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Cruises to La Spezia

140 live cruises call at La Spezia — 7 to 25 nights, departing 29 ports, across 13 lines. A NestCruise advisor narrows them to the one that fits.

140 sailings
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Western Mediterranean CruiseEurope

Royal Caribbean International

7 nights: Civitavecchia & Barcelona, the Mediterranean

Aboard Legend of the Seas

Round-trip from Civitavecchia

Sails every two weeks, Aug 2026 – Oct 2027
Spain, France, ItalyEurope

MSC Cruises

7 nights: Barcelona & Civitavecchia, the Mediterranean

Aboard MSC Grandiosa

Round-trip from Barcelona

Sails weekly, Aug 2026 – Oct 2026
Mediterranean with Greece, Italy & TurkeyMediterranean

Princess Cruises

14 nights: Barcelona & Naples, the Mediterranean

Aboard Sun Princess

Barcelona → Piraeus-Athens

Aug 2026 – Oct 2027Next 8 Aug 2026 · 10 more
Italian Riviera, France & SpainEurope

Celebrity Cruises

9 nights: Civitavecchia & Barcelona, the Mediterranean

Aboard Celebrity Equinox

Civitavecchia → Barcelona

Overnight in La Spezia
Aug 2026 – Oct 2027Next 25 Aug 2026 · 8 more
Italian & French RivieraEurope

Celebrity Cruises

7 nights: Barcelona & Civitavecchia, the Mediterranean

Aboard Celebrity Xcel

Round-trip from Barcelona

Aug 2026 – Sep 2027Next 22 Aug 2026 · 6 more
Palma de Mallorca, Barcelona, Marseille, Genoa, La Spezia, Civitavecchia, Palma de MallorcaEurope

MSC Cruises

7 nights: Barcelona & Civitavecchia, the Mediterranean

Aboard MSC World Europa

Round-trip from Palma de Mallorca

Sails weekly, Apr 2027 – Jun 2027
Best of Italy & CroatiaMediterranean

Celebrity Cruises

10 nights: Civitavecchia & Dubrovnik, the Mediterranean

Aboard Celebrity Constellation

Civitavecchia → Ravenna

Jun 2027 – Oct 2027Next 4 Jun 2027 · 6 more
Italy, Spain & French RivieraEurope

Royal Caribbean International

7 nights: Civitavecchia & Barcelona, the Mediterranean

Aboard Explorer of the Seas

Civitavecchia → Barcelona

Sails monthly, May 2027 – Sep 2027
Barcelona → BarcelonaMediterranean & Western Europe

Explora Journeys

14 nights: Barcelona & Civitavecchia

Aboard EXPLORA I

Barcelona → Civitavecchia

Sails monthly, May 2027 – Sep 2027
21-Night Mediterranean CruiseMediterranean

Cunard

21 nights: Barcelona & Dubrovnik, the Mediterranean

Aboard Queen Elizabeth

Round-trip from Civitavecchia-Rome

Jul 2027 – Sep 2027Next 2 Jul 2027 · 4 more
Venetian & Roman RevelryEurope

Oceania Cruises

9 nights: Venice & Barcelona, the Mediterranean

Aboard Oceania Sirena

Venice → Barcelona

Rare itinerary
Apr 2027 – Aug 2027Next 17 Apr 2027 · 2 more
7-Night Mediterranean CruiseMediterranean

Oceania Cruises

7 nights: Civitavecchia & Barcelona, the Mediterranean

Aboard Oceania Allura

Civitavecchia → Barcelona

Rare itinerary
Jul 2027 – Oct 2027Next 2 Jul 2027 · 1 more
Italy & Croatia CruiseEurope

Royal Caribbean International

7 nights: Barcelona & Civitavecchia, the Mediterranean

Aboard Brilliance of the Seas

Barcelona → Ravenna

Rare itinerary
May 2027 – Oct 2027Next 8 May 2027 · 1 more
7-Night Mediterranean CruiseMediterranean

Azamara

7 nights: Barcelona & Civitavecchia, the Mediterranean

Aboard Azamara Onward

Barcelona → Civitavecchia

Rare itinerary
Nov 2026 – Jun 2028Next 28 Nov 2026 · 1 more
Italy, Croatia & FranceEurope

Celebrity Cruises

12 nights: Dubrovnik & Barcelona, the Mediterranean

Aboard Celebrity Infinity

Piraeus → Barcelona

Rare itinerary
Nov 2026 – Oct 2027Next 2 Nov 2026 · 1 more
Mediterranean, Italy & SpainEurope

Celebrity Cruises

14 nights: Civitavecchia & Barcelona, the Mediterranean

Aboard Celebrity Apex

Round-trip from Southampton

Rare itinerary
Sep 2026 – Sep 2027Next 12 Sep 2026 · 1 more
Spain & Portugal TransatlanticTransatlantic

