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Cruises to Phnom Penh

82 live cruises call at Phnom Penh — 7 to 22 nights, departing 8 ports, across 4 lines. A NestCruise advisor narrows them to the one that fits.

82 sailings
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9-Night Mekong CruiseMekong

Emerald Cruises

9 nights in Southeast Asia

Aboard Emerald Harmony

Saigon → Siem Reap

Aug 2026 – May 2028Next 12 Aug 2026 · 36 more
7-Night Mekong CruiseMekong

AmaWaterways

7 nights in Southeast Asia

Aboard AmaDara

Siem Reap → Saigon

Aug 2026 – Apr 2028Next 17 Aug 2026 · 34 more
Journey along the MekongAsia

Scenic

15 nights in Asia

Aboard Scenic Spirit

Saigon → Siem Reap

Sails every two weeks, Aug 2026 – Dec 2027
10-Night Mekong CruiseMekong

Avalon Waterways

10 nights in Southeast Asia

Aboard Avalon Saigon

Siem Reap → Saigon

Aug 2026 – Nov 2027Next 10 Aug 2026 · 25 more
7-Night Mekong CruiseMekong

AmaWaterways

7 nights in Southeast Asia

Aboard AmaMaya

Siem Reap → Saigon

Feb 2027 – Apr 2028Next 22 Feb 2027 · 22 more
9-Night Mekong CruiseMekong

Emerald Cruises

9 nights in Southeast Asia

Aboard Emerald Harmony

Siem Reap → Saigon

Sep 2026 – May 2028Next 23 Sep 2026 · 33 more
7-Night Mekong CruiseMekong

AmaWaterways

7 nights in Southeast Asia

Aboard AmaDara

Saigon → Siem Reap

Aug 2026 – Apr 2028Next 10 Aug 2026 · 34 more
7-Night Mekong CruiseMekong

Scenic

7 nights in Southeast Asia

Aboard Scenic Spirit

Saigon → Siem Reap

Sep 2026 – Dec 2027Next 29 Sep 2026 · 20 more
11-Night Mekong CruiseMekong

Avalon Waterways

11 nights in Southeast Asia

Aboard Avalon Saigon

Saigon → Siem Reap

Aug 2026 – Nov 2027Next 3 Aug 2026 · 25 more
7-Night Mekong CruiseMekong

AmaWaterways

7 nights in Southeast Asia

Aboard AmaMaya

Saigon → Siem Reap

Feb 2027 – Apr 2028Next 1 Feb 2027 · 22 more
6-Night Mekong CruiseMekong

Emerald Cruises

6 nights in Southeast Asia

Aboard Emerald Harmony

Phnom Penh → Saigon

Sep 2026 – May 2028Next 26 Sep 2026 · 30 more
Luxury Mekong and Temple Discovery CruiseAsia

Scenic

10 nights in Asia

Aboard Scenic Spirit

Siem Reap → Saigon

Sep 2026 – Nov 2027Next 19 Sep 2026 · 20 more
7-Night Mekong CruiseMekong

Avalon Waterways

7 nights in Southeast Asia

Aboard Avalon Saigon

Phnom Penh → Saigon

Aug 2026 – Dec 2027Next 13 Aug 2026 · 24 more
Charms of the Mekong (Smithsonian Journeys)Asia

AmaWaterways

7 nights in Asia

Aboard AmaMaya

Ho Chi Minh City → Kampong Cham

Rare itinerary
Jan 2027 – Oct 2027Next 18 Jan 2027 · 1 more
7-Night Mekong CruiseMekong

Emerald Cruises

7 nights in Southeast Asia

Aboard Emerald Harmony

Saigon → Siem Reap

Oct 2026 – May 2028Next 3 Oct 2026 · 29 more
18-Night Mekong CruiseMekong

Scenic

18 nights in Southeast Asia

Aboard Scenic Spirit

Hanoi → Siem Reap

Sails monthly, Sep 2026 – Dec 2027
7-Night Mekong CruiseMekong

Avalon Waterways

7 nights in Southeast Asia

Aboard Avalon Saigon

Saigon → Phnom Penh

Aug 2026 – Nov 2027Next 20 Aug 2026 · 23 more
15-Night Mekong CruiseMekong

Emerald Cruises

15 nights in Southeast Asia

Aboard Emerald Harmony

Saigon → Laem Chabang

Sails monthly, Oct 2026 – Apr 2028
14-Night Mekong CruiseMekong

Scenic

14 nights in Southeast Asia

Aboard Scenic Spirit

Hanoi → Siem Reap

Sails monthly, Sep 2026 – Nov 2027
Mekong Discovery (Northbound)Asia

Avalon Waterways

7 nights in Asia

Aboard Avalon Saigon

Ho Chi Minh City → Phnom Penh

Overnight in Phnom Penh
Sails every two weeks, Aug 2026 – Oct 2026
23-Night Mekong CruiseMekong

