

Cruise itinerary
22-Night Mediterranean Cruise from Barcelona
22 nights · Mediterranean · 15 ports of call
22-night Mediterranean cruise aboard Oceania Insignia, departing Barcelona and calling at Palma de Mallorca, Alicante, Cartagena, Málaga, Seville and Portimão and 8 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Oceania Insignia
- Cruise line
- Oceania Cruises
- Duration
- 22 nights
- Region
- Mediterranean · Transatlantic
- Departs
- Barcelona
- Returns
- Miami, Florida
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Oceania Insignia sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Barcelona
Arrive 07:00 · Depart 17:00
Catalonia's seafront capital and one of the Mediterranean's busiest cruise homeports. Gaudí's Sagrada Família and Park Güell crown the city, while the tree-lined Ramblas and the Gothic Quarter's medieval lanes lie a short ride from the terminal.
- Sagrada Família
- La Rambla
- Gothic Quarter
- Day2

Palma de Mallorca
Arrive 08:00 · Depart 18:00
The capital of Mallorca in Spain's Balearic Islands, set around a wide bay. Its enormous seafront cathedral, La Seu, rises above the old town's narrow lanes, with a hilltop castle, marina and nearby coves a short way from the cruise terminal.
- La Seu cathedral
- Bellver Castle
- Old town
- Day3

Alicante
Arrive 08:00 · Depart 18:00
A sun-warmed port on Spain's Costa Blanca, set below the Santa Bárbara castle on its rocky headland. The palm-lined Explanada promenade leads to a long city beach, with the old Barrio Santa Cruz climbing the hill in white houses.
- Santa Bárbara Castle
- Explanada promenade
- Postiguet Beach
- Day4

Cartagena
Arrive 07:00 · Depart 17:00
A naval port in the Murcia region of southeastern Spain, sheltered by hills around a deep harbour. Layers of Roman, Carthaginian and modern history meet here, including a restored Roman theatre uncovered in the city centre.
- Roman theatre
- Naval harbour
- Concepción Castle
- Day5

Málaga
Arrive 08:00 · Depart 19:00
A port city on Spain's Costa del Sol and the birthplace of Picasso. Cruise ships berth near the centre, where a hilltop Moorish fortress, the cathedral and the Picasso Museum sit close to broad city beaches and fried-fish chiringuitos.
- Alcazaba fortress
- Picasso Museum
- Costa del Sol beaches
- Day6

Seville
Arrive 07:00 · Depart 19:00
Andalusia's historic capital, reached by river barge up the Guadalquivir in southern Spain. The vast Gothic cathedral, the Moorish Alcázar palace and the dancing of flamenco define a city once enriched by trade with the New World.
- Seville Cathedral
- Royal Alcázar
- Flamenco
- Day7

Portimão
Arrive 07:00 · Depart 17:00
A port town on the Algarve coast of southern Portugal, set at the mouth of the Arade River. It is known for grilled sardines and the golden cliffs and caves of nearby Praia da Rocha, one of the region's longest beaches.
- Praia da Rocha
- Grilled sardines
- Arade River
- Day8

Lisbon
Arrive 07:00 · Depart 17:00
Portugal's hilly capital, spread across seven hills above the Tagus estuary. Yellow trams climb to the Alfama's tangled lanes and the Castle of São Jorge, while Belém's monastery and pastéis de nata anchor the riverside to the west.
- Alfama district
- Belém Tower
- Tram 28
- Day9
At Sea
- Day10

Arrecife, Lanzarote
Arrive 10:00 · Depart 18:00
The port and capital of Lanzarote in Spain's Canary Islands, a low-rise town of white houses on a volcanic Atlantic island. Inland lie the lava fields of Timanfaya National Park and the cave and cactus works of the artist César Manrique.
- Timanfaya National Park
- Jameos del Agua
- Charco de San Ginés
- Day11

Las Palmas de Gran Canaria
Arrive 07:00 · Depart 17:00
The largest city of the Canary Islands, on Gran Canaria off the African coast. A long city beach curves beside the port, and the historic Vegueta quarter holds the cathedral and the house where Columbus is said to have stayed.
- Las Canteras Beach
- Vegueta quarter
- Columbus House
- Day12

Santa Cruz de La Palma
Arrive 07:00 · Depart 17:00
The capital of the Canary island of La Palma, built around a sheltered harbour on the Atlantic. Its old town keeps colourful balconied houses and cobbled streets, while the island beyond rises to volcanic ridges and the observatories of the Roque de los Muchachos.
- Old town balconies
- Plaza de España
- Volcanic ridges
- Day13
At Sea
- Day14
At Sea
- Day15
At Sea
- Day16
At Sea
- Day17
At Sea
- Day18
At Sea
- Day19

San Juan (Puerto Rico)
Arrive 11:00
The capital of Puerto Rico and a major Caribbean homeport. Old San Juan's pastel colonial streets sit behind the massive El Morro and San Cristóbal forts, with rum distilleries and the beaches of Condado close to the cruise piers.
- Old San Juan
- El Morro fort
- Condado beaches
- Day20

San Juan (Puerto Rico)
Depart 11:00
The capital of Puerto Rico and a major Caribbean homeport. Old San Juan's pastel colonial streets sit behind the massive El Morro and San Cristóbal forts, with rum distilleries and the beaches of Condado close to the cruise piers.
- Old San Juan
- El Morro fort
- Condado beaches
- Day21
At Sea
- Day22

Nassau
Arrive 11:00 · Depart 17:00
The capital of the Bahamas on New Providence Island, one of the most-visited cruise ports anywhere. Pastel colonial buildings and the Queen's Staircase sit near the harbour, with the sands of Cable Beach and the Atlantis resort just across the water.
- Cable Beach
- Atlantis resort
- Queen's Staircase
- Day23

Miami, Florida
Arrive 07:00 · Depart 17:00
The cruise capital of the world — Miami sends more ships to sea than any port on earth. Most sailings board mid-afternoon, leaving the morning for South Beach, Little Havana or the Wynwood murals before you cast off.
- South Beach
- Little Havana
- Wynwood murals
Upcoming departures
- 2 Nov 2026
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
22-Night Mediterranean Cruise from Barcelona FAQ
Which ports does this cruise visit?
This 22-night Mediterranean cruise calls at Barcelona, Palma de Mallorca, Alicante, Cartagena, Málaga, Seville, Portimão, Lisbon, At Sea, Arrecife, Lanzarote, Las Palmas de Gran Canaria, Santa Cruz de La Palma, San Juan (Puerto Rico), Nassau and Miami, Florida.
How many days are spent at sea?
8 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Barcelona and ends in Miami, Florida.
How long is this cruise?
22 nights aboard Oceania Insignia.
When does this itinerary sail?
Upcoming departures include 2 Nov 2026. A NestCruise advisor can confirm current availability.