Cruises from San Diego, California
78 live cruises sail from San Diego, California — 4 to 31 nights, across 7 lines, through the Pacific. A NestCruise advisor narrows them to the one that fits.
AmericasRoyal Caribbean International
4 nights: Ensenada
Aboard Serenade of the Seas
Round-trip from San Diego
from$219pp · cruise fare≈ $55/night pp
Fares checked nightly
BAJADisney Cruise Line
4 nights: Ensenada
Aboard Disney Wonder
Round-trip from San Diego
Mexican RivieraNorwegian Cruise Line
7 nights: Cabo San Lucas & Puerto Vallarta, the Mexican Riviera
Aboard Norwegian Star
Round-trip from San Diego
from$449pp · cruise fare≈ $64/night pp
Fares checked nightly
AmericasHolland America Line
7 nights: Cabo San Lucas, South America
Aboard Koningsdam
Round-trip from San Diego
AmericasHolland America Line
7 nights: Cabo San Lucas, South America
Aboard Zaandam
Round-trip from San Diego
AmericasHolland America Line
16 nights: Cabo San Lucas & Aruba, South America
Aboard Eurodam
San Diego → Fort Lauderdale
AmericasCrystal
The South America loop
Aboard Crystal Serenity
Round-trip from San Diego
from$5,600pp · cruise fare≈ $622/night pp
Fares checked nightly
ALASKA N ADisney Cruise Line
4 nights: Vancouver
Aboard Disney Magic
San Diego → Vancouver
PacificHolland America Line
4 nights: Vancouver
Aboard Nieuw Amsterdam
San Diego → Vancouver
PacificHolland America Line
6 nights: Seattle & Vancouver
Aboard Oosterdam
San Diego → Vancouver
AmericasHolland America Line
7 nights: Cabo San Lucas, South America
Aboard Zuiderdam
Round-trip from San Diego
AmericasCrystal
8 nights: Juneau & Skagway, Alaska
Aboard Crystal Symphony
San Diego → Vancouver
from$4,200pp · cruise fare≈ $525/night pp
Fares checked nightly
AmericasAzamara
17 nights: Cabo San Lucas, South America
Aboard Azamara Quest
San Diego → Miami
from$4,159pp · cruise fare≈ $245/night pp
Fares checked nightly
World CruiseSilversea
18 nights: Honolulu & Tokyo
Aboard Silver Whisper
San Diego → Singapore
from$14,600pp · cruise fare≈ $811/night pp
Fares checked nightly
AmericasRoyal Caribbean International
3 nights: Ensenada
Aboard Serenade of the Seas
Round-trip from San Diego
from$219pp · cruise fare≈ $73/night pp
Fares checked nightly
BAJADisney Cruise Line
MEXICAN RIVIERA
Aboard Disney Wonder
MEXICAN RIVIERA
Mexican RivieraNorwegian Cruise Line
6 nights: Puerto Vallarta & Cabo San Lucas, the Mexican Riviera
Aboard Norwegian Star
Round-trip from San Diego
from$479pp · cruise fare≈ $80/night pp
Fares checked nightly
AmericasHolland America Line
7 nights: Cabo San Lucas & Puerto Vallarta, South America
Aboard Koningsdam
Round-trip from San Diego
AmericasHolland America Line
12 nights: Cabo San Lucas & Puerto Vallarta, South America
Aboard Zaandam
Round-trip from San Diego
PacificHolland America Line
6 nights: Vancouver
Aboard Eurodam
San Diego → Vancouver
AmericasCrystal
11 nights: Puerto Vallarta
Aboard Crystal Serenity
San Diego → New York
from$5,000pp · cruise fare≈ $455/night pp
Fares checked nightly
PANAMA CANAL EDisney Cruise Line
14 nights: Cabo San Lucas & Puerto Vallarta
Aboard Disney Magic
San Diego → Galveston
South AmericaHolland America Line
21 nights: Cabo San Lucas, South America
Aboard Nieuw Amsterdam
San Diego → San Antonio
AmericasHolland America Line
7 nights: Cabo San Lucas, South America
Aboard Zuiderdam
Round-trip from San Diego
West Coast USCrystal
San Diego to Vancouver
Aboard Crystal Symphony
San Diego to Vancouver
from$9,200pp · cruise fare≈ $511/night pp
Fares checked nightly
TranspacificAzamara
