

Cruise itinerary
8-Night Mediterranean Cruise from Civitavecchia
8 nights · Mediterranean · 8 ports of call
8-night Mediterranean cruise aboard Crystal Serenity, departing Civitavecchia and calling at Salerno, Siracusa, Sicily, Valletta, Soúda, Crete, Nafplio and Syros and 1 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Crystal Serenity
- Cruise line
- Crystal
- Duration
- 8 nights
- Region
- Mediterranean
- Departs
- Civitavecchia
- Returns
- Piraeus
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Crystal Serenity sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Civitavecchia
Depart 19:00
The deep-water port serving Rome, roughly 80 kilometres up the coast. Ships dock here for shore excursions to the Colosseum, the Vatican and the Roman Forum, while the town itself keeps a working harbour and a Michelangelo-designed fortress.
- Gateway to Rome
- Fort Michelangelo
- Vatican excursions
- Day2

Salerno
Arrive 08:00 · Depart 18:00
An Italian port at the head of its own gulf, just south of the Amalfi Coast. Its long seafront and walkable medieval centre make it a quieter base for reaching Pompeii, Paestum's Greek temples and the cliffside towns of Amalfi and Positano.
- Amalfi Coast gateway
- Paestum temples
- Seafront promenade
- Day3
Siracusa, Sicily
Arrive 09:00 · Depart 19:00
- Day4

Valletta
Arrive 08:00 · Depart 19:00
Malta's fortified harbour capital, built by the Knights of St. John on a peninsula between two deep ports. Honey-coloured limestone defines St. John's Co-Cathedral, the Grand Master's Palace and the bastions overlooking the Grand Harbour.
- Grand Harbour
- St. John's Co-Cathedral
- Upper Barrakka Gardens
- Day5At sea
- Day6

Soúda, Crete
Arrive 07:00 · Depart 17:00
The port of Chania on the northwest coast of Crete, set beside Souda Bay, one of the Mediterranean's deepest natural harbours. It opens onto the old Venetian quarter of Chania, with its lighthouse, harbour-front, and lanes of the former Turkish town.
- Chania old town
- Venetian lighthouse
- Souda Bay
- Day7
Nafplio
Arrive 08:00 · Depart 18:00
- Day8

Syros
Arrive 08:00 · Depart 18:00
- Day9

Piraeus
Arrive 07:00
The ancient harbour of Athens and Greece's principal cruise port. Ferries fan out to the Aegean islands from its quays, while the Acropolis, the Plaka district and the National Archaeological Museum sit a short metro ride inland.
- Gateway to Athens
- Acropolis
- Aegean ferries
Upcoming departures
- 13 May 2028
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
8-Night Mediterranean Cruise from Civitavecchia FAQ
Which ports does this cruise visit?
This 8-night Mediterranean cruise calls at Civitavecchia, Salerno, Siracusa, Sicily, Valletta, Soúda, Crete, Nafplio, Syros and Piraeus.
How many days are spent at sea?
1 day is spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Civitavecchia and ends in Piraeus.
How long is this cruise?
8 nights aboard Crystal Serenity.
When does this itinerary sail?
Upcoming departures include 13 May 2028. A NestCruise advisor can confirm current availability.