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Cruises from Valletta

42 live cruises sail from Valletta — 6 to 10 nights, across 8 lines, through Europe. A NestCruise advisor narrows them to the one that fits.

42 sailings
MSC SeaviewEurope

MSC Cruises

Malta, Spain, France, Italy

Aboard MSC Seaview

Valletta → Barcelona → Marseille → Genoa +2 more

7 nights · 6 departures

Port-rich · 6 ports

Apr 2027 – May 2027View details →
MSC SplendidaEurope

MSC Cruises

Malta, Spain, France, Italy

Aboard MSC Splendida

Valletta → Barcelona → Marseille → Livorno +2 more

7 nights · 4 departures

Port-rich · 6 ports

Jun 2026 – Jul 2026View details →
MSC World AsiaEurope

MSC Cruises

Valletta, Barcelona, Marseille, Genoa, Civitavecchia, Messina, Valletta

Aboard MSC World Asia

Valletta → Barcelona → Marseille → Genoa +2 more

7 nights · 6 departures

Port-rich · 6 ports

Dec 2026 – Jan 2027View details →
MSC World EuropaEurope

MSC Cruises

Valletta, Barcelona, Marseille, Genoa, Naples, Messina, Valletta

Aboard MSC World Europa

Valletta → Barcelona → Marseille → Genoa +2 more

7 nights · 3 departures

Port-rich · 6 ports

Jun 2026 – Jul 2026View details →
Silver ShadowEurope

Silversea

Valletta to Nice

Aboard Silver Shadow

Valletta → Taormina → Salerno → Gaeta +3 more

6 nights · 4 departures

Port-rich · 7 ports

Jun 2026 – Aug 2026View details →
Le Dumont-d'UrvilleEurope

PONANT EXPLORATIONS

A Circumnavigation of Sicily – with Smithsonian Journeys

Aboard Le Dumont-d'Urville

Valletta → Porto Empedocle → Tunis → Trapani, Sicily +5 more

8 nights · 2 departures

Port-rich · 9 ports

Aug 2026 – May 2027View details →
Emerald AzzurraEurope

Emerald Cruises

Mediterranean crossroads

Aboard Emerald Azzurra

Valletta → Siracuse, Sicily → Giardini Naxos → Fiskárdo +7 more

10 nights · 2 departures

Port-rich · 11 ports

May 2027 – Oct 2028View details →
Crystal SerenityEurope

Crystal

La Valletta to Civitavecchia (Rome)

Aboard Crystal Serenity

Valletta → Trapani, Sicily → Cagliari → Civitavecchia

3 nights · 1 departure

Port-rich · 4 ports

Sep 2026View details →
EXPLORA IIEurope

Explora Journeys

A Journey of Crossroads, Culture and Eternal Echoes

Aboard EXPLORA II

Valletta → Tunis → Palermo → At Sea +1 more

4 nights · 1 departure

Port-rich · 5 ports

Jan 2027View details →
Crystal SymphonyEurope

Crystal

Valletta to Barcelona

Aboard Crystal Symphony

Valletta → Tunis → Cagliari → At Sea +4 more

7 nights · 1 departure

Port-rich · 8 ports

May 2027View details →
Le BoréalEurope

PONANT EXPLORATIONS

Cruising the Mediterranean: Sicily, Sardinia, and Mallorca – with Smithsonian Journeys