Royal Caribbean International

14 nights: Civitavecchia & Barcelona, the Atlantic crossing

Aboard Odyssey of the Seas

Civitavecchia → Cape Liberty Bayonne

Rare itinerary
Oct 2026 – Oct 2027Next 25 Oct 2026 · 1 more
Barcelona → La VallettaMediterranean & Western Europe

Explora Journeys

6 nights: Barcelona & Mykonos

Aboard EXPLORA II

Barcelona → Piraeus

Rare itinerary
Mar 2027Next 14 Mar 2027
Civitavecchia (Rome) → BarcelonaMediterranean & Western Europe

Explora Journeys

7 nights: Civitavecchia & Barcelona

Aboard EXPLORA VI

Round-trip from Civitavecchia

Rare itinerary
Oct 2028Next 2 Oct 2028
Mediterranean HolidayEurope

Oceania Cruises

7 nights: Barcelona & Naples, the Mediterranean

Aboard Oceania Insignia

Barcelona → Civitavecchia

Rare itinerary
Oct 2026Next 6 Oct 2026
Rome To RomanceEurope

Oceania Cruises

7 nights: Civitavecchia & Barcelona, the Mediterranean

Aboard Oceania Marina

Civitavecchia → Barcelona

Rare itinerary
Apr 2028Next 10 Apr 2028
Best Of Italy & French RivieraEurope

Royal Caribbean International

7 nights: Barcelona & Civitavecchia, the Mediterranean

Aboard Mariner of the Seas

Barcelona → Ravenna

Rare itinerary
Aug 2027Next 6 Aug 2027
Barcelona, Marseille, La Spezia, Naples, Palermo, Valletta, BarcelonaEurope

MSC Cruises

7 nights: Barcelona & Naples, the Mediterranean

Aboard MSC Seaview

Round-trip from Barcelona

Rare itinerary
Nov 2027Next 7 Nov 2027
Regards From The RivieraEurope

Oceania Cruises

7 nights: Civitavecchia & Barcelona, the Mediterranean

Aboard Oceania Nautica

Civitavecchia → Barcelona

Rare itinerary
Sep 2027Next 9 Sep 2027
Relaxation & RomanceEurope

Oceania Cruises

7 nights: Barcelona & Civitavecchia, the Mediterranean

Aboard Oceania Sonata

Barcelona → Civitavecchia

Rare itinerary
Apr 2028Next 1 Apr 2028
Mediterranean SymphonyEurope

Regent Seven Seas Cruises

7 nights: Barcelona & Civitavecchia, the Mediterranean

Aboard Seven Seas Grandeur

Barcelona → Civitavecchia

Rare itinerary
Sep 2028Next 19 Sep 2028
Spellbinding MediterraneanEurope

Regent Seven Seas Cruises

7 nights: Civitavecchia & Marseille, the Mediterranean

Aboard Seven Seas Splendor

Civitavecchia → Lisbon

Rare itinerary
Oct 2027Next 31 Oct 2027
Culinary Towns & VillagesEurope

Regent Seven Seas Cruises

7 nights: Barcelona & Civitavecchia, the Mediterranean

Aboard Seven Seas Voyager

Barcelona → Civitavecchia

Rare itinerary
Nov 2027Next 13 Nov 2027
Spanish, French & Italian ClassicsEurope

Virgin Voyages

8 nights: Barcelona & Cannes, the Mediterranean

Aboard Scarlet Lady

Round-trip from Barcelona

Rare itinerary
Aug 2026Next 2 Aug 2026
8-Night Italy, France & TunisiaMEDITERRANEAN

Seabourn

8 nights: Dubrovnik & Mykonos, the Mediterranean

Aboard Seabourn Ovation

Genoa → Istanbul

Rare itinerary
Apr 2027Next 30 Apr 2027
Civitavecchia (Rome) to BarcelonaEurope

Crystal

9 nights: Civitavecchia & Barcelona, the Mediterranean

Aboard Crystal Symphony

Civitavecchia → Barcelona

Rare itinerary
Jun 2027Next 12 Jun 2027
9-Night Mediterranean CruiseMediterranean

Virgin Voyages

9 nights: Barcelona & Civitavecchia, the Mediterranean

Aboard Resilient Lady

Barcelona → Civitavecchia

Rare itinerary
Aug 2027Next 8 Aug 2027
Italy, Greece & MaltaEurope

Celebrity Cruises

10 nights: Barcelona & Mykonos, the Mediterranean

Aboard Celebrity Eclipse

Barcelona → Piraeus

Rare itinerary
Sep 2027Next 10 Sep 2027
10-Day Greek Isles From Istanbul to Rome: Santorini, Athens & MykonosGreek Isles

