Cruises to San Diego
169 live cruises call at San Diego — 4 to 35 nights, departing 17 ports, across 13 lines. A NestCruise advisor narrows them to the one that fits.
AmericasDisney Cruise Line
3-Night Baja Cruise from San Diego
Aboard Disney Wonder
San Diego, California → Ensenada → At Sea
3 nights · 6 departures
Balanced · 3 ports
AmericasRoyal Caribbean International
3 Night Ensenada Cruise
Aboard Serenade of the Seas
San Diego, California → Ensenada
3 nights · 6 departures
Sea-paced · 2 ports
AmericasNorwegian Cruise Line
Mexican Riviera: Cabo San Lucas & Puerto Vallarta
Aboard Norwegian Star
San Diego, California → Cabo San Lucas → Mazatlán → Puerto Vallarta
7 nights · 6 departures
Sea-paced · 4 ports
PacificHolland America Line
17-Day Circle Hawaii
Aboard Koningsdam
Vancouver, British Columbia → Hilo, Hawaii → Kahului-Maui, Hawaii → Lihue, Kauai Island, Hawaii +4 more
17 nights · 6 departures
Sea-paced · 8 ports
West Coast USPrincess Cruises
7-Night West Coast US Cruise
Aboard Emerald Princess
Los Angeles → Santa Barbara CA → Ensenada → San Diego +1 more
7 nights · 5 departures
Balanced · 5 ports
AmericasDisney Cruise Line
3-Night Halloween on the High Seas Baja Cruise from San Diego
Aboard Disney Magic
San Diego, California → Ensenada → At Sea
3 nights · 4 departures
Balanced · 3 ports
AmericasHolland America Line
7-Day Mexican Riviera
Aboard Zaandam
San Diego, California → Cabo San Lucas → La Paz → Loreto
7 nights · 3 departures
Sea-paced · 4 ports
AmericasHolland America Line
16-Day Panama Canal
Aboard Eurodam
San Diego, California → Cabo San Lucas → Acapulco → Huatulco (Santa María Huatulco) +5 more
16 nights · 3 departures
Balanced · 9 ports
West Coast USPrincess Cruises
7-Night West Coast US Cruise
Aboard Crown Princess
Los Angeles → San Francisco → Santa Barbara CA → San Diego +1 more
7 nights · 2 departures
Balanced · 5 ports
West Coast USPrincess Cruises
7-Night West Coast US Cruise
Aboard Ruby Princess
San Francisco → Santa Catalina Island CA → Los Angeles → San Diego +1 more
7 nights · 2 departures
Balanced · 5 ports
AmericasVirgin Voyages
Pacific Coastal: Vancouver to LA
Aboard Brilliant Lady
Vancouver, British Columbia → At Sea → San Francisco, California → Santa Barbara, California +3 more
8 nights · 2 departures
Port-rich · 7 ports
AmericasCrystal
Roundtrip San Diego
Aboard Crystal Serenity
San Diego, California → At Sea → Topolobampo → Loreto +2 more
9 nights · 2 departures
Balanced · 6 ports
AmericasHolland America Line
21-Day Panama Canal
Aboard Nieuw Amsterdam
Vancouver, British Columbia → San Francisco, California → San Diego, California → Puerto Vallarta +7 more
21 nights · 2 departures
Balanced · 11 ports
West Coast USPrincess Cruises
4-Night West Coast US Cruise
Aboard Discovery Princess
Los Angeles → San Diego → Ensenada
4 nights · 1 departure
Balanced · 3 ports
PacificHolland America Line
6-Day Pacific Coastal Cruise
Aboard Oosterdam
San Diego, California → Seattle, Washington → Victoria, British Columbia → Vancouver, British Columbia
6 nights · 1 departure
Balanced · 4 ports
AmericasAzamara
Pacific Coast Cruise: Vancouver, Seattle & San Francisco
Aboard Azamara Quest
Vancouver Island, British Columbia → Seattle, Washington → Victoria, British Columbia → Astoria, Oregon +2 more
