

Cruise itinerary
24-Night Europe Cruise from Lisbon
24 nights · Europe · 22 ports of call
24-night Europe cruise aboard Crystal Serenity, departing Lisbon and calling at Portimão, Tangier, Melilla, At Sea, Tunis and Cagliari and 15 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Crystal Serenity
- Cruise line
- Crystal
- Duration
- 24 nights
- Region
- Europe · Southern Europe · Mediterranean
- Departs
- Lisbon
- Returns
- Piraeus
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Crystal Serenity sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Lisbon
Portugal's hilly capital, spread across seven hills above the Tagus estuary. Yellow trams climb to the Alfama's tangled lanes and the Castle of São Jorge, while Belém's monastery and pastéis de nata anchor the riverside to the west.
- Alfama district
- Belém Tower
- Tram 28
- Day2

Portimão
A port town on the Algarve coast of southern Portugal, set at the mouth of the Arade River. It is known for grilled sardines and the golden cliffs and caves of nearby Praia da Rocha, one of the region's longest beaches.
- Praia da Rocha
- Grilled sardines
- Arade River
- Day3

Tangier
A Moroccan port at the mouth of the Strait of Gibraltar, where the Atlantic meets the Mediterranean and Europe lies in view across the water. Its walled medina and kasbah climb above the harbour, long a meeting point of African, Arab and European worlds.
- The Medina
- Kasbah
- Strait of Gibraltar
- Day4

Melilla
- Day5
At Sea
- Day6

Tunis
The capital of Tunisia, set on a lagoon near the North African coast. Its walled medina is a UNESCO maze of souks and mosques, while the ruins of ancient Carthage and the blue-and-white village of Sidi Bou Said lie a short ride out.
- Medina souks
- Carthage ruins
- Sidi Bou Said
- Day7

Cagliari
The capital of Sardinia, an Italian port set across hills above the Gulf of the Angels. Its fortified Castello quarter looks down over the harbour, with a long city beach at Poetto and the Roman amphitheatre among its older landmarks.
- Castello quarter
- Poetto Beach
- Roman amphitheatre
- Day8

Ajaccio, Corsica
The capital of Corsica and Napoleon's birthplace, set on a sheltered gulf on the island's west coast. Ajaccio is known for its Bonaparte family house, the citadel and old town, and the rugged Sanguinaires islands off the harbour mouth.
- Maison Bonaparte
- Sanguinaires islands
- Ajaccio citadel
- Day9

Marseille
France's oldest city and biggest Mediterranean port, set around the old harbour of the Vieux-Port. The hilltop basilica of Notre-Dame de la Garde watches over the bay, with the Calanques inlets and bouillabaisse stalls a short way off.
- Vieux-Port
- Notre-Dame de la Garde
- Calanques
- Day10

Palamós
A fishing town and marina on Spain's Costa Brava, north of Barcelona in Catalonia. Its working harbour and old quarter back onto a curve of beach, while the rocky coves and pine-clad coastline of the region stretch in both directions from the port.
- Costa Brava coves
- Town beach
- Fishing harbour
- Day11

Barcelona
Catalonia's seafront capital and one of the Mediterranean's busiest cruise homeports. Gaudí's Sagrada Família and Park Güell crown the city, while the tree-lined Ramblas and the Gothic Quarter's medieval lanes lie a short ride from the terminal.
- Sagrada Família
- La Rambla
- Gothic Quarter
- Day12
At Sea
- Day13

Toulon
A major French naval port on the Mediterranean, set on a wide harbour beneath the heights of Mont Faron. Its old town and Provençal market lie behind the waterfront, and a cable car climbs the mountain for sweeping views over the roadstead.
- Mont Faron
- Provençal market
- Naval harbour
- Day14

Monte-Carlo
The seafront quarter of Monaco on the French Riviera, set on a rocky terrace above the Mediterranean. It is known for the belle-époque Casino, the Hôtel de Paris and the harbour that hosts the Monaco Grand Prix each spring.
- Casino de Monte-Carlo
- Port Hercule
- Grand Prix circuit
- Day15

