Cruise itinerary
21-Night Mediterranean Cruise from Civitavecchia
21 nights · Mediterranean · 14 ports of call
21-night Mediterranean cruise aboard Seven Seas Grandeur, departing Civitavecchia and calling at Cruising the Mediterranean Sea, Palma de Mallorca, Cruising the Strait of Gibraltar, Sailing the Atlantic Ocean, Funchal, Madeira and Kings Wharf and 7 more.
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At a glance
- Cruise line
- Regent Seven Seas Cruises
- Duration
- 21 nights
- Region
- Mediterranean · Transatlantic
- Departs
- Civitavecchia
- Returns
- Miami, Florida
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Seven Seas Grandeur sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1
Civitavecchia
Arrive 06:00 · Depart 17:00
The deep-water port serving Rome, roughly 80 kilometres up the coast. Ships dock here for shore excursions to the Colosseum, the Vatican and the Roman Forum, while the town itself keeps a working harbour and a Michelangelo-designed fortress.
- Gateway to Rome
- Fort Michelangelo
- Vatican excursions
- Day2
Cruising the Mediterranean Sea
- Day3
Palma de Mallorca
Arrive 08:00 · Depart 16:00
The capital of Mallorca in Spain's Balearic Islands, set around a wide bay. Its enormous seafront cathedral, La Seu, rises above the old town's narrow lanes, with a hilltop castle, marina and nearby coves a short way from the cruise terminal.
- La Seu cathedral
- Bellver Castle
- Old town
- Day4
Cruising the Strait of Gibraltar
- Day5
Sailing the Atlantic Ocean
- Day6
Funchal, Madeira
Arrive 09:00 · Depart 16:00
The capital of Madeira, a Portuguese island in the Atlantic, built up an amphitheatre of green hills above its harbour. A cable car rises to Monte, where wicker toboggans slide back down, and the island is known for its fortified wine and mountain levada walks.
- Monte cable car
- Toboggan ride
- Madeira wine
- Day7
Sailing the Atlantic Ocean
- Day8
Sailing the Atlantic Ocean
- Day9
Sailing the Atlantic Ocean
- Day10
Sailing the Atlantic Ocean
- Day11
Sailing the Atlantic Ocean
- Day12
Kings Wharf
Arrive 09:00 · Depart 15:00
The cruise port at the western tip of Bermuda, set within the historic Royal Naval Dockyard. Kings Wharf is known for the old fortress turned shopping arcade, the National Museum of Bermuda, and ferries across the sound to Hamilton and the pink beaches.
- Royal Naval Dockyard
- National Museum
- Horseshoe Bay
- Day13
Sailing the Atlantic Ocean
- Day14
Sailing the Atlantic Ocean
- Day15
Miami, Florida
Arrive 07:00 · Depart 17:00
The cruise capital of the world — Miami sends more ships to sea than any port on earth. Most sailings board mid-afternoon, leaving the morning for South Beach, Little Havana or the Wynwood murals before you cast off.
- South Beach
- Little Havana
- Wynwood murals
- Day16
Cruising the Caribbean Sea
- Day17
Roatán Island
Arrive 13:00 · Depart 20:00
An island off the northern coast of Honduras in the western Caribbean, part of the Bay Islands. Roatán is known for the Mesoamerican Barrier Reef just offshore, the dive sites and beaches around West End and West Bay, and forested inland hills.
- West Bay Beach
- Barrier reef diving
- West End
- Day18
Santo Tomás de Castilla
Arrive 08:00 · Depart 18:00
- Day19
Harvest Caye
Arrive 08:00 · Depart 16:30
- Day20
Costa Maya
Arrive 08:00 · Depart 17:00
A purpose-built cruise port on Mexico's Caribbean coast in Quintana Roo, on the southern Costa Maya. It serves as a gateway to Mayan ruins at Chacchoben and Kohunlich, plus nearby reef snorkelling and the laid-back fishing village of Mahahual.
- Chacchoben ruins
- Mahahual village
- Reef snorkelling
- Day21
Cruising the Florida Straits
- Day22
Miami, Florida
Arrive 07:00 · Depart 17:00
The cruise capital of the world — Miami sends more ships to sea than any port on earth. Most sailings board mid-afternoon, leaving the morning for South Beach, Little Havana or the Wynwood murals before you cast off.
- South Beach
- Little Havana
- Wynwood murals
Upcoming departures
- 8 Nov 2026
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
21-Night Mediterranean Cruise from Civitavecchia FAQ
Which ports does this cruise visit?
This 21-night Mediterranean cruise calls at Civitavecchia, Cruising the Mediterranean Sea, Palma de Mallorca, Cruising the Strait of Gibraltar, Sailing the Atlantic Ocean, Funchal, Madeira, Kings Wharf, Miami, Florida, Cruising the Caribbean Sea, Roatán Island, Santo Tomás de Castilla, Harvest Caye, Costa Maya and Cruising the Florida Straits.
How many days are spent at sea?
4 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Civitavecchia and ends in Miami, Florida.
How long is this cruise?
21 nights aboard Seven Seas Grandeur.
When does this itinerary sail?
Upcoming departures include 8 Nov 2026. A NestCruise advisor can confirm current availability.