

Cruise itinerary
10-Night Caribbean Cruise from Miami, Florida
10 nights · Caribbean · 9 ports of call
10-night Caribbean cruise aboard Seven Seas Prestige, departing Miami, Florida and calling at Cruising the Florida Straits, Cozumel, Santo Tomás de Castilla, Harvest Caye, Roatán Island and Cruising the Caribbean Sea and 2 more.
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- No booking fees
- 10,000+ sailings
At a glance
- Cruise line
- Regent Seven Seas Cruises
- Duration
- 10 nights
- Region
- Caribbean · Americas
- Departs
- Miami, Florida
- Returns
- Miami, Florida
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Seven Seas Prestige sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Miami, Florida
Arrive 07:00 · Depart 16:00
The cruise capital of the world — Miami sends more ships to sea than any port on earth. Most sailings board mid-afternoon, leaving the morning for South Beach, Little Havana or the Wynwood murals before you cast off.
- South Beach
- Little Havana
- Wynwood murals
- Day2
Cruising the Florida Straits
- Day3

Cozumel
Arrive 07:00 · Depart 16:00
An island off Mexico's Yucatán coast in the Caribbean, a leading port for snorkelling and diving. Ships dock beside its reefs, part of the Mesoamerican system, with beach clubs, Mayan ruins and the resort strip of the Riviera Maya within reach.
- Coral reefs
- Mayan ruins
- Beach clubs
- Day4

Santo Tomás de Castilla
Arrive 11:00 · Depart 18:00
- Day5

Harvest Caye
Arrive 08:00 · Depart 17:00
- Day6

Roatán Island
Arrive 08:00 · Depart 17:00
An island off the northern coast of Honduras in the western Caribbean, part of the Bay Islands. Roatán is known for the Mesoamerican Barrier Reef just offshore, the dive sites and beaches around West End and West Bay, and forested inland hills.
- West Bay Beach
- Barrier reef diving
- West End
- Day7
Cruising the Caribbean Sea
- Day8

Falmouth
Arrive 07:00 · Depart 16:00
A restored Georgian port town on Jamaica's north coast, purpose-built for large cruise ships. Streets of 18th-century merchant houses sit just beyond the pier, with Montego Bay's beaches and the Martha Brae's bamboo-raft river a short drive west.
- Georgian streets
- Martha Brae rafting
- Montego Bay
- Day9

Georgetown, Grand Cayman
Arrive 08:00 · Depart 16:00
Grand Cayman's capital and the main port of the Cayman Islands, set on the calm western shore. Cruise ships tender into the harbour beside Seven Mile Beach, with Stingray City sandbars and Caribbean reef diving a short boat ride away.
- Seven Mile Beach
- Stingray City
- Seven Mile reefs
- Day10
Cruising the Florida Straits
- Day11

Miami, Florida
Arrive 07:00 · Depart 16:00
The cruise capital of the world — Miami sends more ships to sea than any port on earth. Most sailings board mid-afternoon, leaving the morning for South Beach, Little Havana or the Wynwood murals before you cast off.
- South Beach
- Little Havana
- Wynwood murals
Upcoming departures
- 27 Nov 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
10-Night Caribbean Cruise from Miami, Florida FAQ
Which ports does this cruise visit?
This 10-night Caribbean cruise calls at Miami, Florida, Cruising the Florida Straits, Cozumel, Santo Tomás de Castilla, Harvest Caye, Roatán Island, Cruising the Caribbean Sea, Falmouth and Georgetown, Grand Cayman.
How many days are spent at sea?
3 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It is a round-trip sailing from Miami, Florida.
How long is this cruise?
10 nights aboard Seven Seas Prestige.
When does this itinerary sail?
Upcoming departures include 27 Nov 2027. A NestCruise advisor can confirm current availability.