Emerald Cruises

23 nights in Southeast Asia

Aboard Emerald Harmony

Hanoi → Laem Chabang

Sails monthly, Sep 2026 – Apr 2028
11-Night Mekong CruiseMekong

Scenic

11 nights in Southeast Asia

Aboard Scenic Spirit

Saigon → Siem Reap

Aug 2026 – Dec 2027Next 6 Aug 2026 · 9 more
Fascinating Vietnam, Cambodia & the Mekong River (Southbound)Asia

Avalon Waterways

12 nights in Asia

Aboard Avalon Saigon

Siem Reap → Ho Chi Minh City

Overnight in Siem Reap
Sails every two weeks, Aug 2026 – Oct 2026
13-Night Mekong CruiseMekong

Emerald Cruises

13 nights in Southeast Asia

Aboard Emerald Harmony

Hanoi → Saigon

Sails monthly, Sep 2026 – May 2028
19-Night Mekong CruiseMekong

Scenic

19 nights in Southeast Asia

Aboard Scenic Spirit

Hanoi → Saigon

Oct 2026 – Nov 2027Next 22 Oct 2026 · 10 more
Fascinating Vietnam, Cambodia & the Mekong River (Northbound)Asia

Avalon Waterways

12 nights in Asia

Aboard Avalon Saigon

Ho Chi Minh City → Siem Reap

Overnight in Ho Chi Minh City
Sails every two weeks, Aug 2026 – Oct 2026
19-Night Mekong CruiseMekong

Emerald Cruises

19 nights in Southeast Asia

Aboard Emerald Harmony

Hanoi → Saigon

Sails monthly, Aug 2026 – Mar 2028
Temple Discovery and Meandering along the Mekong CruiseAsia

Scenic

12 nights in Asia

Aboard Scenic Spirit

Siem Reap → Saigon

Aug 2026 – Dec 2027Next 14 Aug 2026 · 7 more
Fascinating Vietnam, Cambodia & the Mekong River with Bangkok (Southbound)Asia

Avalon Waterways

15 nights: Bangkok, Asia

Aboard Avalon Saigon

Siem Reap → Bangkok

Overnight in Siem Reap
Sails every two weeks, Aug 2026 – Oct 2026
17-Night Mekong CruiseMekong

Emerald Cruises

17 nights in Southeast Asia

Aboard Emerald Harmony

Hanoi → Saigon

Sep 2026 – Apr 2028Next 29 Sep 2026 · 16 more
15-Night Mekong CruiseMekong

Scenic

15 nights in Southeast Asia

Aboard Scenic Spirit

Hanoi → Saigon

Oct 2026 – Oct 2027Next 12 Oct 2026 · 8 more
Fascinating Vietnam, Cambodia & the Mekong River with Hanoi & Ha Long Bay (Southbound)Asia

Avalon Waterways

15 nights: Ha Long Bay, Asia

Aboard Avalon Saigon

Hanoi → Ho Chi Minh City

Overnight in Hanoi
Sails every two weeks, Aug 2026 – Oct 2026
8-Night Mekong CruiseMekong

Emerald Cruises

8 nights in Southeast Asia

Aboard Emerald Harmony

Phnom Penh → Saigon

Aug 2026 – Dec 2027Next 3 Aug 2026 · 8 more
17-Night Mekong CruiseMekong

Scenic

17 nights in Southeast Asia

Aboard Scenic Spirit

Saigon → Laem Chabang

Sails monthly, Sep 2026 – Mar 2027
Fascinating Vietnam, Cambodia & the Mekong River with Hanoi & Ha Long Bay (Northbound)Asia