Aboard Le Boréal

Valletta → Trapani, Sicily → Palermo → Cagliari +4 more

7 nights · 1 departure

Port-rich · 8 ports

Oct 2026View details →
Le BougainvilleEurope

PONANT EXPLORATIONS

Authentic Mediterranean Shores

Aboard Le Bougainville

Valletta → Trapani, Sicily → Palermo → Lipari +3 more

7 nights · 1 departure

Port-rich · 7 ports

Apr 2027View details →
Silver MuseEurope

Silversea

Valletta to Lisbon

Aboard Silver Muse

Valletta → Trapani, Sicily → Cagliari → At Sea +3 more

7 nights · 1 departure

Port-rich · 7 ports

Oct 2026View details →
Le LapérouseEurope

PONANT EXPLORATIONS

A Circumnavigation of Sicily – with Smithsonian Journeys

Aboard Le Lapérouse

Valletta → Porto Empedocle → Tunis → Trapani, Sicily +5 more

8 nights · 1 departure

Port-rich · 9 ports

Oct 2027View details →
Emerald SakaraEurope

Emerald Cruises

Malta, Sicily & Amalfi Coast

Aboard Emerald Sakara

Valletta → Giardini Naxos → Messina Straits Sicily,, Italy → Lipari +6 more

9 nights · 1 departure

Port-rich · 10 ports

Jul 2026View details →
Le ChamplainEurope

PONANT EXPLORATIONS

Ancient shores of the Mediterranean

Aboard Le Champlain

Valletta → Siracuse, Sicily → Porto Empedocle → Tunis +6 more

9 nights · 1 departure

Port-rich · 10 ports

Nov 2026View details →
Oceania SirenaEurope

Oceania Cruises

Romantic Mediterranean

Aboard Oceania Sirena

Valletta → Catania → Sorrento → Civitavecchia +7 more

10 nights · 1 departure

Port-rich · 11 ports

Sep 2026View details →
Seven Seas GrandeurEurope

Regent Seven Seas Cruises

Beauty Under The Stars

Aboard Seven Seas Grandeur

Valletta → Cruising the Mediterranean Sea → Catania → Gallipoli +8 more

12 nights · 1 departure

Port-rich · 12 ports

Oct 2026View details →
Oceania AlluraAtlantic

Oceania Cruises

Moroccan & Spanish Delights

Aboard Oceania Allura

Valletta → La Goulette → At Sea → Cartagena +9 more

14 nights · 1 departure

Port-rich · 13 ports

Aug 2026View details →
MSC World AsiaEurope

MSC Cruises

Valletta, Barcelona, Marseille, Genoa, Naples, Messina, Valletta

Aboard MSC World Asia

Valletta → Barcelona → Marseille → Genoa +2 more

7 nights · 6 departures

Port-rich · 6 ports

Apr 2027 – May 2027View details →
MSC World EuropaEurope

MSC Cruises

Malta, Spain, France, Italy

Aboard MSC World Europa

Valletta → Barcelona → Marseille → Genoa

4 nights · 1 departure

Port-rich · 4 ports

Nov 2026View details →
Le Dumont-d'UrvilleEurope

PONANT EXPLORATIONS

Ancient shores of the Mediterranean

Aboard Le Dumont-d'Urville

Valletta → Siracuse, Sicily → Porto Empedocle → Tunis +6 more

9 nights · 2 departures

Port-rich · 10 ports

Oct 2026 – Nov 2027View details →
Emerald AzzurraEurope

Emerald Cruises

Discover the Charming Mediterranean

Aboard Emerald Azzurra

Valletta → Siracuse, Sicily → Giardini Naxos → Fiskárdo +11 more

17 nights · 1 departure

Port-rich · 15 ports

May 2027View details →
EXPLORA IIEurope

Explora Journeys

A Journey to the Aegean’s Sacred and Sunlit Isles

Aboard EXPLORA II

Valletta → At Sea → Mykonos → Pátmos +2 more

5 nights · 1 departure

Port-rich · 6 ports

Mar 2027View details →
Crystal SymphonyEurope

Crystal

Valletta to Barcelona

Aboard Crystal Symphony

Valletta → Tunis → Trapani, Sicily → Lipari +4 more

9 nights · 1 departure

Port-rich · 8 ports

May 2028View details →
Le BoréalEurope

PONANT EXPLORATIONS

Authentic Mediterranean Shores

Aboard Le Boréal

Valletta → Porto Empedocle → Trapani, Sicily → Palermo +5 more

8 nights · 1 departure

Port-rich · 9 ports

Jun 2027View details →
Le BougainvilleEurope

PONANT EXPLORATIONS

A Celebration of Art Featuring the 61st Venice Biennale

Aboard Le Bougainville

Valletta → Siracuse, Sicily → Otranto → Bari +3 more

8 nights · 1 departure

Port-rich · 7 ports

Jul 2026View details →
Le LapérouseEurope

PONANT EXPLORATIONS

Peaceful islands and ancient treasures of the Mediterranean

Aboard Le Lapérouse

Valletta → Taormina → Gallipoli → Parga +6 more

8 nights · 1 departure

Port-rich · 10 ports

