

Cruise itinerary
23-Night Americas Cruise from Valparaiso
23 nights · Americas · 17 ports of call
23-night Americas cruise aboard Crystal Serenity, departing Valparaiso and calling at Coquimbo, At Sea, Iquique, Pisco, Callao and Salaverry and 10 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Crystal Serenity
- Cruise line
- Crystal
- Duration
- 23 nights
- Region
- Americas · South America
- Departs
- Valparaiso
- Returns
- Fort Lauderdale, Florida
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Crystal Serenity sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Valparaiso
A historic port city on Chile's central coast, built across steep hills laced with funiculars and painted houses. A UNESCO World Heritage site, it serves as the gateway to Santiago and the Casablanca wine valley, with a busy working harbour below.
- Hillside funiculars
- Cerro Concepción
- Casablanca wineries
- Day2

Coquimbo
- Day3
At Sea
- Day4

Iquique
- Day5
At Sea
- Day6

Pisco
- Day7

Callao
Peru's chief seaport, on the Pacific beside Lima. Ships dock here for the colonial centre and museums of the capital, the cliff-top Miraflores district above the ocean, and onward journeys toward Machu Picchu and the Andean highlands.
- Gateway to Lima
- Miraflores
- Historic centre
- Day8

Salaverry
- Day9
At Sea
- Day10

Guayaquil
- Day11
At Sea
- Day12

Fuerte Amador
A causeway-linked island port on the Pacific side of the Panama Canal, just off Panama City. It serves as the gateway to the canal's locks and rainforest, with the Amador Causeway reaching toward the capital's skyline and old quarter.
- Panama Canal
- Amador Causeway
- Casco Viejo
- Day13

Fuerte Amador
A causeway-linked island port on the Pacific side of the Panama Canal, just off Panama City. It serves as the gateway to the canal's locks and rainforest, with the Amador Causeway reaching toward the capital's skyline and old quarter.
- Panama Canal
- Amador Causeway
- Casco Viejo
- Day14
Panama Canal Transit

Fuerte Amador
A causeway-linked island port on the Pacific side of the Panama Canal, just off Panama City. It serves as the gateway to the canal's locks and rainforest, with the Amador Causeway reaching toward the capital's skyline and old quarter.
- Panama Canal
- Amador Causeway
- Casco Viejo
- Day15

Puerto Limón
A Caribbean port on Costa Rica's humid eastern coast, the country's main Atlantic harbour. It opens onto rainforest, banana plantations and the canals of Tortuguero, with white-faced monkeys and sloths a frequent sight on excursions inland.
- Tortuguero canals
- Rainforest wildlife
- Banana country
- Day16
At Sea
- Day17

Roatán Island
An island off the northern coast of Honduras in the western Caribbean, part of the Bay Islands. Roatán is known for the Mesoamerican Barrier Reef just offshore, the dive sites and beaches around West End and West Bay, and forested inland hills.
- West Bay Beach
- Barrier reef diving
- West End
- Day18

Santo Tomás de Castilla
- Day19

Belize City
The largest city in Belize, on the Caribbean coast where the Belize River meets the sea. A tender port for many ships, it opens the way to the world's second-largest barrier reef, jungle Maya ruins and cave-tubing excursions inland.
- Barrier reef
- Maya ruins
- Cave tubing
- Day20

Cozumel
An island off Mexico's Yucatán coast in the Caribbean, a leading port for snorkelling and diving. Ships dock beside its reefs, part of the Mesoamerican system, with beach clubs, Mayan ruins and the resort strip of the Riviera Maya within reach.
- Coral reefs
- Mayan ruins
- Beach clubs
- Day21

Cozumel
An island off Mexico's Yucatán coast in the Caribbean, a leading port for snorkelling and diving. Ships dock beside its reefs, part of the Mesoamerican system, with beach clubs, Mayan ruins and the resort strip of the Riviera Maya within reach.
- Coral reefs
- Mayan ruins
- Beach clubs
- Day22

Progreso
- Day23
At Sea
- Day24

Fort Lauderdale, Florida
A South Florida port often called the yachting capital, fringed by canals and the long sands of Fort Lauderdale Beach. Port Everglades is among the world's busiest cruise gateways, with Las Olas Boulevard's shops and cafés minutes from the piers.
- Port Everglades
- Las Olas Boulevard
- Fort Lauderdale Beach
Upcoming departures
- 29 Nov 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
23-Night Americas Cruise from Valparaiso FAQ
Which ports does this cruise visit?
This 23-night Americas cruise calls at Valparaiso, Coquimbo, At Sea, Iquique, Pisco, Callao, Salaverry, Guayaquil, Fuerte Amador, Panama Canal Transit, Puerto Limón, Roatán Island, Santo Tomás de Castilla, Belize City, Cozumel, Progreso and Fort Lauderdale, Florida.
How many days are spent at sea?
6 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Valparaiso and ends in Fort Lauderdale, Florida.
How long is this cruise?
23 nights aboard Crystal Serenity.
When does this itinerary sail?
Upcoming departures include 29 Nov 2027. A NestCruise advisor can confirm current availability.