Cruise itinerary
21-Night Americas Cruise from Rio de Janeiro
21 nights · Americas · 12 ports of call
21-night Americas cruise aboard Oceania Insignia, departing Rio de Janeiro and calling at At Sea, Cruising Amazon River, Alter do Chão, Boca de Valeria, Manaus and Parintins and 5 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Oceania Insignia
- Cruise line
- Oceania Cruises
- Duration
- 21 nights
- Region
- Americas · South America
- Departs
- Rio de Janeiro
- Returns
- Miami, Florida
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Oceania Insignia sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1
Rio de Janeiro
Depart 16:00
Brazil's great coastal city, set between forested mountains and the Atlantic. The Christ the Redeemer statue looks down from Corcovado, Sugarloaf rises over the harbour mouth, and the sands of Copacabana and Ipanema run along the city's southern edge.
- Christ the Redeemer
- Sugarloaf Mountain
- Copacabana Beach
- Day2
At Sea
- Day3
At Sea
- Day4
At Sea
- Day5
At Sea
- Day6
At Sea
- Day7
Cruising Amazon River
- Day8
Alter do Chão
Arrive 14:00 · Depart 20:00
- Day9
Boca de Valeria
Arrive 08:00 · Depart 15:00
- Day10
Manaus
Arrive 09:00
The largest city of the Brazilian Amazon, rising deep in the rainforest where the dark Rio Negro meets the sandy Solimões. Grown rich on the rubber boom, it is known for its opulent opera house and as the gateway to jungle lodges and the Meeting of the Waters.
- Amazonas Opera House
- Meeting of the Waters
- Adolpho Lisboa Market
- Day11
Manaus
Depart 18:00
The largest city of the Brazilian Amazon, rising deep in the rainforest where the dark Rio Negro meets the sandy Solimões. Grown rich on the rubber boom, it is known for its opulent opera house and as the gateway to jungle lodges and the Meeting of the Waters.
- Amazonas Opera House
- Meeting of the Waters
- Adolpho Lisboa Market
- Day12
Parintins
Arrive 12:00 · Depart 18:00
- Day13
Santarém
Arrive 07:00 · Depart 12:00
- Day14
Cruising Amazon River
- Day15
At Sea
- Day16
At Sea
- Day17
Bridgetown
Arrive 07:00 · Depart 15:00
The capital of Barbados on the island's southwest coast, a long-standing Caribbean cruise port. Its colonial centre and Garrison Savannah are UNESCO-listed, with the white sand of Carlisle Bay and turtle-filled waters close to the harbour.
- Carlisle Bay
- Garrison Savannah
- Rum distilleries
- Day18
Saint John's
Arrive 11:00 · Depart 18:00
The capital of Antigua, set around a deep natural harbour in the eastern Caribbean. The island is known for its many sandy beaches and for Nelson's Dockyard, a restored Georgian naval base on the south coast that is now a World Heritage site.
- Nelson's Dockyard
- Dickenson Bay
- Shirley Heights
- Day19
Charlotte Amalie
Arrive 07:00 · Depart 17:00
St. Thomas's harbour town in the U.S. Virgin Islands — a deep, sheltered bay ringed by red-roofed hills. Known for duty-free shopping along Main Street and the easy hop to Magens Bay or a ferry across to quieter St. John.
- Magens Bay
- Main Street shopping
- ferry to St. John
- Day20
At Sea
- Day21
At Sea
- Day22
Miami, Florida
Arrive 07:00 · Depart 18:00
The cruise capital of the world — Miami sends more ships to sea than any port on earth. Most sailings board mid-afternoon, leaving the morning for South Beach, Little Havana or the Wynwood murals before you cast off.
- South Beach
- Little Havana
- Wynwood murals
Upcoming departures
- 19 Mar 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
21-Night Americas Cruise from Rio de Janeiro FAQ
Which ports does this cruise visit?
This 21-night Americas cruise calls at Rio de Janeiro, At Sea, Cruising Amazon River, Alter do Chão, Boca de Valeria, Manaus, Parintins, Santarém, Bridgetown, Saint John's, Charlotte Amalie and Miami, Florida.
How many days are spent at sea?
11 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Rio de Janeiro and ends in Miami, Florida.
How long is this cruise?
21 nights aboard Oceania Insignia.
When does this itinerary sail?
Upcoming departures include 19 Mar 2027. A NestCruise advisor can confirm current availability.