Vallarta & Cabo San Lucas, South America
Aboard Seven Seas Splendor
Miami → San Francisco
from$12,199pp · cruise fare≈ $762/night pp
Fares checked nightly
Frequently asked
- How many Panama Canal cruises does NestCruise have?
- 90 live sailings, 10 to 22 nights. A NestCruise advisor narrows them to the one that fits.
- Which cruise lines run Panama Canal cruises?
- Regent Seven Seas Cruises, Holland America Line, Oceania Cruises and Emerald Cruises, among others.
- How long are Panama Canal cruises?
- Most run 10 to 22 nights.
- How much do Panama Canal cruises cost?
- NestCruise doesn't publish fares — it's a quote-only concierge. Share your dates and party size and an advisor prices your exact sailing at no cost.