Cruise itinerary
6-Night Caribbean Cruise from Tampa, Florida
6 nights · Caribbean · 4 ports of call
6-night Caribbean cruise aboard Serenade of the Seas, departing Tampa, Florida and calling at Cozumel, Roatán Island and Costa Maya.
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- No booking fees
- 10,000+ sailings
At a glance
- Cruise line
- Royal Caribbean International
- Duration
- 6 nights
- Region
- Caribbean · Americas · South America
- Departs
- Tampa, Florida
- Returns
- Tampa, Florida
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Serenade of the Seas sailing, typically within 24 hours.
Where this voyage takes you
- Family Friendly
Day-by-day itinerary
- Day1
Tampa, Florida
Depart 16:00
A port city on Florida's Gulf coast, set on a deep bay and a major embarkation point for Caribbean cruises. Tampa is known for the historic Cuban quarter of Ybor City, the Riverwalk, and the Spanish-Moorish towers of the old Tampa Bay Hotel.
- Ybor City
- Tampa Riverwalk
- Busch Gardens
- Day2At sea
- Day3
Cozumel
Arrive 07:00 · Depart 17:00
An island off Mexico's Yucatán coast in the Caribbean, a leading port for snorkelling and diving. Ships dock beside its reefs, part of the Mesoamerican system, with beach clubs, Mayan ruins and the resort strip of the Riviera Maya within reach.
- Coral reefs
- Mayan ruins
- Beach clubs
- Day4
Roatán Island
Arrive 08:00 · Depart 17:00
An island off the northern coast of Honduras in the western Caribbean, part of the Bay Islands. Roatán is known for the Mesoamerican Barrier Reef just offshore, the dive sites and beaches around West End and West Bay, and forested inland hills.
- West Bay Beach
- Barrier reef diving
- West End
- Day5
Costa Maya
Arrive 08:00 · Depart 17:00
A purpose-built cruise port on Mexico's Caribbean coast in Quintana Roo, on the southern Costa Maya. It serves as a gateway to Mayan ruins at Chacchoben and Kohunlich, plus nearby reef snorkelling and the laid-back fishing village of Mahahual.
- Chacchoben ruins
- Mahahual village
- Reef snorkelling
- Day6At sea
- Day7
Tampa, Florida
Arrive 07:00
A port city on Florida's Gulf coast, set on a deep bay and a major embarkation point for Caribbean cruises. Tampa is known for the historic Cuban quarter of Ybor City, the Riverwalk, and the Spanish-Moorish towers of the old Tampa Bay Hotel.
- Ybor City
- Tampa Riverwalk
- Busch Gardens
Upcoming departures
- 14 Nov 2027
- 20 Nov 2027
- 4 Dec 2027
- 15 Jan 2028
- 29 Jan 2028
- 12 Feb 2028
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
6-Night Caribbean Cruise from Tampa, Florida FAQ
Which ports does this cruise visit?
This 6-night Caribbean cruise calls at Tampa, Florida, Cozumel, Roatán Island and Costa Maya.
How many days are spent at sea?
2 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It is a round-trip sailing from Tampa, Florida.
How long is this cruise?
6 nights aboard Serenade of the Seas.
When does this itinerary sail?
Upcoming departures include 14 Nov 2027, 20 Nov 2027, 4 Dec 2027 and 15 Jan 2028. A NestCruise advisor can confirm current availability.