

Cruise itinerary
21-Night Mediterranean Cruise from Barcelona
21 nights · Mediterranean · 17 ports of call
21-night Mediterranean cruise aboard Sun Princess, departing Barcelona and calling at Palma de Mallorca, Marseille, Ajaccio, Santa Margherita Ligure, Genoa and La Spezia and 10 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Sun Princess
- Cruise line
- Princess Cruises
- Duration
- 21 nights
- Region
- Mediterranean
- Departs
- Barcelona
- Returns
- Barcelona
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Sun Princess sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Barcelona
Depart 17:00
Catalonia's seafront capital and one of the Mediterranean's busiest cruise homeports. Gaudí's Sagrada Família and Park Güell crown the city, while the tree-lined Ramblas and the Gothic Quarter's medieval lanes lie a short ride from the terminal.
- Sagrada Família
- La Rambla
- Gothic Quarter
- Day2

Palma de Mallorca
Arrive 07:00 · Depart 16:00
The capital of Mallorca in Spain's Balearic Islands, set around a wide bay. Its enormous seafront cathedral, La Seu, rises above the old town's narrow lanes, with a hilltop castle, marina and nearby coves a short way from the cruise terminal.
- La Seu cathedral
- Bellver Castle
- Old town
- Day3

Marseille
Arrive 10:00 · Depart 20:00
France's oldest city and biggest Mediterranean port, set around the old harbour of the Vieux-Port. The hilltop basilica of Notre-Dame de la Garde watches over the bay, with the Calanques inlets and bouillabaisse stalls a short way off.
- Vieux-Port
- Notre-Dame de la Garde
- Calanques
- Day4

Ajaccio
Arrive 08:00 · Depart 18:00
The capital of Corsica and Napoleon's birthplace, set on a sheltered gulf on the island's west coast. Ajaccio is known for its Bonaparte family house, the citadel and old town, and the rugged Sanguinaires islands off the harbour mouth.
- Maison Bonaparte
- Sanguinaires islands
- Ajaccio citadel
- Day5

Santa Margherita Ligure
Arrive 07:00 · Depart 19:00
- Day6

Genoa
Arrive 08:00 · Depart 20:00
Italy's great maritime city, stacked up the Ligurian hills above one of the Mediterranean's busiest harbours. Its old town is a maze of tall, narrow caruggi, and it claims pesto and focaccia as local inventions; the Aquarium and Renaissance palaces of Via Garibaldi sit close to the port.
- Old-town caruggi
- Genoa Aquarium
- Via Garibaldi palaces
- Day7

La Spezia
Arrive 07:00 · Depart 19:00
A port at the head of a gulf on Italy's Ligurian coast, the gateway to the Cinque Terre and Tuscany. La Spezia is known for its naval harbour and waterfront gardens, with the five cliffside fishing villages and the marble city of Carrara nearby.
- Cinque Terre
- Portovenere
- Carrara marble
- Day8

Civitavecchia-Rome
Arrive 06:00 · Depart 18:00
The deep-water port serving Rome, roughly 80 kilometres up the coast. Ships dock here for shore excursions to the Colosseum, the Vatican and the Roman Forum, while the town itself keeps a working harbour and a Michelangelo-designed fortress.
- Gateway to Rome
- Fort Michelangelo
- Vatican excursions
- Day9

Naples
Arrive 07:00 · Depart 19:00
A southern Italian port on its namesake bay, in the shadow of Mount Vesuvius. Ships dock near the historic centre, the gateway to Pompeii, the cliffs of the Amalfi Coast and the island of Capri, in a city that claims to have invented pizza.
- Mount Vesuvius
- Pompeii
- Gateway to Capri
- Day10At sea
- Day11

Souda-Chania
Arrive 08:00 · Depart 18:00
The port of Chania on the northwest coast of Crete, set beside Souda Bay, one of the Mediterranean's deepest natural harbours. It opens onto the old Venetian quarter of Chania, with its lighthouse, harbour-front, and lanes of the former Turkish town.
- Chania old town
- Venetian lighthouse
- Souda Bay
- Day12At sea
- Day13

Kusadasi
Arrive 07:00 · Depart 18:00
A resort town on Turkey's Aegean coast that serves as the cruise gateway to ancient Ephesus, one of the best-preserved classical cities in the Mediterranean. Pigeon Island guards the harbour, and the marble Library of Celsus lies a short drive inland.
- Ephesus ruins
- Library of Celsus
- Pigeon Island
- Day14

Mykonos Island
Arrive 07:00 · Depart 21:00
A Cycladic island in the Aegean known for whitewashed houses and a lively summer scene. Ships anchor off the main town, where windmills overlook the sea, the Little Venice quarter meets the waves and sandy beaches stretch along the south coast.
- Windmills
- Little Venice
- Chora town
- Day15

Piraeus-Athens
Arrive 06:00 · Depart 19:00
The ancient harbour of Athens and Greece's principal cruise port. Ferries fan out to the Aegean islands from its quays, while the Acropolis, the Plaka district and the National Archaeological Museum sit a short metro ride inland.
- Gateway to Athens
- Acropolis
- Aegean ferries
- Day16
Heraklion
Arrive 08:00 · Depart 18:00
- Day17At sea
- Day18

Bar Montenegro
Arrive 07:30 · Depart 18:00
- Day19

Corfu Island
Arrive 07:00 · Depart 16:00
An Ionian island off Greece's northwest coast, greener and more Venetian-feeling than the Aegean isles. Ships call at its old town, a UNESCO-listed warren of Italianate streets between two hilltop fortresses, with pebbly coves around the shore.
- Old Fortress
- Liston arcade
- Ionian coves
- Day20

Messina
Arrive 07:00 · Depart 16:00
A Sicilian port on the strait that separates the island from mainland Italy, framed by the Peloritani mountains. Its harbour clock tower performs an elaborate noon display, and the town is a common gateway to Taormina and the slopes of Mount Etna.
- Etna day trips
- Taormina gateway
- Astronomical clock
- Day21At sea
- Day22

Barcelona
Arrive 06:00
Catalonia's seafront capital and one of the Mediterranean's busiest cruise homeports. Gaudí's Sagrada Família and Park Güell crown the city, while the tree-lined Ramblas and the Gothic Quarter's medieval lanes lie a short ride from the terminal.
- Sagrada Família
- La Rambla
- Gothic Quarter
Upcoming departures
- 16 May 2026
- 6 Jun 2026
- 27 Jun 2026
- 18 Jul 2026
- 29 Aug 2026
- 19 Sep 2026
- 10 Oct 2026
- 11 Apr 2027
- 2 May 2027
- 23 May 2027
- 15 Aug 2027
- 5 Sep 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
21-Night Mediterranean Cruise from Barcelona FAQ
Which ports does this cruise visit?
This 21-night Mediterranean cruise calls at Barcelona, Palma de Mallorca, Marseille, Ajaccio, Santa Margherita Ligure, Genoa, La Spezia, Civitavecchia-Rome, Naples, Souda-Chania, Kusadasi, Mykonos Island, Piraeus-Athens, Heraklion, Bar Montenegro, Corfu Island and Messina.
How many days are spent at sea?
4 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It is a round-trip sailing from Barcelona.
How long is this cruise?
21 nights aboard Sun Princess.
When does this itinerary sail?
Upcoming departures include 16 May 2026, 6 Jun 2026, 27 Jun 2026 and 18 Jul 2026. A NestCruise advisor can confirm current availability.