Aug 2027View details →
Emerald SakaraEurope

Emerald Cruises

Yachting Sicily to Elba via the Amalfi Coast

Aboard Emerald Sakara

Valletta → Siracuse, Sicily → Giardini Naxos → Lipari +7 more

10 nights · 1 departure

Port-rich · 11 ports

Jun 2027View details →
Le Dumont-d'UrvilleEurope

PONANT EXPLORATIONS

The Mediterranean: in the Footsteps of Great Civilisations

Aboard Le Dumont-d'Urville

Valletta → Siracuse, Sicily → Gallipoli → Corfu +8 more

10 nights · 2 departures

Port-rich · 12 ports

Apr 2027View details →
Le BoréalEurope

PONANT EXPLORATIONS

Authentic Mediterranean shores

Aboard Le Boréal

Valletta → Porto Empedocle → Trapani, Sicily → Palermo +6 more

9 nights · 1 departure

Port-rich · 10 ports

Oct 2026View details →
Le BougainvilleEurope

PONANT EXPLORATIONS

6th Opera Festival at Sea, with Benjamin Bernheim

Aboard Le Bougainville

Valletta → Siracuse, Sicily → Otranto → Kotor +4 more

8 nights · 1 departure

Port-rich · 8 ports

May 2027View details →
Le LapérouseEurope

PONANT EXPLORATIONS

Ancient shores of the Mediterranean

Aboard Le Lapérouse

Valletta → Siracuse, Sicily → Porto Empedocle → Tunis +6 more

9 nights · 1 departure

Port-rich · 10 ports

Oct 2027View details →
Emerald SakaraEurope

Emerald Cruises

Mediterranean delights

Aboard Emerald Sakara

Valletta → Mgarr, Gozo → Porto Empedocle → Mazara del Vallo +6 more

10 nights · 1 departure

Port-rich · 10 ports

Jul 2026View details →
Le Dumont-d'UrvilleEurope

PONANT EXPLORATIONS

Ancient Wonders and Culinary Delights: Cruising Southern Italy and Sicily – with Smithsonian Journeys

Aboard Le Dumont-d'Urville

Valletta → Siracuse, Sicily → Taormina → Reggio di Calabria +4 more

8 nights · 1 departure

Port-rich · 8 ports

Sep 2026View details →
Le BoréalEurope

PONANT EXPLORATIONS

Italian shores and Isle of Beauty

Aboard Le Boréal

Valletta → Siracuse, Sicily → Taormina → Palermo +7 more

9 nights · 1 departure

Port-rich · 11 ports

Jun 2027View details →
Le BougainvilleEurope

PONANT EXPLORATIONS

From Malta to the shores of the Adriatic

Aboard Le Bougainville

Valletta → Taormina → Otranto → Sailing in the Bay of Kotor +8 more

8 nights · 1 departure

Port-rich · 12 ports

Aug 2027View details →
Emerald SakaraEurope

Emerald Cruises

Discover Coastal Shores and Hidden Gems

Aboard Emerald Sakara

Valletta → Siracuse, Sicily → Giardini Naxos → Lipari +15 more

17 nights · 1 departure

Port-rich · 19 ports

Jun 2027View details →
Le Dumont-d'UrvilleEurope

PONANT EXPLORATIONS

Peaceful islands and ancient treasures of the Mediterranean

Aboard Le Dumont-d'Urville

Valletta → Taormina → Gallipoli → Parga +6 more

8 nights · 1 departure

Port-rich · 10 ports

Jun 2027View details →
Le BougainvilleEurope

PONANT EXPLORATIONS

Ancient shores of the Mediterranean

Aboard Le Bougainville

Valletta → Siracuse, Sicily → Porto Empedocle → Tunis +6 more

9 nights · 1 departure

Port-rich · 10 ports

Oct 2027View details →
Le Dumont-d'UrvilleEurope

PONANT EXPLORATIONS

Mediterranean Island Voyage: Sicily, Sardinia, Corsica, and Elba – with Smithsonian Journeys

Aboard Le Dumont-d'Urville

Valletta → Mgarr, Gozo → Siracuse, Sicily → Taormina +5 more

8 nights · 1 departure

Port-rich · 9 ports

May 2027View details →
Le BougainvilleEurope

PONANT EXPLORATIONS

Ancient shores of the Mediterranean

Aboard Le Bougainville

Valletta → Siracuse, Sicily → Porto Empedocle → Tunis +7 more

10 nights · 1 departure

Port-rich · 11 ports

Oct 2026View details →

Frequently asked

How many cruises from Valletta does NestCruise have?
42 live sailings, 6 to 10 nights. A NestCruise advisor narrows them to the one that fits.
Which cruise lines sail from Valletta?
PONANT EXPLORATIONS, Emerald Cruises, MSC Cruises and Crystal, among others.
How long are cruises from Valletta?
Most run 6 to 10 nights.
How much do cruises from Valletta cost?
NestCruise doesn't publish fares — it's a quote-only concierge. Share your dates and party size and an advisor prices your exact sailing at no cost.