Panama Canal cruises
98 live sailings explore Panama Canal — 11 to 23 nights, departing 18 ports, across 14 lines. A NestCruise advisor narrows them to the one that fits.
AmericasCelebrity Cruises
The South America loop
Aboard Celebrity Ascent
Round-trip from Fort Lauderdale
from$1,130pp · cruise fare≈ $103/night pp
Fares checked nightly
AmericasHolland America Line
12 nights: Aruba & Grand Cayman, South America
Aboard Nieuw Amsterdam
Round-trip from Fort Lauderdale
from$1,164pp · cruise fare≈ $97/night pp
Fares checked nightly
AmericasHolland America Line
12 nights: Aruba & Grand Cayman, South America
Aboard Oosterdam
Round-trip from Fort Lauderdale
from$1,489pp · cruise fare≈ $124/night pp
Fares checked nightly
AmericasCarnival Cruise Line
16 nights: Seattle & Cabo San Lucas, South America
Aboard Carnival Spirit
Seattle → Mobile
from$495pp · cruise fare≈ $31/night pp
Fares checked nightly
AmericasHolland America Line
16 nights: Cabo San Lucas & Aruba, South America
Aboard Eurodam
San Diego → Fort Lauderdale
from$159pp · cruise fare≈ $10/night pp
Fares checked nightly
CaribbeanEmerald Cruises
18 nights in the Caribbean
Aboard Emerald Azzurra
Bridgetown → Puerto Caldera
AmericasOceania Cruises
10 nights in South America
Aboard Oceania Marina
Panama City → Miami
Panama CanalNorwegian Cruise Line
The Panama Canal transit
Aboard Norwegian Gem
Round-trip from Miami
from$1,439pp · cruise fare≈ $144/night pp
Fares checked nightly
AmericasHolland America Line
14 nights: Puerto Vallarta & Cabo San Lucas, South America
Aboard Zaandam
Fort Lauderdale → San Diego
from$899pp · cruise fare≈ $64/night pp
Fares checked nightly
Panama CanalNorwegian Cruise Line
15 nights: Cabo San Lucas, the Panama Canal
Aboard Norwegian Encore
Los Angeles → Miami
from$2,139pp · cruise fare≈ $143/night pp
Fares checked nightly
AmericasVirgin Voyages
16 nights: Cabo San Lucas, South America
Aboard Brilliant Lady
Miami → Los Angeles
from$834pp · cruise fare≈ $52/night pp
Fares checked nightly
Panama CanalMSC Cruises
18 nights: Cabo San Lucas & Seattle, the Panama Canal
Aboard MSC Poesia
Miami → Seattle
from$444pp · cruise fare≈ $25/night pp
Fares checked nightly
Panama CanalNorwegian Cruise Line
19 nights: Puerto Vallarta & Cabo San Lucas, the Panama Canal
Aboard Norwegian Bliss
New York → Seattle
from$849pp · cruise fare≈ $45/night pp
Fares checked nightly
AmericasAzamara
9 nights: Cozumel, South America
Aboard Azamara Quest
Miami → Fuerte Amador
from$4,239pp · cruise fare≈ $471/night pp
Fares checked nightly
CaribbeanRegent Seven Seas Cruises
10 nights: Cabo San Lucas & Puerto Vallarta, the Caribbean
Aboard Seven Seas Grandeur
Round-trip from Los Angeles
CaribbeanRegent Seven Seas Cruises
10 nights: Cabo San Lucas & Puerto Vallarta, the Caribbean
Aboard Seven Seas Prestige
Round-trip from Los Angeles
AmericasCrystal
14 nights in South America
Aboard Crystal Serenity
Fuerte Amador → New York
AmericasHolland America Line
14 nights: Cabo San Lucas, South America
Aboard Zuiderdam
Miami → San Diego
from$1,689pp · cruise fare≈ $121/night pp
Fares checked nightly
AmericasAzamara
14 nights in South America
Aboard Azamara Onward
Miami → Lima
from$6,439pp · cruise fare≈ $460/night pp
Fares checked nightly
AmericasRegent Seven Seas Cruises
14 nights: Cozumel, South America
Aboard Seven Seas Splendor
Miami → Panama City
AmericasRegent Seven Seas Cruises
14 nights in South America
Aboard Seven Seas Voyager
Miami → Callao
Panama CanalCelebrity Cruises
15 nights: Grand Cayman & Puerto Vallarta, the Panama Canal
Aboard Celebrity Summit
Tampa → Los Angeles
from$3,022pp · cruise fare≈ $201/night pp
Fares checked nightly
AmericasCrystal
15 nights: Juneau & Skagway, South America
Aboard Crystal Symphony
Fort Lauderdale → Vancouver
Panama CanalRoyal Caribbean International
15 nights: Puerto Vallarta & Grand Cayman, the Panama Canal
Aboard Serenade of the Seas
San Diego → Tampa
from$1,917pp · cruise fare≈ $128/night pp
