

Cruise itinerary
33-Night South America Cruise from Buenos Aires
33 nights · South America · 19 ports of call
33-night South America cruise aboard Oceania Insignia, departing Buenos Aires and calling at Montevideo, Punta del Este, Rio Grande, Florianópolis, Itajai and Santos and 12 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Oceania Insignia
- Cruise line
- Oceania Cruises
- Duration
- 33 nights
- Region
- South America
- Departs
- Buenos Aires
- Returns
- Miami, Florida
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Oceania Insignia sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Buenos Aires
Depart 18:00
Argentina's grand capital on the Río de la Plata, a city of wide boulevards and European-style architecture. The tango was born in its streets, with the colourful houses of La Boca and the cafés of San Telmo close to the waterfront.
- La Boca
- San Telmo
- Tango culture
- Day2

Montevideo
Arrive 08:00 · Depart 20:00
The capital of Uruguay, set on the north bank of the broad Río de la Plata. Its old town keeps colonial plazas and a long riverside promenade, the Rambla, in a relaxed South American port city known for grilled meat and mate.
- Ciudad Vieja
- The Rambla
- Plaza Independencia
- Day3

Punta del Este
Arrive 07:00 · Depart 16:00
- Day4

Rio Grande
Arrive 11:00 · Depart 20:00
- Day5At sea
- Day6
Florianópolis
Arrive 07:00 · Depart 19:00
- Day7

Itajai
Arrive 07:00 · Depart 17:00
- Day8

Santos
Arrive 09:00 · Depart 18:00
Brazil's busiest port, on the coast of São Paulo state and the main gateway to that vast city. Its waterfront sits below green coastal hills, with historic coffee-trade buildings, an aquarium and long urban beaches backed by a seafront garden.
- Coffee Museum
- Santos beach gardens
- Pelé Museum
- Day9
Paraty, Rio De Janeiro
Arrive 08:00 · Depart 18:00
- Day10

Ilha Grande
Arrive 08:00 · Depart 18:00
- Day11

Buzios
Arrive 08:00 · Depart 18:00
A chic beach resort on a rocky peninsula east of Rio de Janeiro, Brazil, once a fishing village made famous by Brigitte Bardot. Some two dozen beaches ring the headland, with a cobbled centre, a sailing harbour and the Orla Bardot promenade.
- Geribá Beach
- Rua das Pedras
- Orla Bardot
- Day12

Rio de Janeiro
Arrive 08:00 · Depart 16:00
Brazil's great coastal city, set between forested mountains and the Atlantic. The Christ the Redeemer statue looks down from Corcovado, Sugarloaf rises over the harbour mouth, and the sands of Copacabana and Ipanema run along the city's southern edge.
- Christ the Redeemer
- Sugarloaf Mountain
- Copacabana Beach
- Day13At sea
- Day14At sea
- Day15At sea
- Day16At sea
- Day17At sea
- Day18At sea
- Day19At sea
- Day20

Santarém
Arrive 14:00 · Depart 20:00
- Day21
Boca da Valeria
Arrive 08:00 · Depart 15:00
- Day22

Manaus
Arrive 09:00 · Depart 18:00
The largest city of the Brazilian Amazon, rising deep in the rainforest where the dark Rio Negro meets the sandy Solimões. Grown rich on the rubber boom, it is known for its opulent opera house and as the gateway to jungle lodges and the Meeting of the Waters.
- Amazonas Opera House
- Meeting of the Waters
- Adolpho Lisboa Market
- Day23At sea
- Day24

Parintins
Arrive 12:00 · Depart 18:00
- Day25

Santarém
Arrive 07:00 · Depart 12:00
- Day26At sea
- Day27At sea
- Day28At sea
- Day29

Bridgetown
Arrive 07:00 · Depart 15:00
The capital of Barbados on the island's southwest coast, a long-standing Caribbean cruise port. Its colonial centre and Garrison Savannah are UNESCO-listed, with the white sand of Carlisle Bay and turtle-filled waters close to the harbour.
- Carlisle Bay
- Garrison Savannah
- Rum distilleries
- Day30

Antigua
Arrive 11:00 · Depart 18:00
- Day31

Saint Thomas
Arrive 07:00 · Depart 17:00
An island in the U.S. Virgin Islands known for its deep harbour at Charlotte Amalie and its red-roofed hillsides. It offers duty-free shopping along the waterfront, the beach at Magens Bay, and a short ferry hop to quieter St. John.
- Magens Bay
- Charlotte Amalie
- Ferry to St. John
- Day32At sea
- Day33At sea
- Day34

Miami, Florida
Arrive 08:00
The cruise capital of the world — Miami sends more ships to sea than any port on earth. Most sailings board mid-afternoon, leaving the morning for South Beach, Little Havana or the Wynwood murals before you cast off.
- South Beach
- Little Havana
- Wynwood murals
Upcoming departures
- 7 Mar 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
33-Night South America Cruise from Buenos Aires FAQ
Which ports does this cruise visit?
This 33-night South America cruise calls at Buenos Aires, Montevideo, Punta del Este, Rio Grande, Florianópolis, Itajai, Santos, Paraty, Rio De Janeiro, Ilha Grande, Buzios, Rio de Janeiro, Santarém, Boca da Valeria, Manaus, Parintins, Bridgetown, Antigua, Saint Thomas and Miami, Florida.
How many days are spent at sea?
14 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Buenos Aires and ends in Miami, Florida.
How long is this cruise?
33 nights aboard Oceania Insignia.
When does this itinerary sail?
Upcoming departures include 7 Mar 2027. A NestCruise advisor can confirm current availability.