Cruise itinerary
10-Night Caribbean Cruise from Los Angeles, California
10 nights · Caribbean · 7 ports of call
10-night Caribbean cruise aboard Seven Seas Grandeur, departing Los Angeles, California and calling at Cruising the Pacific Ocean, Cabo San Lucas, La Paz, Mazatlán, Manzanillo, Mexico and Puerto Vallarta.
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- 10,000+ sailings
At a glance
- Cruise line
- Regent Seven Seas Cruises
- Duration
- 10 nights
- Region
- Caribbean · Americas · South America · Panama Canal
- Departs
- Los Angeles, California
- Returns
- Los Angeles, California
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Seven Seas Grandeur sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1
Los Angeles, California
Arrive 07:00 · Depart 17:00
The sprawling Pacific gateway of southern California, with most cruises sailing from the neighbouring Port of Los Angeles at San Pedro. The morning leaves time for Hollywood, the beaches at Santa Monica or the galleries downtown before departure.
- Hollywood
- Santa Monica Pier
- Getty Center
- Day2
Cruising the Pacific Ocean
- Day3
Cruising the Pacific Ocean
- Day4
Cabo San Lucas
Arrive 08:00 · Depart 19:00
A resort town at the southern tip of Mexico's Baja California peninsula, where the desert meets the Pacific and Sea of Cortez. Cabo San Lucas is known for its rock arch at Land's End, sport fishing, and the marina lined with restaurants and boats.
- El Arco
- Lover's Beach
- Cabo marina
- Day5
La Paz
Arrive 07:00 · Depart 15:30
- Day6
Mazatlán
Arrive 08:30 · Depart 15:30
A Pacific-coast resort city in Sinaloa, Mexico, strung along one of the longest seafront promenades in the country. The old town centres on the cathedral and Plaza Machado, while the Golden Zone draws beachgoers and the working harbour still lands shrimp.
- El Malecón
- Old Mazatlán
- Stone Island
- Day7
Manzanillo, Mexico
Arrive 11:00 · Depart 18:30
- Day8
Puerto Vallarta
Arrive 07:00 · Depart 15:00
A resort city on Mexico's Pacific coast, set where the Sierra Madre meets Banderas Bay. Its cobbled Zona Romántica and the seaside Malecón promenade anchor an old town of churches and galleries, with whale-watching in the bay through the winter months.
- The Malecón
- Zona Romántica
- Banderas Bay
- Day9
Cruising the Pacific Ocean
- Day10
Cruising the Pacific Ocean
- Day11
Los Angeles, California
Arrive 07:00 · Depart 17:00
The sprawling Pacific gateway of southern California, with most cruises sailing from the neighbouring Port of Los Angeles at San Pedro. The morning leaves time for Hollywood, the beaches at Santa Monica or the galleries downtown before departure.
- Hollywood
- Santa Monica Pier
- Getty Center
Upcoming departures
- 14 Jan 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
10-Night Caribbean Cruise from Los Angeles, California FAQ
Which ports does this cruise visit?
This 10-night Caribbean cruise calls at Los Angeles, California, Cruising the Pacific Ocean, Cabo San Lucas, La Paz, Mazatlán, Manzanillo, Mexico and Puerto Vallarta.
How many days are spent at sea?
4 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It is a round-trip sailing from Los Angeles, California.
How long is this cruise?
10 nights aboard Seven Seas Grandeur.
When does this itinerary sail?
Upcoming departures include 14 Jan 2027. A NestCruise advisor can confirm current availability.