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Cruises to Darién National Park

14 live cruises call at Darién National Park — 7 to 18 nights, departing 6 ports, across 2 lines. A NestCruise advisor narrows them to the one that fits.

14 sailings
Le BellotAmericas

PONANT EXPLORATIONS

Secrets of Central America

Aboard Le Bellot

Colón → Fuerte San Lorenzo → San Blas Islands → Panama Canal Transit +8 more

10 nights · 6 departures

Port-rich · 12 ports

Nov 2026 – Mar 2027View details →
Le LapérouseAmericas

PONANT EXPLORATIONS

Central America Jewels & Panama Canal

Aboard Le Lapérouse

Colón → San Blas Islands → Portobelo → Panama Canal Transit +4 more

7 nights · 3 departures

Port-rich · 8 ports

Jan 2027 – Mar 2027View details →
Le BougainvilleAmericas

PONANT EXPLORATIONS

Secrets of Central America

Aboard Le Bougainville

Colón → Fuerte San Lorenzo → San Blas Islands → Panama Canal Transit +8 more

10 nights · 3 departures

Port-rich · 12 ports

Dec 2027 – Feb 2028View details →
Emerald AzzurraCaribbean

Emerald Cruises

Discover the Secrets of Panama and Costa Rica

Aboard Emerald Azzurra

Bridgetown → Port Elizabeth, Bequia → Mayreau Island → Kralendijk +15 more

18 nights · 3 departures

Port-rich · 19 ports

Jan 2028 – Jan 2029View details →
L'AustralAmericas

PONANT EXPLORATIONS

From Panama’s wild beauty to Peruvian shores

Aboard L'Austral

Colón → San Blas Islands → Panama Canal Transit → Fuerte Amador +4 more

10 nights · 1 departure

Port-rich · 8 ports

Oct 2026View details →
Le BellotAmericas

PONANT EXPLORATIONS

Central America Jewels & Panama Canal

Aboard Le Bellot

Colón → San Blas Islands → Panama Canal Transit → Fuerte Amador +4 more

7 nights · 2 departures

Port-rich · 8 ports

Nov 2026View details →
Le LapérouseAmericas

PONANT EXPLORATIONS

Secrets of Central America

Aboard Le Lapérouse

Colón → Fuerte San Lorenzo → San Blas Islands → Panama Canal Transit +8 more

10 nights · 2 departures

Port-rich · 12 ports

Dec 2026 – Jan 2027View details →
Le BougainvilleAmericas

PONANT EXPLORATIONS

Central America Jewels & Panama Canal

Aboard Le Bougainville

Colón → San Blas Islands → Panama Canal Transit → Fuerte Amador +4 more

7 nights · 2 departures

Port-rich · 8 ports

Dec 2027 – Jan 2028View details →
Emerald AzzurraAmericas

Emerald Cruises

Coastal Adventures: Costa Rica & Panama

Aboard Emerald Azzurra

Puerto Caldera → Curú Wildlife Refuge → Quepos (Puerto Quepos) → Golfito +5 more

7 nights · 2 departures

Port-rich · 9 ports

Feb 2028 – Feb 2029View details →
Le LapérouseAmericas

PONANT EXPLORATIONS

Panama and Costa Rica by Sea: The Natural Wonders of Central America – with Smithsonian Journeys

Aboard Le Lapérouse

Puntarenas → Quepos (Puerto Quepos) → At Sea → Darién National Park +4 more

7 nights · 1 departure

Port-rich · 8 ports

Feb 2027View details →
Emerald AzzurraAmericas

Emerald Cruises

Coastal Adventures: Panama & Costa Rica

Aboard Emerald Azzurra

Panama City → Pearl Islands → Playa Muerto, Darién National Park → Darién National Park +5 more

7 nights · 2 departures

Port-rich · 9 ports

Jan 2028 – Jan 2029View details →
Emerald AzzurraAmericas

Emerald Cruises

Costa Rica, Panama from the Atlantic to the Pacific via the Panama Canal

Aboard Emerald Azzurra

Puerto Caldera → Curú Wildlife Refuge → Quepos (Puerto Quepos) → Golfito +9 more

12 nights · 2 departures

Port-rich · 13 ports

Jan 2028 – Jan 2029View details →
Emerald AzzurraAmericas

Emerald Cruises

Costa Rica, Panama from the Pacific to the Atlantic via the Panama Canal

Aboard Emerald Azzurra

San José → Puerto Limón → Bocas del Toro → Panama Canal Transit +9 more

12 nights · 2 departures

Port-rich · 13 ports

Feb 2028 – Feb 2029View details →
Emerald AzzurraCaribbean

Emerald Cruises

Epic Caribbean Escape: Barbados to Costa Rica

Aboard Emerald Azzurra

Bridgetown → Speightstown → Kingstown → Port Elizabeth, Bequia +19 more

25 nights · 1 departure

Port-rich · 23 ports

Jan 2028View details →

Frequently asked

How many cruises to Darién National Park does NestCruise have?
14 live sailings, 7 to 18 nights. A NestCruise advisor narrows them to the one that fits.
Which cruise lines visit Darién National Park?
PONANT EXPLORATIONS and Emerald Cruises, among others.
How long are cruises to Darién National Park?
Most run 7 to 18 nights.
How much do cruises to Darién National Park cost?
NestCruise doesn't publish fares — it's a quote-only concierge. Share your dates and party size and an advisor prices your exact sailing at no cost.