

Cruise itinerary
25-Night Caribbean Cruise from Fort Lauderdale, Florida
25 nights · Caribbean · 13 ports of call
25-night Caribbean cruise aboard Crystal Serenity, departing Fort Lauderdale, Florida and calling at Tortola, Pointe-à-Pitre, Castries, Scarborough, Santarém and Boca da Valeria and 6 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Crystal Serenity
- Cruise line
- Crystal
- Duration
- 25 nights
- Region
- Caribbean
- Departs
- Fort Lauderdale, Florida
- Returns
- Fort Lauderdale, Florida
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Crystal Serenity sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Fort Lauderdale, Florida
Depart 18:00
A South Florida port often called the yachting capital, fringed by canals and the long sands of Fort Lauderdale Beach. Port Everglades is among the world's busiest cruise gateways, with Las Olas Boulevard's shops and cafés minutes from the piers.
- Port Everglades
- Las Olas Boulevard
- Fort Lauderdale Beach
- Day2At sea
- Day3At sea
- Day4

Tortola
Arrive 07:00 · Depart 17:00
The main island of the British Virgin Islands, where steep green hills drop to a yacht-filled harbour at Road Town. It is a noted sailing base in the Caribbean, with quiet bays such as Cane Garden and ferries out to neighbouring Virgin Gorda.
- Road Town
- Cane Garden Bay
- Sailing charters
- Day5

Pointe-à-Pitre
Arrive 09:00 · Depart 18:00
The main town of Guadeloupe, a French overseas region in the eastern Caribbean shaped like a butterfly. It sits between the two wings of the island, with a covered spice market, Creole cooking and the volcano of La Soufrière to the south.
- Spice market
- La Soufrière
- Memorial ACTe
- Day6

Castries
Arrive 07:00 · Depart 17:00
The capital of St. Lucia, tucked into a sheltered harbour on the island's northwest coast. Beyond the market town rise the rainforested interior and the iconic twin Piton peaks further south along the volcanic coastline.
- The Pitons
- Central market
- Pigeon Island
- Day7

Scarborough
Arrive 07:00 · Depart 17:00
- Day8At sea
- Day9At sea
- Day10At sea
- Day11

Santarém
Arrive 10:00 · Depart 19:00
- Day12
Boca da Valeria
Arrive 07:00 · Depart 15:00
- Day13

Manaus
Arrive 10:00 · Depart 16:00
The largest city of the Brazilian Amazon, rising deep in the rainforest where the dark Rio Negro meets the sandy Solimões. Grown rich on the rubber boom, it is known for its opulent opera house and as the gateway to jungle lodges and the Meeting of the Waters.
- Amazonas Opera House
- Meeting of the Waters
- Adolpho Lisboa Market
- Day14At sea
- Day15

Parintins
Arrive 10:00 · Depart 18:00
- Day16

Santarém
Arrive 09:00 · Depart 17:00
- Day17At sea
- Day18At sea
- Day19
Iles du Salut
Arrive 07:00 · Depart 15:00
- Day20At sea
- Day21

Bridgetown
Arrive 08:00 · Depart 17:00
The capital of Barbados on the island's southwest coast, a long-standing Caribbean cruise port. Its colonial centre and Garrison Savannah are UNESCO-listed, with the white sand of Carlisle Bay and turtle-filled waters close to the harbour.
- Carlisle Bay
- Garrison Savannah
- Rum distilleries
- Day22

Roseau
Arrive 08:00 · Depart 17:00
The capital of Dominica, a green volcanic island in the eastern Caribbean known as the Nature Isle. The town sits below forested peaks, with the botanic gardens, sulphur springs and the trail to Trafalgar Falls a short drive inland.
- Trafalgar Falls
- Botanic Gardens
- Boiling Lake
- Day23

Gustavia
Arrive 08:00 · Depart 17:00
The harbour capital of St. Barthélemy, a chic French island in the Caribbean. Yachts crowd the small port below red-roofed hills, with designer boutiques along the quay and quiet coves and beaches scattered around the rugged coast.
- Shell Beach
- Designer boutiques
- Gustavia harbour
- Day24At sea
- Day25At sea
- Day26

Fort Lauderdale, Florida
Arrive 07:00
A South Florida port often called the yachting capital, fringed by canals and the long sands of Fort Lauderdale Beach. Port Everglades is among the world's busiest cruise gateways, with Las Olas Boulevard's shops and cafés minutes from the piers.
- Port Everglades
- Las Olas Boulevard
- Fort Lauderdale Beach
Upcoming departures
- 18 Jan 2028
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
25-Night Caribbean Cruise from Fort Lauderdale, Florida FAQ
Which ports does this cruise visit?
This 25-night Caribbean cruise calls at Fort Lauderdale, Florida, Tortola, Pointe-à-Pitre, Castries, Scarborough, Santarém, Boca da Valeria, Manaus, Parintins, Iles du Salut, Bridgetown, Roseau and Gustavia.
How many days are spent at sea?
11 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It is a round-trip sailing from Fort Lauderdale, Florida.
How long is this cruise?
25 nights aboard Crystal Serenity.
When does this itinerary sail?
Upcoming departures include 18 Jan 2028. A NestCruise advisor can confirm current availability.