Cruise itinerary
12-Night Americas Cruise from San Diego, California
12 nights · Americas · 9 ports of call
12-night Americas cruise aboard Zaandam, departing San Diego, California and calling at Cabo San Lucas, Loreto, Guaymas, Topolobampo, La Paz and Mazatlán and 2 more.
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- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Zaandam
- Cruise line
- Holland America Line
- Duration
- 12 nights
- Region
- Americas · South America · Mexican Riviera
- Departs
- San Diego, California
- Returns
- San Diego, California
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Zaandam sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1
San Diego, California
Depart 15:00
A relaxed harbour city in southern California, known for its mild climate and broad natural bay. The waterfront holds the historic Gaslamp Quarter and maritime museums, with the green expanse of Balboa Park and its zoo just inland.
- Balboa Park
- Gaslamp Quarter
- San Diego Zoo
- Day2At sea
- Day3
Cabo San Lucas
Arrive 11:00 · Depart 18:00
A resort town at the southern tip of Mexico's Baja California peninsula, where the desert meets the Pacific and Sea of Cortez. Cabo San Lucas is known for its rock arch at Land's End, sport fishing, and the marina lined with restaurants and boats.
- El Arco
- Lover's Beach
- Cabo marina
- Day4
Loreto
Arrive 08:00 · Depart 17:00
- Day5
Guaymas
Arrive 08:00 · Depart 15:00
- Day6
Topolobampo
Arrive 04:00 · Depart 23:00
- Day7
La Paz
Arrive 08:00 · Depart 17:00
- Day8
Mazatlán
Arrive 10:00 · Depart 18:00
A Pacific-coast resort city in Sinaloa, Mexico, strung along one of the longest seafront promenades in the country. The old town centres on the cathedral and Plaza Machado, while the Golden Zone draws beachgoers and the working harbour still lands shrimp.
- El Malecón
- Old Mazatlán
- Stone Island
- Day9
Puerto Vallarta
Arrive 08:00 · Depart 18:00
A resort city on Mexico's Pacific coast, set where the Sierra Madre meets Banderas Bay. Its cobbled Zona Romántica and the seaside Malecón promenade anchor an old town of churches and galleries, with whale-watching in the bay through the winter months.
- The Malecón
- Zona Romántica
- Banderas Bay
- Day10At sea
- Day11At sea
- Day12
Ensenada
Arrive 08:00 · Depart 17:00
A port city on the Pacific coast of Mexico's Baja California, the peninsula's first stop south of the US border. Its waterfront leads to a famed cantina and a market street, with the La Bufadora marine blowhole on the headland nearby.
- La Bufadora
- Hussong's Cantina
- Coastal wineries
- Day13
San Diego, California
Arrive 07:00
A relaxed harbour city in southern California, known for its mild climate and broad natural bay. The waterfront holds the historic Gaslamp Quarter and maritime museums, with the green expanse of Balboa Park and its zoo just inland.
- Balboa Park
- Gaslamp Quarter
- San Diego Zoo
Upcoming departures
- 7 Dec 2026
- 6 Dec 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
12-Night Americas Cruise from San Diego, California FAQ
Which ports does this cruise visit?
This 12-night Americas cruise calls at San Diego, California, Cabo San Lucas, Loreto, Guaymas, Topolobampo, La Paz, Mazatlán, Puerto Vallarta and Ensenada.
How many days are spent at sea?
3 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It is a round-trip sailing from San Diego, California.
How long is this cruise?
12 nights aboard Zaandam.
When does this itinerary sail?
Upcoming departures include 7 Dec 2026 and 6 Dec 2027. A NestCruise advisor can confirm current availability.