Portofino
A small fishing village on the Italian Riviera, its pastel houses curved around a sheltered harbour on a wooded promontory in Liguria. Long a retreat for yachts and writers, it has a tiny piazzetta, hillside church and coastal paths toward Genoa.
- Piazzetta harbour
- Castello Brown
- San Fruttuoso
- Day16

Livorno
A Tuscan port on the Ligurian Sea and the gateway to Florence and Pisa. Ships dock here for excursions to Renaissance galleries and the Leaning Tower, while Livorno itself is known for its canal district and a seafood stew called cacciucco.
- Gateway to Florence
- Pisa excursions
- Venezia Nuova canals
- Day17

Livorno
A Tuscan port on the Ligurian Sea and the gateway to Florence and Pisa. Ships dock here for excursions to Renaissance galleries and the Leaning Tower, while Livorno itself is known for its canal district and a seafood stew called cacciucco.
- Gateway to Florence
- Pisa excursions
- Venezia Nuova canals
- Day18

Civitavecchia
The deep-water port serving Rome, roughly 80 kilometres up the coast. Ships dock here for shore excursions to the Colosseum, the Vatican and the Roman Forum, while the town itself keeps a working harbour and a Michelangelo-designed fortress.
- Gateway to Rome
- Fort Michelangelo
- Vatican excursions
- Day19

Naples
A southern Italian port on its namesake bay, in the shadow of Mount Vesuvius. Ships dock near the historic centre, the gateway to Pompeii, the cliffs of the Amalfi Coast and the island of Capri, in a city that claims to have invented pizza.
- Mount Vesuvius
- Pompeii
- Gateway to Capri
- Day20

Messina
A Sicilian port on the strait that separates the island from mainland Italy, framed by the Peloritani mountains. Its harbour clock tower performs an elaborate noon display, and the town is a common gateway to Taormina and the slopes of Mount Etna.
- Etna day trips
- Taormina gateway
- Astronomical clock
- Day21

Valletta
Malta's fortified harbour capital, built by the Knights of St. John on a peninsula between two deep ports. Honey-coloured limestone defines St. John's Co-Cathedral, the Grand Master's Palace and the bastions overlooking the Grand Harbour.
- Grand Harbour
- St. John's Co-Cathedral
- Upper Barrakka Gardens
- Day22
At Sea
- Day23

Soúda, Crete
The port of Chania on the northwest coast of Crete, set beside Souda Bay, one of the Mediterranean's deepest natural harbours. It opens onto the old Venetian quarter of Chania, with its lighthouse, harbour-front, and lanes of the former Turkish town.
- Chania old town
- Venetian lighthouse
- Souda Bay
- Day24

Kusadasi
A resort town on Turkey's Aegean coast that serves as the cruise gateway to ancient Ephesus, one of the best-preserved classical cities in the Mediterranean. Pigeon Island guards the harbour, and the marble Library of Celsus lies a short drive inland.
- Ephesus ruins
- Library of Celsus
- Pigeon Island
- Day25

Piraeus
The ancient harbour of Athens and Greece's principal cruise port. Ferries fan out to the Aegean islands from its quays, while the Acropolis, the Plaka district and the National Archaeological Museum sit a short metro ride inland.
- Gateway to Athens
- Acropolis
- Aegean ferries
Upcoming departures
- 29 Sep 2028
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
24-Night Europe Cruise from Lisbon FAQ
Which ports does this cruise visit?
This 24-night Europe cruise calls at Lisbon, Portimão, Tangier, Melilla, At Sea, Tunis, Cagliari, Ajaccio, Corsica, Marseille, Palamós, Barcelona, Toulon, Monte-Carlo, Portofino, Livorno, Civitavecchia, Naples, Messina, Valletta, Soúda, Crete, Kusadasi and Piraeus.
How many days are spent at sea?
3 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Lisbon and ends in Piraeus.
How long is this cruise?
24 nights aboard Crystal Serenity.
When does this itinerary sail?
Upcoming departures include 29 Sep 2028. A NestCruise advisor can confirm current availability.