Cruise itinerary
41-Night Americas Cruise from Buenos Aires
41 nights · Americas · 28 ports of call
41-night Americas cruise aboard Crystal Serenity, departing Buenos Aires and calling at Punta del Este, At Sea, Puerto Madryn, Port Stanley, Ushuaia and Punta Arenas and 21 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Crystal Serenity
- Cruise line
- Crystal
- Duration
- 41 nights
- Region
- Americas · South America
- Departs
- Buenos Aires
- Returns
- Fort Lauderdale, Florida
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Crystal Serenity sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1
Buenos Aires
Argentina's grand capital on the Río de la Plata, a city of wide boulevards and European-style architecture. The tango was born in its streets, with the colourful houses of La Boca and the cafés of San Telmo close to the waterfront.
- La Boca
- San Telmo
- Tango culture
- Day2
Punta del Este
- Day3
At Sea
- Day4
Puerto Madryn
A Patagonian port on the Gulf of Nuevo in Argentine coastal Chubut, founded by Welsh settlers. It is the gateway to the Península Valdés nature reserve, where southern right whales, sea lions and penguins gather along the coast.
- Península Valdés
- Whale watching
- Welsh heritage
- Day5
At Sea
- Day6
Port Stanley
The small capital of the Falkland Islands in the South Atlantic, a row of brightly painted houses and tin roofs along a sheltered harbour. Penguin colonies and windswept moorland surround the settlement, with Christ Church Cathedral and its whalebone arch at the waterfront.
- Penguin colonies
- Whalebone Arch
- Christ Church Cathedral
- Day7
At Sea
- Day8
Ushuaia
The world's southernmost city, on Argentina's Tierra del Fuego at the tip of South America. Backed by snowy peaks on the Beagle Channel, it is the chief departure port for Antarctica and a base for the Patagonian wilderness.
- Beagle Channel
- Tierra del Fuego park
- End of the world
- Day9
Punta Arenas
A windswept city on the Strait of Magellan in Chilean Patagonia, one of the southernmost ports on earth. It serves as a gateway to Tierra del Fuego, Antarctic crossings and nearby penguin colonies, with a grand central plaza recalling the wool and shipping boom.
- Strait of Magellan
- Plaza de Armas
- Penguin colonies
- Day10
Punta Arenas
A windswept city on the Strait of Magellan in Chilean Patagonia, one of the southernmost ports on earth. It serves as a gateway to Tierra del Fuego, Antarctic crossings and nearby penguin colonies, with a grand central plaza recalling the wool and shipping boom.
- Strait of Magellan
- Plaza de Armas
- Penguin colonies
- Day11
Chilean Fjords
- Day12
Chilean Fjords
- Day13
Laguna San Rafael National Park
- Day14
Puerto Chacabuco
- Day15
Castro
- Day16
Puerto Montt
A port city in Chile's Lake District, set on the Reloncaví Sound where the central valley meets the fjords of Patagonia. Snow-capped volcanoes ring the bay, and the town is a launch point for trips to lakes, the German-influenced settlement of Puerto Varas and Chiloé island.
- Osorno Volcano
- Puerto Varas
- Angelmó market
- Day17
At Sea
- Day18
Valparaiso
A historic port city on Chile's central coast, built across steep hills laced with funiculars and painted houses. A UNESCO World Heritage site, it serves as the gateway to Santiago and the Casablanca wine valley, with a busy working harbour below.
- Hillside funiculars
- Cerro Concepción
- Casablanca wineries
- Day19
Valparaiso
A historic port city on Chile's central coast, built across steep hills laced with funiculars and painted houses. A UNESCO World Heritage site, it serves as the gateway to Santiago and the Casablanca wine valley, with a busy working harbour below.
- Hillside funiculars
- Cerro Concepción
- Casablanca wineries
- Day20
Coquimbo
- Day21
At Sea
- Day22
Iquique
- Day23
At Sea
- Day24
Pisco
- Day25
Callao
Peru's chief seaport, on the Pacific beside Lima. Ships dock here for the colonial centre and museums of the capital, the cliff-top Miraflores district above the ocean, and onward journeys toward Machu Picchu and the Andean highlands.
