

Cruise itinerary
10-Night Mekong Cruise from Siem Reap
10 nights · Mekong · 7 ports of call
10-night Mekong cruise aboard Avalon Saigon, departing Siem Reap and calling at Angkor Ban, Phnom Penh, Chau Doc, Long Khanh Island Vietnam, Vinh Long and Saigon.
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- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Avalon Saigon
- Cruise line
- Avalon Waterways
- Duration
- 10 nights
- Region
- Mekong · Southeast Asia
- Departs
- Siem Reap
- Returns
- Saigon
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Avalon Saigon sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Siem Reap
The Cambodian town that serves as gateway to the temples of Angkor, the vast Khmer complex set in jungle to the north. Angkor Wat and the stone faces of the Bayon draw visitors, while the town itself centres on river markets and Pub Street.
- Angkor Wat
- Bayon faces
- Ta Prohm
- Day2At sea
- Day3At sea
- Day4At sea
- Day5

Angkor Ban
- Day6

Phnom Penh
Cambodia's capital, set where the Mekong and Tonlé Sap rivers meet. Once styled the Pearl of Asia, it keeps grand French-colonial avenues alongside the gilded Royal Palace, the Silver Pagoda and the sobering history of the Tuol Sleng museum.
- Royal Palace
- Silver Pagoda
- Mekong riverfront
- Day7At sea
- Day8
Chau Doc
- Day9
Long Khanh Island Vietnam
- Day10

Vinh Long
- Day11
Saigon
Upcoming departures
- 10 Aug 2026
- 24 Aug 2026
- 7 Sep 2026
- 21 Sep 2026
- 5 Oct 2026
- 19 Oct 2026
- 2 Nov 2026
- 16 Nov 2026
- 30 Nov 2026
- 11 Jan 2027
- 25 Jan 2027
- 8 Feb 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
10-Night Mekong Cruise from Siem Reap FAQ
Which ports does this cruise visit?
This 10-night Mekong cruise calls at Siem Reap, Angkor Ban, Phnom Penh, Chau Doc, Long Khanh Island Vietnam, Vinh Long and Saigon.
How many days are spent at sea?
4 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Siem Reap and ends in Saigon.
How long is this cruise?
10 nights aboard Avalon Saigon.
When does this itinerary sail?
Upcoming departures include 10 Aug 2026, 24 Aug 2026, 7 Sep 2026 and 21 Sep 2026. A NestCruise advisor can confirm current availability.