

Cruise itinerary
25-Night Americas Cruise from Fort Lauderdale, Florida
25 nights · Americas · 15 ports of call
25-night Americas cruise aboard Crystal Serenity, departing Fort Lauderdale, Florida and calling at At Sea, Road Town, Tortola, Pointe-à-Pitre, Castries, Scarborough and Santarém and 8 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Crystal Serenity
- Cruise line
- Crystal
- Duration
- 25 nights
- Region
- Americas · South America
- Departs
- Fort Lauderdale, Florida
- Returns
- Fort Lauderdale, Florida
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Crystal Serenity sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Fort Lauderdale, Florida
A South Florida port often called the yachting capital, fringed by canals and the long sands of Fort Lauderdale Beach. Port Everglades is among the world's busiest cruise gateways, with Las Olas Boulevard's shops and cafés minutes from the piers.
- Port Everglades
- Las Olas Boulevard
- Fort Lauderdale Beach
- Day2
At Sea
- Day3
At Sea
- Day4

Road Town, Tortola
The capital of Tortola in the British Virgin Islands, set on a harbour ringed by green hills. It is the main yachting base of the archipelago, with sheltered beaches, a small botanic garden, and ferries out to the surrounding cays.
- Cane Garden Bay
- Botanic Gardens
- Yacht harbour
- Day5

Pointe-à-Pitre
The main town of Guadeloupe, a French overseas region in the eastern Caribbean shaped like a butterfly. It sits between the two wings of the island, with a covered spice market, Creole cooking and the volcano of La Soufrière to the south.
- Spice market
- La Soufrière
- Memorial ACTe
- Day6

Castries
The capital of St. Lucia, tucked into a sheltered harbour on the island's northwest coast. Beyond the market town rise the rainforested interior and the iconic twin Piton peaks further south along the volcanic coastline.
- The Pitons
- Central market
- Pigeon Island
- Day7

Scarborough
- Day8
At Sea
- Day9
At Sea
- Day10
At Sea
- Day11

Santarém
- Day12
Boca da Valeria
- Day13

Manaus
The largest city of the Brazilian Amazon, rising deep in the rainforest where the dark Rio Negro meets the sandy Solimões. Grown rich on the rubber boom, it is known for its opulent opera house and as the gateway to jungle lodges and the Meeting of the Waters.
- Amazonas Opera House
- Meeting of the Waters
- Adolpho Lisboa Market
- Day14

Manaus
The largest city of the Brazilian Amazon, rising deep in the rainforest where the dark Rio Negro meets the sandy Solimões. Grown rich on the rubber boom, it is known for its opulent opera house and as the gateway to jungle lodges and the Meeting of the Waters.
- Amazonas Opera House
- Meeting of the Waters
- Adolpho Lisboa Market
- Day15

Parintins
- Day16

Alter do Chão
- Day17
At Sea
- Day18
At Sea
- Day19
Iles du Salut
- Day20
At Sea
- Day21

Bridgetown
The capital of Barbados on the island's southwest coast, a long-standing Caribbean cruise port. Its colonial centre and Garrison Savannah are UNESCO-listed, with the white sand of Carlisle Bay and turtle-filled waters close to the harbour.
- Carlisle Bay
- Garrison Savannah
- Rum distilleries
- Day22

Roseau
The capital of Dominica, a green volcanic island in the eastern Caribbean known as the Nature Isle. The town sits below forested peaks, with the botanic gardens, sulphur springs and the trail to Trafalgar Falls a short drive inland.
- Trafalgar Falls
- Botanic Gardens
- Boiling Lake
- Day23

Gustavia
The harbour capital of St. Barthélemy, a chic French island in the Caribbean. Yachts crowd the small port below red-roofed hills, with designer boutiques along the quay and quiet coves and beaches scattered around the rugged coast.
- Shell Beach
- Designer boutiques
- Gustavia harbour
- Day24
At Sea
- Day25
At Sea
- Day26

Fort Lauderdale, Florida
A South Florida port often called the yachting capital, fringed by canals and the long sands of Fort Lauderdale Beach. Port Everglades is among the world's busiest cruise gateways, with Las Olas Boulevard's shops and cafés minutes from the piers.
- Port Everglades
- Las Olas Boulevard
- Fort Lauderdale Beach
Upcoming departures
- 18 Jan 2028
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
25-Night Americas Cruise from Fort Lauderdale, Florida FAQ
Which ports does this cruise visit?
This 25-night Americas cruise calls at Fort Lauderdale, Florida, At Sea, Road Town, Tortola, Pointe-à-Pitre, Castries, Scarborough, Santarém, Boca da Valeria, Manaus, Parintins, Alter do Chão, Iles du Salut, Bridgetown, Roseau and Gustavia.
How many days are spent at sea?
10 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It is a round-trip sailing from Fort Lauderdale, Florida.
How long is this cruise?
25 nights aboard Crystal Serenity.
When does this itinerary sail?
Upcoming departures include 18 Jan 2028. A NestCruise advisor can confirm current availability.