

Cruise itinerary
15-Night Americas Cruise from Miami, Florida
15 nights · Americas · 11 ports of call
15-night Americas cruise aboard Oceania Insignia, departing Miami, Florida and calling at Key West, Florida, At Sea, Willemstad, Oranjestad, Santa Marta and Cartagena and 4 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Oceania Insignia
- Cruise line
- Oceania Cruises
- Duration
- 15 nights
- Region
- Americas · South America
- Departs
- Miami, Florida
- Returns
- Callao
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Oceania Insignia sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Miami, Florida
Arrive 07:00 · Depart 17:00
The cruise capital of the world — Miami sends more ships to sea than any port on earth. Most sailings board mid-afternoon, leaving the morning for South Beach, Little Havana or the Wynwood murals before you cast off.
- South Beach
- Little Havana
- Wynwood murals
- Day2

Key West, Florida
Arrive 07:00 · Depart 13:00
The southernmost city in the continental United States, an island town at the end of the Florida Keys. Pastel conch houses line Duval Street, Ernest Hemingway's home is a landmark, and crowds gather at Mallory Square for the nightly sunset.
- Duval Street
- Hemingway House
- Mallory Square sunset
- Day3
At Sea
- Day4
At Sea
- Day5

Willemstad
Arrive 11:00 · Depart 18:00
The capital of Curaçao in the southern Caribbean, with a UNESCO-listed centre of Dutch colonial architecture. Willemstad is known for the candy-coloured waterfront of Handelskade, the swinging Queen Emma pontoon bridge, and its floating market.
- Handelskade façades
- Queen Emma Bridge
- Floating Market
- Day6

Oranjestad
Arrive 07:00 · Depart 16:00
The capital of Aruba, set on the island's leeward south coast in the southern Caribbean. Oranjestad is known for its Dutch colonial façades along Wilhelminastraat, a free streetcar through downtown, and white-sand beaches like Eagle and Palm just north.
- Eagle Beach
- Palm Beach
- Dutch colonial centre
- Day7

Santa Marta
Arrive 09:00 · Depart 18:00
- Day8

Cartagena
Arrive 07:00 · Depart 13:30
A walled colonial city on Colombia's Caribbean coast, its old town a maze of pastel houses, balconies and shaded plazas. Massive stone ramparts ring the centre, with the San Felipe fortress guarding the harbour above.
- Walled old town
- San Felipe fortress
- Plaza Santo Domingo
- Day9
Panama Canal Transit
- Day10
At Sea
- Day11
At Sea
- Day12

Manta
Arrive 07:00 · Depart 16:00
- Day13

Guayaquil
Arrive 08:00 · Depart 16:00
- Day14
At Sea
- Day15

Callao
Arrive 14:00
Peru's chief seaport, on the Pacific beside Lima. Ships dock here for the colonial centre and museums of the capital, the cliff-top Miraflores district above the ocean, and onward journeys toward Machu Picchu and the Andean highlands.
- Gateway to Lima
- Miraflores
- Historic centre
- Day16

Callao
Depart 20:00
Peru's chief seaport, on the Pacific beside Lima. Ships dock here for the colonial centre and museums of the capital, the cliff-top Miraflores district above the ocean, and onward journeys toward Machu Picchu and the Andean highlands.
- Gateway to Lima
- Miraflores
- Historic centre
Upcoming departures
- 19 Dec 2026
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
15-Night Americas Cruise from Miami, Florida FAQ
Which ports does this cruise visit?
This 15-night Americas cruise calls at Miami, Florida, Key West, Florida, At Sea, Willemstad, Oranjestad, Santa Marta, Cartagena, Panama Canal Transit, Manta, Guayaquil and Callao.
How many days are spent at sea?
5 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Miami, Florida and ends in Callao.
How long is this cruise?
15 nights aboard Oceania Insignia.
When does this itinerary sail?
Upcoming departures include 19 Dec 2026. A NestCruise advisor can confirm current availability.