Cruises to Santo Tomás de Castilla
37 live cruises call at Santo Tomás de Castilla — 9 to 41 nights, departing 10 ports, across 4 lines. A NestCruise advisor narrows them to the one that fits.
AmericasOceania Cruises
Panama Potpourri
Aboard Oceania Marina
Miami, Florida → At Sea → Cozumel → Costa Maya +6 more
10 nights · 2 departures
Port-rich · 10 ports
CaribbeanCrystal
Roundtrip Fort Lauderdale
Aboard Crystal Serenity
Fort Lauderdale, Florida → At Sea → Cozumel → Belize City +2 more
7 nights · 1 departure
Port-rich · 6 ports
CaribbeanRegent Seven Seas Cruises
Fall For The Caribbean
Aboard Seven Seas Grandeur
Miami, Florida → Cruising the Caribbean Sea → Roatán Island → Santo Tomás de Castilla +3 more
7 nights · 1 departure
Port-rich · 7 ports
CaribbeanRegent Seven Seas Cruises
Sea, Sun & Salsa
Aboard Seven Seas Prestige
Miami, Florida → Cruising the Caribbean Sea → Belize City → Harvest Caye +3 more
7 nights · 1 departure
Port-rich · 7 ports
CaribbeanExplora Journeys
A Journey into Tropical Idylls & Mayan Mystery
Aboard EXPLORA I
Miami, Florida → At Sea → Cozumel → Costa Maya +3 more
8 nights · 1 departure
Port-rich · 7 ports
CaribbeanExplora Journeys
A Journey through Sacred Cenotes & Hidden Mayan Pyramids
Aboard EXPLORA IV
Miami, Florida → At Sea → Cozumel → Costa Maya +4 more
9 nights · 1 departure
Port-rich · 8 ports
CaribbeanCrystal
Fort Lauderdale to Cartagena
Aboard Crystal Symphony
Fort Lauderdale, Florida → At Sea → Cozumel → Belize City +5 more
10 nights · 1 departure
Port-rich · 9 ports
CaribbeanRegent Seven Seas Cruises
Blue Seas & Pastel Towns
Aboard Seven Seas Splendor
Galveston, Texas → At Sea → Cozumel → Belize City +9 more
14 nights · 1 departure
Port-rich · 13 ports
AmericasOceania Cruises
Spanish Lullaby
Aboard Oceania Marina
Panama City → Panama Canal Transit → At Sea → Puerto Limón +5 more
10 nights · 1 departure
Port-rich · 9 ports
CaribbeanCrystal
Cartagena to Fort Lauderdale
Aboard Crystal Serenity
Cartagena → Colón → Puerto Limón → At Sea +5 more
10 nights · 1 departure
Port-rich · 9 ports
AmericasRegent Seven Seas Cruises
A Festive Passage
Aboard Seven Seas Grandeur
Miami, Florida → Key West, Florida → Cruising the Florida Straits → Cozumel +9 more
14 nights · 1 departure
Port-rich · 13 ports
CaribbeanRegent Seven Seas Cruises
Reggae Rhythms
Aboard Seven Seas Prestige
Miami, Florida → Cruising the Florida Straits → Cozumel → Santo Tomás de Castilla +5 more
10 nights · 1 departure
Port-rich · 9 ports
CaribbeanExplora Journeys
A Journey of Enchanting Ancient History & Coastal Splendour
Aboard EXPLORA I
Miami, Florida → At Sea → Ocho Rios → Santo Tomás de Castilla +3 more
9 nights · 1 departure
Balanced · 7 ports
CaribbeanCrystal
Round trip Fort Lauderdale
Aboard Crystal Symphony
Fort Lauderdale, Florida → At Sea → Cozumel → Belize City +5 more
11 nights · 1 departure
Port-rich · 9 ports
AmericasOceania Cruises
Treasures Of The Tropics
Aboard Oceania Marina
Miami, Florida → At Sea → Georgetown, Grand Cayman → Montego Bay +10 more
20 nights · 1 departure
Balanced · 14 ports
CaribbeanCrystal
Fuerte Amador (Panama City) to Fort Lauderdale
Aboard Crystal Serenity
Fuerte Amador → Panama Canal Transit → Puerto Limón → At Sea +6 more
11 nights · 1 departure
Port-rich · 10 ports
MediterraneanRegent Seven Seas Cruises
Atlantic Ocean Isles
Aboard Seven Seas Grandeur
Civitavecchia → Cruising the Mediterranean Sea → Palma de Mallorca → Cruising the Strait of Gibraltar +10 more
21 nights · 1 departure
Balanced · 14 ports
AmericasRegent Seven Seas Cruises
Crescent Beaches & Colorful Towns
Aboard Seven Seas Prestige
Panama City → Panama Canal Transit → Puerto Limón → Cruising the Caribbean Sea +8 more
11 nights · 1 departure
Port-rich · 12 ports
CaribbeanExplora Journeys
