

Cruise itinerary
36-Night Americas Cruise from Miami, Florida
36 nights · Americas · 25 ports of call
36-night Americas cruise aboard Oceania Insignia, departing Miami, Florida and calling at Key West, Florida, At Sea, Willemstad, Oranjestad, Santa Marta and Cartagena and 18 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Oceania Insignia
- Cruise line
- Oceania Cruises
- Duration
- 36 nights
- Region
- Americas · North America · East Coast US · South America
- Departs
- Miami, Florida
- Returns
- Buenos Aires
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Oceania Insignia sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Miami, Florida
Arrive 07:00 · Depart 17:00
The cruise capital of the world — Miami sends more ships to sea than any port on earth. Most sailings board mid-afternoon, leaving the morning for South Beach, Little Havana or the Wynwood murals before you cast off.
- South Beach
- Little Havana
- Wynwood murals
- Day2

Key West, Florida
Arrive 07:00 · Depart 13:00
The southernmost city in the continental United States, an island town at the end of the Florida Keys. Pastel conch houses line Duval Street, Ernest Hemingway's home is a landmark, and crowds gather at Mallory Square for the nightly sunset.
- Duval Street
- Hemingway House
- Mallory Square sunset
- Day3
At Sea
- Day4
At Sea
- Day5

Willemstad
Arrive 11:00 · Depart 18:00
The capital of Curaçao in the southern Caribbean, with a UNESCO-listed centre of Dutch colonial architecture. Willemstad is known for the candy-coloured waterfront of Handelskade, the swinging Queen Emma pontoon bridge, and its floating market.
- Handelskade façades
- Queen Emma Bridge
- Floating Market
- Day6

Oranjestad
Arrive 07:00 · Depart 16:00
The capital of Aruba, set on the island's leeward south coast in the southern Caribbean. Oranjestad is known for its Dutch colonial façades along Wilhelminastraat, a free streetcar through downtown, and white-sand beaches like Eagle and Palm just north.
- Eagle Beach
- Palm Beach
- Dutch colonial centre
- Day7

Santa Marta
Arrive 09:00 · Depart 18:00
- Day8

Cartagena
Arrive 07:00 · Depart 13:30
A walled colonial city on Colombia's Caribbean coast, its old town a maze of pastel houses, balconies and shaded plazas. Massive stone ramparts ring the centre, with the San Felipe fortress guarding the harbour above.
- Walled old town
- San Felipe fortress
- Plaza Santo Domingo
- Day9
Panama Canal Transit
- Day10
At Sea
- Day11
At Sea
- Day12

Manta
Arrive 07:00 · Depart 16:00
- Day13

Guayaquil
Arrive 08:00 · Depart 16:00
- Day14
At Sea
- Day15

Callao
Arrive 14:00
Peru's chief seaport, on the Pacific beside Lima. Ships dock here for the colonial centre and museums of the capital, the cliff-top Miraflores district above the ocean, and onward journeys toward Machu Picchu and the Andean highlands.
- Gateway to Lima
- Miraflores
- Historic centre
- Day16

Callao
Depart 20:00
Peru's chief seaport, on the Pacific beside Lima. Ships dock here for the colonial centre and museums of the capital, the cliff-top Miraflores district above the ocean, and onward journeys toward Machu Picchu and the Andean highlands.
- Gateway to Lima
- Miraflores
- Historic centre
- Day17

Pisco
Arrive 07:00 · Depart 16:00
- Day18
At Sea
- Day19
At Sea
- Day20

Coquimbo
Arrive 09:00 · Depart 17:00
- Day21

San Antonio
Arrive 09:00 · Depart 18:00
- Day22
At Sea
- Day23

Puerto Montt
Arrive 08:00 · Depart 16:00
A port city in Chile's Lake District, set on the Reloncaví Sound where the central valley meets the fjords of Patagonia. Snow-capped volcanoes ring the bay, and the town is a launch point for trips to lakes, the German-influenced settlement of Puerto Varas and Chiloé island.
- Osorno Volcano
- Puerto Varas
- Angelmó market
- Day24

Puerto Chacabuco
Arrive 10:00 · Depart 20:00
- Day25

Laguna San Rafael National Park
Arrive 07:00 · Depart 17:00
- Day26
Cruising the Chilean Fjords
- Day27
Cruising the Chilean Fjords
- Day28

Punta Arenas
Arrive 08:00 · Depart 18:00
A windswept city on the Strait of Magellan in Chilean Patagonia, one of the southernmost ports on earth. It serves as a gateway to Tierra del Fuego, Antarctic crossings and nearby penguin colonies, with a grand central plaza recalling the wool and shipping boom.
- Strait of Magellan
- Plaza de Armas
- Penguin colonies
- Day29
Sailing around Cape Horn
- Day30

Ushuaia
Arrive 08:00 · Depart 18:00
The world's southernmost city, on Argentina's Tierra del Fuego at the tip of South America. Backed by snowy peaks on the Beagle Channel, it is the chief departure port for Antarctica and a base for the Patagonian wilderness.
- Beagle Channel
- Tierra del Fuego park
- End of the world
- Day31
At Sea
- Day32

Port Stanley
Arrive 07:00 · Depart 16:00
The small capital of the Falkland Islands in the South Atlantic, a row of brightly painted houses and tin roofs along a sheltered harbour. Penguin colonies and windswept moorland surround the settlement, with Christ Church Cathedral and its whalebone arch at the waterfront.
- Penguin colonies
- Whalebone Arch
- Christ Church Cathedral
- Day33
At Sea
- Day34

Puerto Madryn
Arrive 08:00 · Depart 16:00
A Patagonian port on the Gulf of Nuevo in Argentine coastal Chubut, founded by Welsh settlers. It is the gateway to the Península Valdés nature reserve, where southern right whales, sea lions and penguins gather along the coast.
- Península Valdés
- Whale watching
- Welsh heritage
- Day35
At Sea
- Day36

Punta del Este
Arrive 11:00 · Depart 17:00
- Day37

Buenos Aires
Arrive 06:00 · Depart 18:00
Argentina's grand capital on the Río de la Plata, a city of wide boulevards and European-style architecture. The tango was born in its streets, with the colourful houses of La Boca and the cafés of San Telmo close to the waterfront.
- La Boca
- San Telmo
- Tango culture
Upcoming departures
- 19 Dec 2026
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
36-Night Americas Cruise from Miami, Florida FAQ
Which ports does this cruise visit?
This 36-night Americas cruise calls at Miami, Florida, Key West, Florida, At Sea, Willemstad, Oranjestad, Santa Marta, Cartagena, Panama Canal Transit, Manta, Guayaquil, Callao, Pisco, Coquimbo, San Antonio, Puerto Montt, Puerto Chacabuco, Laguna San Rafael National Park, Cruising the Chilean Fjords, Punta Arenas, Sailing around Cape Horn, Ushuaia, Port Stanley, Puerto Madryn, Punta del Este and Buenos Aires.
How many days are spent at sea?
13 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Miami, Florida and ends in Buenos Aires.
How long is this cruise?
36 nights aboard Oceania Insignia.
When does this itinerary sail?
Upcoming departures include 19 Dec 2026. A NestCruise advisor can confirm current availability.