Norwegian Cruise Line

10 nights: Istanbul & Santorini

Aboard Norwegian Viva

Istanbul → Civitavecchia

Rare itinerary
Oct 2027Next 13 Oct 2027
Best Of Italy & Greece CruiseEurope

Royal Caribbean International

11 nights: Barcelona & Mykonos, the Mediterranean

Aboard Rhapsody of the Seas

Barcelona → Piraeus

Rare itinerary
May 2027Next 3 May 2027
Poetry In MotionEurope

Regent Seven Seas Cruises

11 nights: Barcelona & Monaco, the Mediterranean

Aboard Seven Seas Explorer

Barcelona → Civitavecchia

Rare itinerary
Aug 2028Next 25 Aug 2028
14-Night Mediterranean CruiseMediterranean

Cunard

14 nights: Marseille & Istanbul, the Mediterranean

Aboard Queen Victoria

Civitavecchia-Rome → Istanbul

Rare itinerary
Sep 2026Next 14 Sep 2026
Acropolis To AmalfiEurope

Regent Seven Seas Cruises

14 nights: Mykonos & Istanbul, the Mediterranean

Aboard Seven Seas Mariner

Piraeus → Barcelona

Rare itinerary
Oct 2026Next 12 Oct 2026
Western Mediterranean CruiseMediterranean

Royal Caribbean International

7 nights: Barcelona & Civitavecchia, the Mediterranean

Aboard Legend of the Seas

Round-trip from Barcelona

Sails every two weeks, Aug 2026 – Oct 2027
Palma de Mallorca, Barcelona, Cannes, Genoa, La Spezia, Civitavecchia, Palma de MallorcaEurope

MSC Cruises

7 nights: Barcelona & Civitavecchia, the Mediterranean

Aboard MSC Grandiosa

Round-trip from Palma de Mallorca

Sails weekly, Aug 2026 – Oct 2026
Mediterranean with Greece, Italy & TurkeyMediterranean

Princess Cruises

14 nights: Barcelona & Naples, the Mediterranean

Aboard Sun Princess

Round-trip from Barcelona

Aug 2026 – Oct 2027Next 29 Aug 2026 · 9 more
Italy, Spain & MaltaEurope

Celebrity Cruises

10 nights: Barcelona & Civitavecchia, the Mediterranean

Aboard Celebrity Equinox

Round-trip from Barcelona

Rare itinerary
Oct 2026Next 20 Oct 2026
Italy & French RivieraEurope

Celebrity Cruises

10 nights: Barcelona & Naples, the Mediterranean

Aboard Celebrity Xcel

Round-trip from Barcelona

Oct 2026 – Oct 2027Next 2 Oct 2026 · 3 more
Civitavecchia, Palma de Mallorca, Barcelona, Marseille, Genoa, La Spezia, CivitavecchiaEurope

MSC Cruises

7 nights: Civitavecchia & Barcelona, the Mediterranean

Aboard MSC World Europa

Round-trip from Civitavecchia

Sails weekly, Apr 2027 – Jun 2027
Best of Italy & CroatiaEurope

Celebrity Cruises

10 nights: Dubrovnik & Kotor, the Mediterranean

Aboard Celebrity Constellation

Ravenna → Civitavecchia

Rare itinerary
Aug 2026 – Oct 2026Next 21 Aug 2026 · 2 more
Civitavecchia (Rome) → BarcelonaMediterranean & Western Europe

Explora Journeys

16 nights: Civitavecchia & Barcelona

Aboard EXPLORA I

Civitavecchia → Barcelona

Rare itinerary
Oct 2026Next 5 Oct 2026
7-Night Mediterranean CruiseMediterranean

Cunard

7 nights: Palma de Mallorca & Barcelona, the Mediterranean

Aboard Queen Elizabeth

Civitavecchia-Rome → Barcelona

Rare itinerary
Aug 2027 – Sep 2027Next 13 Aug 2027 · 2 more
Costa Brave & ItalyEurope

Oceania Cruises

7 nights: Naples & Civitavecchia, the Mediterranean

Aboard Oceania Sirena

Tarragona → Civitavecchia

Rare itinerary
Oct 2026Next 29 Oct 2026

Frequently asked

How many cruises to La Spezia does NestCruise have?
140 live sailings, 7 to 25 nights. A NestCruise advisor narrows them to the one that fits.
Which cruise lines visit La Spezia?
Oceania Cruises, MSC Cruises, Regent Seven Seas Cruises and Cunard, among others.
How long are cruises to La Spezia?
Most run 7 to 25 nights.
How much do cruises to La Spezia cost?
NestCruise doesn't publish fares — it's a quote-only concierge. Share your dates and party size and an advisor prices your exact sailing at no cost.