Cruise itinerary
12-Night Europe Cruise from Valletta
12 nights · Europe · 12 ports of call
12-night Europe cruise aboard Seven Seas Grandeur, departing Valletta and calling at Cruising the Mediterranean Sea, Catania, Gallipoli, Dubrovnik, Kotor and Katakolon and 5 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Cruise line
- Regent Seven Seas Cruises
- Duration
- 12 nights
- Region
- Europe · Southern Europe · Mediterranean · Greek Islands · Aegean
- Departs
- Valletta
- Returns
- Piraeus
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Seven Seas Grandeur sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1
Valletta
Arrive 07:00 · Depart 21:00
Malta's fortified harbour capital, built by the Knights of St. John on a peninsula between two deep ports. Honey-coloured limestone defines St. John's Co-Cathedral, the Grand Master's Palace and the bastions overlooking the Grand Harbour.
- Grand Harbour
- St. John's Co-Cathedral
- Upper Barrakka Gardens
- Day2
Cruising the Mediterranean Sea
- Day3
Catania
Arrive 07:00 · Depart 16:00
A port city on the east coast of Sicily, built in dark volcanic stone beneath Mount Etna, Europe's most active volcano. Its baroque centre, rebuilt after earthquakes, is known for the elephant fountain, a fish market, and Etna excursions inland.
- Mount Etna
- Baroque centre
- Fish market
- Day4
Gallipoli
Arrive 07:00 · Depart 16:00
- Day5
Dubrovnik
Arrive 09:00 · Depart 18:00
A walled city on Croatia's Dalmatian coast, its limestone old town wrapped in sea-facing ramparts above the Adriatic. Ships call here for the marble main street of Stradun, the circuit of the city walls and the cable car to Mount Srđ.
- City walls
- Stradun
- Mount Srđ cable car
- Day6
Kotor
Arrive 07:00 · Depart 13:00
A walled medieval town at the head of the Bay of Kotor, a fjord-like inlet of the Adriatic ringed by steep mountains. Ships anchor below the old town, whose stone lanes and ramparts climb toward the fortress of San Giovanni.
- Bay of Kotor
- Old town walls
- San Giovanni fortress
- Day7
Katakolon
Arrive 13:00 · Depart 21:00
A small port on Greece's western Peloponnese coast, best known as the gateway to ancient Olympia. The sanctuary where the original Olympic Games were held lies a short drive inland, among ruined temples and the old stadium.
- Ancient Olympia
- Olympic stadium
- Temple of Zeus
- Day8
Cruising the Aegean Sea
- Day9
Istanbul
Arrive 10:00
The city straddling Europe and Asia along the Bosphorus, once Byzantium and then Constantinople. Ships dock near the historic peninsula, within reach of the Hagia Sophia, the Blue Mosque and the covered Grand Bazaar's labyrinth of stalls.
- Hagia Sophia
- Blue Mosque
- Grand Bazaar
- Day10
Istanbul
Depart 12:00
The city straddling Europe and Asia along the Bosphorus, once Byzantium and then Constantinople. Ships dock near the historic peninsula, within reach of the Hagia Sophia, the Blue Mosque and the covered Grand Bazaar's labyrinth of stalls.
- Hagia Sophia
- Blue Mosque
- Grand Bazaar
- Day11
Kusadasi
Arrive 10:30 · Depart 20:00
A resort town on Turkey's Aegean coast that serves as the cruise gateway to ancient Ephesus, one of the best-preserved classical cities in the Mediterranean. Pigeon Island guards the harbour, and the marble Library of Celsus lies a short drive inland.
- Ephesus ruins
- Library of Celsus
- Pigeon Island
- Day12
Santorini
Arrive 08:00 · Depart 18:00
The crescent rim of a flooded volcanic caldera in the Greek Cyclades, its whitewashed villages strung along cliffs high above the sea. Fira and Oia draw crowds for sunset views, while the caldera's dark beaches and the ancient site of Akrotiri lie below.
- Oia sunset
- Fira town
- Caldera cliffs
- Day13
Piraeus
Arrive 05:30 · Depart 18:00
The ancient harbour of Athens and Greece's principal cruise port. Ferries fan out to the Aegean islands from its quays, while the Acropolis, the Plaka district and the National Archaeological Museum sit a short metro ride inland.
- Gateway to Athens
- Acropolis
- Aegean ferries
Upcoming departures
- 20 Oct 2026
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
12-Night Europe Cruise from Valletta FAQ
Which ports does this cruise visit?
This 12-night Europe cruise calls at Valletta, Cruising the Mediterranean Sea, Catania, Gallipoli, Dubrovnik, Kotor, Katakolon, Cruising the Aegean Sea, Istanbul, Kusadasi, Santorini and Piraeus.
How many days are spent at sea?
2 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Valletta and ends in Piraeus.
How long is this cruise?
12 nights aboard Seven Seas Grandeur.
When does this itinerary sail?
Upcoming departures include 20 Oct 2026. A NestCruise advisor can confirm current availability.