Cruise itinerary
23-Night South America Cruise from Valparaiso
23 nights · South America · 16 ports of call
23-night South America cruise aboard Crystal Serenity, departing Valparaiso and calling at Coquimbo, Iquique, Pisco, Callao, Salaverry and Guayaquil and 9 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Crystal Serenity
- Cruise line
- Crystal
- Duration
- 23 nights
- Region
- South America
- Departs
- Valparaiso
- Returns
- Fort Lauderdale, Florida
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Crystal Serenity sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1
Valparaiso
Depart 19:00
A historic port city on Chile's central coast, built across steep hills laced with funiculars and painted houses. A UNESCO World Heritage site, it serves as the gateway to Santiago and the Casablanca wine valley, with a busy working harbour below.
- Hillside funiculars
- Cerro Concepción
- Casablanca wineries
- Day2
Coquimbo
Arrive 09:00 · Depart 18:00
- Day3At sea
- Day4
Iquique
Arrive 08:00 · Depart 18:00
- Day5At sea
- Day6
Pisco
Arrive 08:00 · Depart 18:00
- Day7
Callao
Arrive 07:00 · Depart 19:00
Peru's chief seaport, on the Pacific beside Lima. Ships dock here for the colonial centre and museums of the capital, the cliff-top Miraflores district above the ocean, and onward journeys toward Machu Picchu and the Andean highlands.
- Gateway to Lima
- Miraflores
- Historic centre
- Day8
Salaverry
Arrive 11:00 · Depart 20:00
- Day9At sea
- Day10
Guayaquil
Arrive 07:00 · Depart 19:00
- Day11At sea
- Day12
Panama City
Arrive 17:00 · Depart 04:00
Panama's capital, where a glass-tower skyline meets the Pacific entrance to the famous canal. The colonial Casco Viejo quarter holds plazas and churches, while the Miraflores locks and the rainforest of Soberanía National Park sit close by.
- Panama Canal
- Casco Viejo
- Miraflores Locks
- Day13At sea
- Day14
Panama Canal Transit
- Day15
Puerto Limón
Arrive 08:00 · Depart 18:00
A Caribbean port on Costa Rica's humid eastern coast, the country's main Atlantic harbour. It opens onto rainforest, banana plantations and the canals of Tortuguero, with white-faced monkeys and sloths a frequent sight on excursions inland.
- Tortuguero canals
- Rainforest wildlife
- Banana country
- Day16At sea
- Day17
Roatán Island
Arrive 08:00 · Depart 18:00
An island off the northern coast of Honduras in the western Caribbean, part of the Bay Islands. Roatán is known for the Mesoamerican Barrier Reef just offshore, the dive sites and beaches around West End and West Bay, and forested inland hills.
- West Bay Beach
- Barrier reef diving
- West End
- Day18
Santo Tomás de Castilla
Arrive 08:00 · Depart 18:00
- Day19
Belize City
Arrive 08:00 · Depart 18:00
The largest city in Belize, on the Caribbean coast where the Belize River meets the sea. A tender port for many ships, it opens the way to the world's second-largest barrier reef, jungle Maya ruins and cave-tubing excursions inland.
- Barrier reef
- Maya ruins
- Cave tubing
- Day20
Cozumel
Arrive 09:00 · Depart 17:00
An island off Mexico's Yucatán coast in the Caribbean, a leading port for snorkelling and diving. Ships dock beside its reefs, part of the Mesoamerican system, with beach clubs, Mayan ruins and the resort strip of the Riviera Maya within reach.
- Coral reefs
- Mayan ruins
- Beach clubs
- Day21At sea
- Day22
Progreso
Arrive 08:00 · Depart 18:00
- Day23At sea
- Day24
Fort Lauderdale, Florida
Arrive 07:00
A South Florida port often called the yachting capital, fringed by canals and the long sands of Fort Lauderdale Beach. Port Everglades is among the world's busiest cruise gateways, with Las Olas Boulevard's shops and cafés minutes from the piers.
- Port Everglades
- Las Olas Boulevard
- Fort Lauderdale Beach
Upcoming departures
- 29 Nov 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
23-Night South America Cruise from Valparaiso FAQ
Which ports does this cruise visit?
This 23-night South America cruise calls at Valparaiso, Coquimbo, Iquique, Pisco, Callao, Salaverry, Guayaquil, Panama City, Panama Canal Transit, Puerto Limón, Roatán Island, Santo Tomás de Castilla, Belize City, Cozumel, Progreso and Fort Lauderdale, Florida.
How many days are spent at sea?
8 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Valparaiso and ends in Fort Lauderdale, Florida.
How long is this cruise?
23 nights aboard Crystal Serenity.
When does this itinerary sail?
Upcoming departures include 29 Nov 2027. A NestCruise advisor can confirm current availability.