Cruise itinerary
16-Night Mekong Cruise from Hanoi
16 nights · Mekong · 11 ports of call
16-night Mekong cruise aboard Scenic Spirit, departing Hanoi and calling at Cat Ba Island Vietnam, Saigon, Cái Bè, Sa Déc, Tân Châu and Phnom Penh and 4 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Scenic Spirit
- Cruise line
- Scenic
- Duration
- 16 nights
- Region
- Mekong · Southeast Asia
- Departs
- Hanoi
- Returns
- Siem Reap
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Scenic Spirit sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1
Hanoi
Vietnam's capital, set inland on the Red River and reached by ship via the port of Hai Phong. Its Old Quarter is a maze of trade streets around Hoan Kiem Lake, layered with French-colonial boulevards and centuries of dynastic history.
- Old Quarter
- Hoan Kiem Lake
- Temple of Literature
- Day2At sea
- Day3
Cat Ba Island Vietnam
- Day4At sea
- Day5
Hanoi
Vietnam's capital, set inland on the Red River and reached by ship via the port of Hai Phong. Its Old Quarter is a maze of trade streets around Hoan Kiem Lake, layered with French-colonial boulevards and centuries of dynastic history.
- Old Quarter
- Hoan Kiem Lake
- Temple of Literature
- Day6
Saigon
- Day7At sea
- Day8At sea
- Day9
Cái Bè
- Day10
Sa Déc
- Day11
Tân Châu
A riverside town in An Giang Province on the Mekong Delta in southern Vietnam, near the Cambodian border. Tân Châu is known for its silk-weaving tradition, floating fish farms, and as a quiet stop on Mekong river cruises.
- Silk weaving
- Mekong fish farms
- Delta villages
- Day12
Phnom Penh
Cambodia's capital, set where the Mekong and Tonlé Sap rivers meet. Once styled the Pearl of Asia, it keeps grand French-colonial avenues alongside the gilded Royal Palace, the Silver Pagoda and the sobering history of the Tuol Sleng museum.
- Royal Palace
- Silver Pagoda
- Mekong riverfront
- Day13At sea
- Day14
Phnom Penh
Cambodia's capital, set where the Mekong and Tonlé Sap rivers meet. Once styled the Pearl of Asia, it keeps grand French-colonial avenues alongside the gilded Royal Palace, the Silver Pagoda and the sobering history of the Tuol Sleng museum.
- Royal Palace
- Silver Pagoda
- Mekong riverfront
- Day15
Angkor Ban
- Day16
Kampong Cham
A riverside provincial town on the Mekong in eastern Cambodia, long a trading and rubber-growing hub. Nearby stand the hilltop temples of Phnom Pros and Phnom Srei and the early Angkorian shrine of Wat Nokor.
- Wat Nokor
- Bamboo bridge
- Mekong riverfront
- Day17
Siem Reap
The Cambodian town that serves as gateway to the temples of Angkor, the vast Khmer complex set in jungle to the north. Angkor Wat and the stone faces of the Bayon draw visitors, while the town itself centres on river markets and Pub Street.
- Angkor Wat
- Bayon faces
- Ta Prohm
Upcoming departures
- 14 Jul 2026
- 19 Aug 2026
- 1 Dec 2026
- 13 Jul 2027
- 18 Aug 2027
- 2 Dec 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
16-Night Mekong Cruise from Hanoi FAQ
Which ports does this cruise visit?
This 16-night Mekong cruise calls at Hanoi, Cat Ba Island Vietnam, Saigon, Cái Bè, Sa Déc, Tân Châu, Phnom Penh, Oudong, Angkor Ban, Kampong Cham and Siem Reap.
How many days are spent at sea?
5 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Hanoi and ends in Siem Reap.
How long is this cruise?
16 nights aboard Scenic Spirit.
When does this itinerary sail?
Upcoming departures include 14 Jul 2026, 19 Aug 2026, 1 Dec 2026 and 13 Jul 2027. A NestCruise advisor can confirm current availability.