7 nights · 1 departure
Port-rich · 6 ports
AmericasCrystal
Vancouver to San Diego
Aboard Crystal Symphony
Vancouver, British Columbia → Victoria, British Columbia → Astoria, Oregon → At Sea +3 more
7 nights · 1 departure
Port-rich · 7 ports
AmericasExplora Journeys
A Journey from Californian Treasures to Dramatic British Columbian Shores
Aboard EXPLORA III
Los Angeles, California → San Diego, California → At Sea → San Francisco, California +2 more
7 nights · 1 departure
Port-rich · 6 ports
AmericasHolland America Line
7-Day Baja Peninsula
Aboard Zuiderdam
San Diego, California → Cabo San Lucas → La Paz → Loreto
7 nights · 1 departure
Sea-paced · 4 ports
HawaiiPrincess Cruises
12-Night Hawaii Cruise
Aboard Royal Princess
Honolulu → Los Angeles → San Diego → San Francisco +2 more
12 nights · 1 departure
Sea-paced · 6 ports
World CruiseMSC Cruises
San Diego, Cabo San Lucas, Puntarenas, BLB-Panam Canal, CTB-Panama Canal, Colon, Cartagena, Miami
Aboard MSC Poesia
San Diego, California → Cabo San Lucas → Puntarenas → Cruising Panama Canal +3 more
14 nights · 1 departure
Sea-paced · 7 ports
AmericasOceania Cruises
Treasures Of Two Oceans
Aboard Oceania Vista
Miami, Florida → At Sea → Georgetown, Grand Cayman → Cartagena +6 more
15 nights · 1 departure
Balanced · 10 ports
AmericasRegent Seven Seas Cruises
Panama Canal & Pacific Gems
Aboard Seven Seas Grandeur
Miami, Florida → Cruising the Florida Straits → Georgetown, Grand Cayman → Cruising the Caribbean Sea +9 more
16 nights · 1 departure
Port-rich · 13 ports
CaribbeanSilversea
Miami to Los Angeles
Aboard Silver Dawn
Miami, Florida → At Sea → Cartagena → Panama Canal Transit +5 more
18 nights · 1 departure
Sea-paced · 9 ports
PacificSilversea
San Diego to Papeete
Aboard Silver Whisper
San Diego, California → At Sea → Honolulu, Hawaii → Kailua-Kona, Hawaii +4 more
18 nights · 1 departure
Sea-paced · 8 ports
OceaniaPrincess Cruises
57-Night Oceania Cruise
Aboard Grand Princess
Sydney → Norfolk Island → Auckland → Tauranga +22 more
57 nights · 1 departure
Sea-paced · 26 ports
AmericasDisney Cruise Line
4-Night Baja Cruise from San Diego
Aboard Disney Wonder
San Diego, California → At Sea → Santa Catalina Island, California → Ensenada
4 nights · 6 departures
Port-rich · 4 ports
AmericasRoyal Caribbean International
4 Night Catalina & Ensenada Cruise
Aboard Serenade of the Seas
San Diego, California → Santa Catalina Island, California → Ensenada
4 nights · 6 departures
Balanced · 3 ports
AmericasNorwegian Cruise Line
Mexican Riviera: Cabo & Puerto Vallarta
Aboard Norwegian Star
San Diego, California → Puerto Vallarta → Cabo San Lucas
6 nights · 1 departure
Sea-paced · 3 ports
AmericasHolland America Line
7-Day Baja Peninsula
Aboard Koningsdam
San Diego, California → Cabo San Lucas → La Paz → Loreto
7 nights · 5 departures
Sea-paced · 4 ports
West Coast USPrincess Cruises
4-Night West Coast US Cruise
Aboard Emerald Princess
Los Angeles → San Diego → Ensenada
4 nights · 2 departures
Balanced · 3 ports
AmericasDisney Cruise Line
4-Night Halloween on the High Seas Baja Cruise from San Diego
Aboard Disney Magic
San Diego, California → Santa Catalina Island, California → Ensenada → At Sea
4 nights · 3 departures
Port-rich · 4 ports
PacificHolland America Line
4-Day Pacific Coastal Cruise
