

Cruise itinerary
12-Night Europe Cruise from Amsterdam
12 nights · Europe · 10 ports of call
12-night Europe cruise aboard Crystal Serenity, departing Amsterdam and calling at Antwerp, London (Greenwich), At Sea, La Rochelle, Bordeaux and Saint-Jean-de-Luz and 3 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Crystal Serenity
- Cruise line
- Crystal
- Duration
- 12 nights
- Region
- Europe · Northern Europe
- Departs
- Amsterdam
- Returns
- Lisbon
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Crystal Serenity sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Amsterdam
The Dutch capital, laced with concentric canals and gabled merchant houses from its 17th-century golden age. Most river sailings depart from here, leaving time for the Rijksmuseum, the Anne Frank House or a stroll through the Jordaan before lines cast off.
- Rijksmuseum
- Anne Frank House
- Jordaan canals
- Day2

Antwerp
A Belgian port city on the Scheldt and one of Europe's largest harbours. Its medieval Grote Markt and Gothic Cathedral of Our Lady anchor the old centre, in a city long tied to Rubens, diamond trading and Flemish art.
- Grote Markt
- Cathedral of Our Lady
- Diamond district
- Day3

Antwerp
A Belgian port city on the Scheldt and one of Europe's largest harbours. Its medieval Grote Markt and Gothic Cathedral of Our Lady anchor the old centre, in a city long tied to Rubens, diamond trading and Flemish art.
- Grote Markt
- Cathedral of Our Lady
- Diamond district
- Day4

London (Greenwich)
London's maritime quarter on the south bank of the Thames, where the city's historic deep-water moorings sit beside the Cutty Sark and the Old Royal Naval College. The Prime Meridian line runs through the hilltop observatory, with central London a short river boat ride upstream.
- Cutty Sark
- Royal Observatory
- Old Royal Naval College
- Day5
At Sea
- Day6

La Rochelle
- Day7

Bordeaux
A port city in southwest France set on the Garonne, ringed by the vineyards of its world-famous wine region. River ships moor near the centre, where the grand Place de la Bourse mirrors in a vast reflecting pool beside neoclassical quays.
- Place de la Bourse
- Wine country
- Garonne quays
- Day8

Bordeaux
A port city in southwest France set on the Garonne, ringed by the vineyards of its world-famous wine region. River ships moor near the centre, where the grand Place de la Bourse mirrors in a vast reflecting pool beside neoclassical quays.
- Place de la Bourse
- Wine country
- Garonne quays
- Day9
Saint-Jean-de-Luz
- Day10

Bilbao
The largest city of the Basque Country in northern Spain, set inland on the Nervión estuary. Once an industrial port, it was reshaped around Frank Gehry's titanium Guggenheim Museum, with pintxo bars and the old quarter close by.
- Guggenheim Museum
- Casco Viejo
- Pintxos bars
- Day11
At Sea
- Day12

Porto
Portugal's second city, climbing the granite hillsides above the Douro as it nears the Atlantic. It gives port wine its name; the riverside Ribeira district, the Dom Luís I iron bridge and the cellars of Vila Nova de Gaia define the waterfront.
- Ribeira district
- Dom Luís I Bridge
- Port wine cellars
- Day13

Lisbon
Portugal's hilly capital, spread across seven hills above the Tagus estuary. Yellow trams climb to the Alfama's tangled lanes and the Castle of São Jorge, while Belém's monastery and pastéis de nata anchor the riverside to the west.
- Alfama district
- Belém Tower
- Tram 28
Upcoming departures
- 17 Sep 2028
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
12-Night Europe Cruise from Amsterdam FAQ
Which ports does this cruise visit?
This 12-night Europe cruise calls at Amsterdam, Antwerp, London (Greenwich), At Sea, La Rochelle, Bordeaux, Saint-Jean-de-Luz, Bilbao, Porto and Lisbon.
How many days are spent at sea?
2 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Amsterdam and ends in Lisbon.
How long is this cruise?
12 nights aboard Crystal Serenity.
When does this itinerary sail?
Upcoming departures include 17 Sep 2028. A NestCruise advisor can confirm current availability.