35 nights: Cabo San Lucas, the Pacific crossing
Aboard Azamara Quest
San Diego → Tilbury
from$12,009pp · cruise fare≈ $343/night pp
Fares checked nightly
AmericasRoyal Caribbean International
7 nights: Cabo San Lucas & Ensenada
Aboard Serenade of the Seas
Round-trip from San Diego
from$419pp · cruise fare≈ $60/night pp
Fares checked nightly
BAJADisney Cruise Line
3 nights: Ensenada
Aboard Disney Wonder
Round-trip from San Diego
Panama CanalNorwegian Cruise Line
16 nights: Cabo San Lucas, the Panama Canal
Aboard Norwegian Star
San Diego → Miami
from$1,709pp · cruise fare≈ $107/night pp
Fares checked nightly
AmericasHolland America Line
10 nights: Cabo San Lucas & Puerto Vallarta, South America
Aboard Koningsdam
Round-trip from San Diego
AmericasHolland America Line
15 nights: Cabo San Lucas & Puerto Vallarta, South America
Aboard Zaandam
San Diego → Fort Lauderdale
AmericasCrystal
15 nights: Singapore & Hong Kong
Aboard Crystal Serenity
San Diego → Vancouver
from$7,300pp · cruise fare≈ $487/night pp
Fares checked nightly
South AmericaHolland America Line
36 nights: Cabo San Lucas & Buenos Aires, South America
Aboard Nieuw Amsterdam
San Diego → Buenos Aires
AmericasHolland America Line
14 nights: Cabo San Lucas, South America
Aboard Zuiderdam
Round-trip from San Diego
AmericasRoyal Caribbean International
7 nights: Cabo San Lucas
Aboard Serenade of the Seas
Round-trip from San Diego
from$419pp · cruise fare≈ $60/night pp
Fares checked nightly
BAJADisney Cruise Line
4 nights: Ensenada
Aboard Disney Wonder
Round-trip from San Diego
HawaiiHolland America Line
17 nights: Honolulu & Ensenada, the Hawaiian Islands
Aboard Koningsdam
Round-trip from San Diego
HawaiiHolland America Line
18 nights: Honolulu & Ensenada, the Hawaiian Islands
Aboard Zaandam
Round-trip from San Diego
West Coast USCrystal
Roundtrip San Diego, California
Aboard Crystal Serenity
Roundtrip San Diego, California
from$13,100pp · cruise fare≈ $728/night pp
Fares checked nightly
AmericasHolland America Line
15 nights: Puerto Vallarta, South America
Aboard Zuiderdam
San Diego → Miami
AmericasRoyal Caribbean International
7 nights: Ensenada & Cabo San Lucas
Aboard Serenade of the Seas
Round-trip from San Diego
from$399pp · cruise fare≈ $57/night pp
Fares checked nightly
BAJADisney Cruise Line
3 nights: Ensenada
Aboard Disney Wonder
Round-trip from San Diego
PacificHolland America Line
4 nights: Vancouver
Aboard Koningsdam
San Diego → Vancouver
PacificHolland America Line
30 nights: Honolulu & Cabo San Lucas
Aboard Zaandam
Round-trip from San Diego
Panama CanalCrystal
25 nights in the Panama Canal
Aboard Crystal Serenity
San Diego to New York
from$10,400pp · cruise fare≈ $416/night pp
Fares checked nightly
AmericasRoyal Caribbean International
7 nights: Seattle & Vancouver
Aboard Serenade of the Seas
San Diego → Vancouver
from$599pp · cruise fare≈ $86/night pp
Fares checked nightly
Frequently asked
- How many cruises from San Diego, California does NestCruise have?
- 78 live sailings, 4 to 31 nights. A NestCruise advisor narrows them to the one that fits.
- Which cruise lines sail from San Diego, California?
- Holland America Line, Disney Cruise Line, Crystal and Royal Caribbean International, among others.
- How long are cruises from San Diego, California?
- Most run 4 to 31 nights.
- How much do cruises from San Diego, California cost?
- NestCruise doesn't publish fares — it's a quote-only concierge. Share your dates and party size and an advisor prices your exact sailing at no cost.