

Cruise itinerary
28-Night Americas Cruise from Fort Lauderdale, Florida
28 nights · Americas · 20 ports of call
28-night Americas cruise aboard Crystal Serenity, departing Fort Lauderdale, Florida and calling at Nassau, At Sea, Samaná, San Juan (Puerto Rico), Great Harbour, Jost Van Dyke and Oranjestad and 13 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Crystal Serenity
- Cruise line
- Crystal
- Duration
- 28 nights
- Region
- Americas · South America
- Departs
- Fort Lauderdale, Florida
- Returns
- San Diego, California
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Crystal Serenity sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Fort Lauderdale, Florida
A South Florida port often called the yachting capital, fringed by canals and the long sands of Fort Lauderdale Beach. Port Everglades is among the world's busiest cruise gateways, with Las Olas Boulevard's shops and cafés minutes from the piers.
- Port Everglades
- Las Olas Boulevard
- Fort Lauderdale Beach
- Day2

Nassau
The capital of the Bahamas on New Providence Island, one of the most-visited cruise ports anywhere. Pastel colonial buildings and the Queen's Staircase sit near the harbour, with the sands of Cable Beach and the Atlantis resort just across the water.
- Cable Beach
- Atlantis resort
- Queen's Staircase
- Day3
At Sea
- Day4

Samaná
- Day5

San Juan (Puerto Rico)
The capital of Puerto Rico and a major Caribbean homeport. Old San Juan's pastel colonial streets sit behind the massive El Morro and San Cristóbal forts, with rum distilleries and the beaches of Condado close to the cruise piers.
- Old San Juan
- El Morro fort
- Condado beaches
- Day6

Great Harbour, Jost Van Dyke
The main anchorage of Jost Van Dyke, smallest of the British Virgin Islands' main islands, in the Caribbean. A laid-back yachting stop, its sheltered bay is fringed by sand and beach bars, with the natural rock pools of the Bubbly Pool a short walk away.
- Bubbly Pool
- White Bay
- beach bars
- Day7
At Sea
- Day8

Oranjestad
The capital of Aruba, set on the island's leeward south coast in the southern Caribbean. Oranjestad is known for its Dutch colonial façades along Wilhelminastraat, a free streetcar through downtown, and white-sand beaches like Eagle and Palm just north.
- Eagle Beach
- Palm Beach
- Dutch colonial centre
- Day9

Cartagena
A walled colonial city on Colombia's Caribbean coast, its old town a maze of pastel houses, balconies and shaded plazas. Massive stone ramparts ring the centre, with the San Felipe fortress guarding the harbour above.
- Walled old town
- San Felipe fortress
- Plaza Santo Domingo
- Day10

Cartagena
A walled colonial city on Colombia's Caribbean coast, its old town a maze of pastel houses, balconies and shaded plazas. Massive stone ramparts ring the centre, with the San Felipe fortress guarding the harbour above.
- Walled old town
- San Felipe fortress
- Plaza Santo Domingo
- Day11
At Sea
- Day12

Willemstad
The capital of Curaçao in the southern Caribbean, with a UNESCO-listed centre of Dutch colonial architecture. Willemstad is known for the candy-coloured waterfront of Handelskade, the swinging Queen Emma pontoon bridge, and its floating market.
- Handelskade façades
- Queen Emma Bridge
- Floating Market
- Day13

Kralendijk
The capital of Bonaire, a Dutch-Caribbean island known above all for diving and snorkelling along its protected fringing reef. The small waterfront town keeps pastel Dutch-colonial facades, with salt pans and flamingo flats lying to the south.
- Bonaire reef diving
- Salt pans
- Flamingo flats
- Day14

Oranjestad
The capital of Aruba, set on the island's leeward south coast in the southern Caribbean. Oranjestad is known for its Dutch colonial façades along Wilhelminastraat, a free streetcar through downtown, and white-sand beaches like Eagle and Palm just north.
- Eagle Beach
- Palm Beach
- Dutch colonial centre
- Day15

Santa Marta
- Day16
At Sea
- Day17

Fuerte Amador
A causeway-linked island port on the Pacific side of the Panama Canal, just off Panama City. It serves as the gateway to the canal's locks and rainforest, with the Amador Causeway reaching toward the capital's skyline and old quarter.
- Panama Canal
- Amador Causeway
- Casco Viejo
Panama Canal Transit
- Day18

Fuerte Amador
A causeway-linked island port on the Pacific side of the Panama Canal, just off Panama City. It serves as the gateway to the canal's locks and rainforest, with the Amador Causeway reaching toward the capital's skyline and old quarter.
- Panama Canal
- Amador Causeway
- Casco Viejo
- Day19
At Sea
- Day20

Puntarenas
A Pacific port city on a narrow sandy spit on Costa Rica's central coast. It serves chiefly as a gateway inland to rainforests and volcanoes, with a long beachfront promenade and boats out to the Gulf of Nicoya's islands.
- Gulf of Nicoya
- Beachfront paseo
- Rainforest gateway
- Day21

Playa Flamingo
- Day22

Acajutla
- Day23
At Sea
- Day24
Zihuatanejo
- Day25

Manzanillo, Mexico
- Day26

Puerto Vallarta
A resort city on Mexico's Pacific coast, set where the Sierra Madre meets Banderas Bay. Its cobbled Zona Romántica and the seaside Malecón promenade anchor an old town of churches and galleries, with whale-watching in the bay through the winter months.
- The Malecón
- Zona Romántica
- Banderas Bay
- Day27
At Sea
- Day28
At Sea
- Day29

San Diego, California
A relaxed harbour city in southern California, known for its mild climate and broad natural bay. The waterfront holds the historic Gaslamp Quarter and maritime museums, with the green expanse of Balboa Park and its zoo just inland.
- Balboa Park
- Gaslamp Quarter
- San Diego Zoo
Upcoming departures
- 23 Nov 2026
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
28-Night Americas Cruise from Fort Lauderdale, Florida FAQ
Which ports does this cruise visit?
This 28-night Americas cruise calls at Fort Lauderdale, Florida, Nassau, At Sea, Samaná, San Juan (Puerto Rico), Great Harbour, Jost Van Dyke, Oranjestad, Cartagena, Willemstad, Kralendijk, Santa Marta, Fuerte Amador, Panama Canal Transit, Puntarenas, Playa Flamingo, Acajutla, Zihuatanejo, Manzanillo, Mexico, Puerto Vallarta and San Diego, California.
How many days are spent at sea?
8 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Fort Lauderdale, Florida and ends in San Diego, California.
How long is this cruise?
28 nights aboard Crystal Serenity.
When does this itinerary sail?
Upcoming departures include 23 Nov 2026. A NestCruise advisor can confirm current availability.