Fares checked nightly
AmericasOceania Cruises
15 nights in South America
Aboard Oceania Vista
Miami → Los Angeles
AmericasCarnival Cruise Line
16 nights: Cabo San Lucas & Seattle, South America
Aboard Carnival Legend
Tampa → Seattle
from$1,070pp · cruise fare≈ $67/night pp
Fares checked nightly
AmericasCarnival Cruise Line
16 nights: Seattle & Cabo San Lucas, South America
Aboard Carnival Miracle
Seattle → Galveston
from$935pp · cruise fare≈ $58/night pp
Fares checked nightly
Panama CanalNorwegian Cruise Line
16 nights: Cabo San Lucas, the Panama Canal
Aboard Norwegian Joy
Los Angeles → Miami
from$1,589pp · cruise fare≈ $99/night pp
Fares checked nightly
Panama CanalNorwegian Cruise Line
16 nights: Puerto Vallarta & Cabo San Lucas, the Panama Canal
Aboard Norwegian Star
Miami → San Diego
from$1,489pp · cruise fare≈ $93/night pp
Fares checked nightly
AmericasOceania Cruises
16 nights: Ensenada & Cabo San Lucas, South America
Aboard Oceania Sonata
Los Angeles → Miami
Panama CanalSeabourn
19 nights in the Panama Canal
Aboard Seabourn Quest
19-Night World Cruise: Panama Canal Crossing
from$11,474pp · cruise fare≈ $604/night pp
Fares checked nightly
Panama CanalHX Expeditions
23 nights: Seattle, the Panama Canal
Aboard MS Fridtjof Nansen
New York → Seattle
Panama CanalHX Expeditions
23 nights: Seattle, the Panama Canal
Aboard MS Roald Amundsen
Seattle → New York
AmericasHolland America Line
21 nights: Vancouver & Puerto Vallarta, South America
Aboard Nieuw Amsterdam
Vancouver → Fort Lauderdale
from$1,164pp · cruise fare≈ $55/night pp
Fares checked nightly
AmericasHolland America Line
15 nights: Aruba & Cabo San Lucas, South America
Aboard Oosterdam
Fort Lauderdale → San Diego
from$2,779pp · cruise fare≈ $185/night pp
Fares checked nightly
AmericasHolland America Line
20 nights: Vancouver & Cabo San Lucas, South America
Aboard Eurodam
Vancouver → Fort Lauderdale
from$159pp · cruise fare≈ $8/night pp
Fares checked nightly
AmericasEmerald Cruises
11 nights in South America
Aboard Emerald Azzurra
Bridgetown → Panama City
AmericasOceania Cruises
10 nights: Cozumel, South America
Aboard Oceania Marina
Miami → Panama City
AmericasHolland America Line
15 nights: Cabo San Lucas & Puerto Vallarta, South America
Aboard Zaandam
San Diego → Fort Lauderdale
from$899pp · cruise fare≈ $60/night pp
Fares checked nightly
Panama CanalVirgin Voyages
17 nights: Cabo San Lucas, the Panama Canal
Aboard Brilliant Lady
Los Angeles → Miami
from$1,032pp · cruise fare≈ $61/night pp
Fares checked nightly
Panama CanalMSC Cruises
19 nights: Seattle & Cabo San Lucas, the Panama Canal
Aboard MSC Poesia
Seattle → Miami
from$423pp · cruise fare≈ $22/night pp
Fares checked nightly
Panama CanalNorwegian Cruise Line
16 nights: Cabo San Lucas, the Panama Canal
Aboard Norwegian Bliss
Los Angeles → New York
from$1,679pp · cruise fare≈ $105/night pp
Fares checked nightly
AmericasAzamara
10 nights in South America
Aboard Azamara Quest
Fuerte Amador → Valparaiso
from$4,599pp · cruise fare≈ $460/night pp
Fares checked nightly
AmericasRegent Seven Seas Cruises
14 nights in South America
Aboard Seven Seas Grandeur
Panama City → Miami
AmericasRegent Seven Seas Cruises
11 nights: Cozumel, South America
Aboard Seven Seas Prestige
Panama City → Miami
Panama CanalCrystal
25 nights in the Panama Canal
Aboard Crystal Serenity
San Diego to New York
Frequently asked
- How many Panama Canal cruises does NestCruise have?
- 98 live sailings, 11 to 23 nights. A NestCruise advisor narrows them to the one that fits.
- Which cruise lines run Panama Canal cruises?
- Regent Seven Seas Cruises, Holland America Line, Oceania Cruises and Norwegian Cruise Line, among others.
- How long are Panama Canal cruises?
- Most run 11 to 23 nights.
- How much do Panama Canal cruises cost?
- NestCruise doesn't publish fares — it's a quote-only concierge. Share your dates and party size and an advisor prices your exact sailing at no cost.