Avalon Waterways

15 nights: Ha Long Bay, Asia

Aboard Avalon Saigon

Hanoi → Siem Reap

Overnight in Hanoi
Sails every two weeks, Aug 2026 – Oct 2026
11-Night Mekong CruiseMekong

Emerald Cruises

11 nights in Southeast Asia

Aboard Emerald Harmony

Siem Reap → Saigon

Aug 2026 – Dec 2027Next 18 Aug 2026 · 7 more
26-Night Mekong CruiseMekong

Scenic

26 nights in Southeast Asia

Aboard Scenic Spirit

Hanoi → Laem Chabang

Sails monthly, Sep 2026 – Mar 2027
Fascinating Vietnam, Cambodia & the Mekong River with Bangkok (Northbound)Asia

Avalon Waterways

15 nights: Bangkok, Asia

Aboard Avalon Saigon

Ho Chi Minh City → Bangkok

Overnight in Ho Chi Minh City
Sails every two weeks, Aug 2026 – Oct 2026
11-Night Mekong CruiseMekong

Emerald Cruises

11 nights in Southeast Asia

Aboard Emerald Harmony

Saigon → Siem Reap

Aug 2026 – Dec 2027Next 10 Aug 2026 · 7 more
Luxury Mekong and Temple Discovery CruiseAsia

Scenic

10 nights in Asia

Aboard Scenic Spirit

Siem Reap → Ho Chi Minh City

Overnight in Siem Reap
Sails weekly, Sep 2026 – Oct 2026
Fascinating Vietnam, Cambodia & the Mekong River with Hanoi, Ha Long Bay & Bangkok (Southbound)Asia

Avalon Waterways

18 nights: Ha Long Bay & Bangkok, Asia

Aboard Avalon Saigon

Hanoi → Bangkok

Overnight in Hanoi
Sails every two weeks, Aug 2026 – Oct 2026
15-Night Mekong CruiseMekong

Emerald Cruises

15 nights in Southeast Asia

Aboard Emerald Harmony

Hanoi → Saigon

Aug 2026 – Dec 2027Next 14 Aug 2026 · 7 more
Luxury Mekong and Temple Discovery CruiseAsia

Scenic

10 nights in Asia

Aboard Scenic Spirit

Siem Reap → Ho Chi Minh City

Overnight in Siem Reap
Sails weekly, Sep 2026 – Oct 2026
Fascinating Vietnam, Cambodia & the Mekong River with Hanoi, Ha Long Bay & Bangkok (Northbound)Asia

Avalon Waterways

18 nights: Ha Long Bay & Bangkok, Asia

Aboard Avalon Saigon

Hanoi → Bangkok

Overnight in Hanoi
Sails every two weeks, Aug 2026 – Oct 2026
8-Day Majestic Mekong CruiseAsia

Emerald Cruises

7 nights in Asia

Aboard Emerald Harmony

Phnom Penh → Ho Chi Minh City

Sails weekly, Sep 2026 – Nov 2026
Meandering along the Mekong and Temple Discovery CruiseAsia

Scenic

12 nights in Asia

Aboard Scenic Spirit

Ho Chi Minh City → Siem Reap

Overnight in Phnom Penh
Sails monthly, Aug 2026 – Dec 2026
10-Day Meandering Majestic Mekong CruiseAsia

Emerald Cruises

9 nights in Asia

Aboard Emerald Harmony

Phnom Penh → Ho Chi Minh City

Overnight in Phnom Penh
Aug 2026 – Sep 2026Next 3 Aug 2026 · 5 more
Temple Discovery and Meandering along the Mekong CruiseAsia

Scenic

12 nights in Asia

Aboard Scenic Spirit

Ho Chi Minh City → Siem Reap

Overnight in Ho Chi Minh City
Aug 2026 – Sep 2026Next 6 Aug 2026 · 3 more

Frequently asked

How many cruises to Phnom Penh does NestCruise have?
82 live sailings, 7 to 22 nights. A NestCruise advisor narrows them to the one that fits.
Which cruise lines visit Phnom Penh?
Scenic, Emerald Cruises, Avalon Waterways and AmaWaterways, among others.
How long are cruises to Phnom Penh?
Most run 7 to 22 nights.
How much do cruises to Phnom Penh cost?
NestCruise doesn't publish fares — it's a quote-only concierge. Share your dates and party size and an advisor prices your exact sailing at no cost.