Aboard Zaandam
Vancouver, British Columbia → San Diego, California
4 nights · 2 departures
Sea-paced · 2 ports
AmericasHolland America Line
20-Day Panama Canal
Aboard Eurodam
Vancouver, British Columbia → Santa Barbara, California → San Diego, California → Cabo San Lucas +7 more
20 nights · 3 departures
Balanced · 11 ports
West Coast USPrincess Cruises
5-Night West Coast US Cruise
Aboard Crown Princess
Los Angeles → Santa Barbara CA → San Diego → Ensenada
5 nights · 1 departure
Balanced · 4 ports
West Coast USPrincess Cruises
5-Night West Coast US Cruise
Aboard Ruby Princess
San Francisco → San Diego → Ensenada
5 nights · 1 departure
Sea-paced · 3 ports
AmericasVirgin Voyages
Baja Mexico Halloween Cruise
Aboard Brilliant Lady
Los Angeles, California → Santa Catalina Island, California → San Diego, California → Ensenada +1 more
5 nights · 1 departure
Port-rich · 5 ports
AmericasCrystal
Vancouver to San Diego
Aboard Crystal Serenity
Vancouver, British Columbia → Victoria, British Columbia → Astoria, Oregon → At Sea +3 more
7 nights · 1 departure
Port-rich · 7 ports
PacificHolland America Line
4-Day Pacific Coastal Cruise
Aboard Nieuw Amsterdam
San Diego, California → Victoria, British Columbia → Vancouver, British Columbia
4 nights · 1 departure
Balanced · 3 ports
AmericasHolland America Line
15-Day Panama Canal
Aboard Oosterdam
Fort Lauderdale, Florida → Aruba → Puntarenas → Puerto Quetzal +3 more
15 nights · 1 departure
Sea-paced · 7 ports
AmericasAzamara
Panama Canal & Latin America Cruise: Mexico, Costa Rica & Colombia
Aboard Azamara Quest
San Diego, California → Cabo San Lucas → Acapulco → Puerto Quetzal +5 more
17 nights · 1 departure
Balanced · 9 ports
CaribbeanCrystal
San Diego to Vancouver
Aboard Crystal Symphony
San Diego, California → Santa Catalina Island, California → San Francisco, California → At Sea +4 more
8 nights · 1 departure
Port-rich · 8 ports
PacificExplora Journeys
An Extended Journey of Ancient Mysteries & Pacific Coastal Wonders
Aboard EXPLORA III
Panama City → At Sea → Acajutla → Puerto Quetzal +8 more
18 nights · 1 departure
Balanced · 12 ports
AmericasHolland America Line
7-Day Mexican Riviera
Aboard Zuiderdam
San Diego, California → La Paz → Mazatlán → Cabo San Lucas
7 nights · 1 departure
Sea-paced · 4 ports
HawaiiPrincess Cruises
13-Night Hawaii Cruise
Aboard Royal Princess
Honolulu → Kailua-Kona → San Diego → Los Angeles +3 more
13 nights · 1 departure
Balanced · 7 ports
World CruiseMSC Cruises
Los Angeles, San Diego, Cabo San Lucas, Puntarenas, BLB-Panam Canal, CTB-Panama Canal, Colon, Cartagena, Miami
Aboard MSC Poesia
Los Angeles, California → San Diego, California → Cabo San Lucas → Puntarenas +4 more
15 nights · 1 departure
Balanced · 8 ports
Frequently asked
- How many cruises to San Diego does NestCruise have?
- 169 live sailings, 4 to 35 nights. A NestCruise advisor narrows them to the one that fits.
- Which cruise lines visit San Diego?
- Holland America Line, Disney Cruise Line, Crystal and Princess Cruises, among others.
- How long are cruises to San Diego?
- Most run 4 to 35 nights.
- How much do cruises to San Diego cost?
- NestCruise doesn't publish fares — it's a quote-only concierge. Share your dates and party size and an advisor prices your exact sailing at no cost.