An Extended Journey of Cultural Treasures & Seaside Harmony
Aboard EXPLORA I
Miami, Florida → At Sea → Cozumel → Costa Maya +8 more
15 nights · 1 departure
Port-rich · 12 ports
CaribbeanCrystal
Roundtrip Fort Lauderdale
Aboard Crystal Symphony
Fort Lauderdale, Florida → At Sea → New Orleans, Louisiana → Cozumel +4 more
13 nights · 1 departure
Balanced · 8 ports
CaribbeanOceania Cruises
Panama Canal & Caribbean
Aboard Oceania Marina
Miami, Florida → At Sea → Cozumel → Costa Maya +12 more
20 nights · 1 departure
Port-rich · 16 ports
AmericasCrystal
Valparaiso to Fort Lauderdale
Aboard Crystal Serenity
Valparaiso → Coquimbo → At Sea → Iquique +13 more
23 nights · 1 departure
Balanced · 17 ports
CaribbeanRegent Seven Seas Cruises
Cupid In The Caribbean
Aboard Seven Seas Prestige
Miami, Florida → Key West, Florida → At Sea → Cozumel +7 more
11 nights · 1 departure
Port-rich · 11 ports
CaribbeanExplora Journeys
An Extended Journey through Ancient Marvels & Glittering Shores
Aboard EXPLORA I
Miami, Florida → At Sea → Ocho Rios → Santo Tomás de Castilla +8 more
16 nights · 1 departure
Balanced · 12 ports
CaribbeanCrystal
Fort Lauderdale to Callao (Lima)
Aboard Crystal Symphony
Fort Lauderdale, Florida → At Sea → Cozumel → Belize City +10 more
18 nights · 1 departure
Port-rich · 14 ports
CaribbeanCrystal
Roundtrip Fort Lauderdale
Aboard Crystal Serenity
Fort Lauderdale, Florida → At Sea → Road Town, Tortola → Gustavia +17 more
27 nights · 1 departure
Port-rich · 21 ports
CaribbeanRegent Seven Seas Cruises
Azure Elegance
Aboard Seven Seas Prestige
Miami, Florida → Cruising the Florida Straits → Progreso → Cruising the Caribbean Sea +5 more
11 nights · 1 departure
Port-rich · 9 ports
CaribbeanExplora Journeys
An Extended Journey of Historic Echoes & Ocean Breezes
Aboard EXPLORA I
Miami, Florida → At Sea → Willemstad → Oranjestad +8 more
18 nights · 1 departure
Balanced · 12 ports
CaribbeanCrystal
Roundtrip Fort Lauderdale
Aboard Crystal Symphony
Fort Lauderdale, Florida → At Sea → Saint Thomas → Virgin Gorda +10 more
21 nights · 1 departure
Balanced · 14 ports
AmericasCrystal
Buenos Aires to Fort Lauderdale
Aboard Crystal Serenity
Buenos Aires → Punta del Este → At Sea → Puerto Madryn +24 more
41 nights · 1 departure
Balanced · 28 ports
CaribbeanExplora Journeys
An Extended Journey of Coastal Marvels & Caribbean Dreams
Aboard EXPLORA I
Miami, Florida → At Sea → Puerto Plata → Cayo Levantado +8 more
18 nights · 1 departure
Balanced · 12 ports
CaribbeanCrystal
Roundtrip Fort Lauderdale
Aboard Crystal Symphony
Fort Lauderdale, Florida → At Sea → Cozumel → Belize City +17 more
27 nights · 1 departure
Port-rich · 21 ports
AmericasCrystal
New York City to Fort Lauderdale
Aboard Crystal Serenity
New York, New York → At Sea → Kings Wharf → Saint John's +41 more
71 nights · 1 departure
Balanced · 45 ports
CaribbeanCrystal
Fort Lauderdale to Papeete, Tahiti
Aboard Crystal Symphony
Fort Lauderdale, Florida → At Sea → Cozumel → Belize City +16 more
33 nights · 1 departure
Balanced · 20 ports
AsiaCrystal
Fort Lauderdale to Singapore
Aboard Crystal Symphony
Fort Lauderdale, Florida → At Sea → Cozumel → Belize City +46 more
85 nights · 1 departure
Balanced · 50 ports
Frequently asked
- How many cruises to Santo Tomás de Castilla does NestCruise have?
- 37 live sailings, 9 to 41 nights. A NestCruise advisor narrows them to the one that fits.
- Which cruise lines visit Santo Tomás de Castilla?
- Crystal, Regent Seven Seas Cruises, Explora Journeys and Oceania Cruises, among others.
- How long are cruises to Santo Tomás de Castilla?
- Most run 9 to 41 nights.
- How much do cruises to Santo Tomás de Castilla cost?
- NestCruise doesn't publish fares — it's a quote-only concierge. Share your dates and party size and an advisor prices your exact sailing at no cost.