- Gateway to Lima
- Miraflores
- Historic centre
- Day26
Salaverry
- Day27
At Sea
- Day28
Guayaquil
- Day29
At Sea
- Day30
Fuerte Amador
A causeway-linked island port on the Pacific side of the Panama Canal, just off Panama City. It serves as the gateway to the canal's locks and rainforest, with the Amador Causeway reaching toward the capital's skyline and old quarter.
- Panama Canal
- Amador Causeway
- Casco Viejo
- Day31
Fuerte Amador
A causeway-linked island port on the Pacific side of the Panama Canal, just off Panama City. It serves as the gateway to the canal's locks and rainforest, with the Amador Causeway reaching toward the capital's skyline and old quarter.
- Panama Canal
- Amador Causeway
- Casco Viejo
- Day32
Panama Canal Transit
Fuerte Amador
A causeway-linked island port on the Pacific side of the Panama Canal, just off Panama City. It serves as the gateway to the canal's locks and rainforest, with the Amador Causeway reaching toward the capital's skyline and old quarter.
- Panama Canal
- Amador Causeway
- Casco Viejo
- Day33
Puerto Limón
A Caribbean port on Costa Rica's humid eastern coast, the country's main Atlantic harbour. It opens onto rainforest, banana plantations and the canals of Tortuguero, with white-faced monkeys and sloths a frequent sight on excursions inland.
- Tortuguero canals
- Rainforest wildlife
- Banana country
- Day34
At Sea
- Day35
Roatán Island
An island off the northern coast of Honduras in the western Caribbean, part of the Bay Islands. Roatán is known for the Mesoamerican Barrier Reef just offshore, the dive sites and beaches around West End and West Bay, and forested inland hills.
- West Bay Beach
- Barrier reef diving
- West End
- Day36
Santo Tomás de Castilla
- Day37
Belize City
The largest city in Belize, on the Caribbean coast where the Belize River meets the sea. A tender port for many ships, it opens the way to the world's second-largest barrier reef, jungle Maya ruins and cave-tubing excursions inland.
- Barrier reef
- Maya ruins
- Cave tubing
- Day38
Cozumel
An island off Mexico's Yucatán coast in the Caribbean, a leading port for snorkelling and diving. Ships dock beside its reefs, part of the Mesoamerican system, with beach clubs, Mayan ruins and the resort strip of the Riviera Maya within reach.
- Coral reefs
- Mayan ruins
- Beach clubs
- Day39
Cozumel
An island off Mexico's Yucatán coast in the Caribbean, a leading port for snorkelling and diving. Ships dock beside its reefs, part of the Mesoamerican system, with beach clubs, Mayan ruins and the resort strip of the Riviera Maya within reach.
- Coral reefs
- Mayan ruins
- Beach clubs
- Day40
Progreso
- Day41
At Sea
- Day42
Fort Lauderdale, Florida
A South Florida port often called the yachting capital, fringed by canals and the long sands of Fort Lauderdale Beach. Port Everglades is among the world's busiest cruise gateways, with Las Olas Boulevard's shops and cafés minutes from the piers.
- Port Everglades
- Las Olas Boulevard
- Fort Lauderdale Beach
Upcoming departures
- 11 Nov 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
41-Night Americas Cruise from Buenos Aires FAQ
Which ports does this cruise visit?
This 41-night Americas cruise calls at Buenos Aires, Punta del Este, At Sea, Puerto Madryn, Port Stanley, Ushuaia, Punta Arenas, Chilean Fjords, Laguna San Rafael National Park, Puerto Chacabuco, Castro, Puerto Montt, Valparaiso, Coquimbo, Iquique, Pisco, Callao, Salaverry, Guayaquil, Fuerte Amador, Panama Canal Transit, Puerto Limón, Roatán Island, Santo Tomás de Castilla, Belize City, Cozumel, Progreso and Fort Lauderdale, Florida.
How many days are spent at sea?
10 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Buenos Aires and ends in Fort Lauderdale, Florida.
How long is this cruise?
41 nights aboard Crystal Serenity.
When does this itinerary sail?
Upcoming departures include 11 Nov 2027. A NestCruise advisor can confirm current availability.