Cruises from Palermo
13 live cruises sail from Palermo — 7 to 21 nights, across 2 lines, through World Cruise. A NestCruise advisor narrows them to the one that fits.
13 sailings
MediterraneanMSC Cruises
7 nights: Barcelona & Civitavecchia, the Mediterranean
Aboard MSC Seaview
Round-trip from Palermo
Nov 2026 – Jul 2027Next 2 Nov 2026 · 14 more
EuropeMSC Cruises
7 nights: Barcelona & Naples, the Mediterranean
Aboard MSC Euribia
Round-trip from Palermo
Sails every two weeks, Nov 2026 – Jan 2028
EuropeMSC Cruises
7 nights: Naples & Barcelona, the Mediterranean
Aboard MSC Virtuosa
Round-trip from Palermo
Sails weekly, Apr 2027 – Nov 2027
EuropeMSC Cruises
7 nights: Ibiza & Civitavecchia, the Mediterranean
Aboard MSC Musica
Round-trip from Palermo
Sails weekly, Apr 2027 – Oct 2027
EuropePONANT EXPLORATIONS
5 nights: Valletta, the Mediterranean
Aboard Le Boréal
Palermo → Valletta
Rare itinerary
Jun 2027Next 1 Jun 2027
EuropePONANT EXPLORATIONS
7 nights: Nice, the Mediterranean
Aboard Le Ponant
Palermo → Nice
Rare itinerary
Aug 2027Next 24 Aug 2027
World CruiseMSC Cruises
20 nights: Barcelona & Rio de Janeiro
Aboard MSC Splendida
Palermo → Montevideo
Rare itinerary
Nov 2026Next 12 Nov 2026
EuropeMSC Cruises
7 nights: Barcelona & Naples, the Mediterranean
Aboard MSC Seaview
Round-trip from Palermo
Sails weekly, Nov 2027 – Dec 2027
EuropeMSC Cruises
20 nights: Barcelona & Rio de Janeiro, the Mediterranean
Aboard MSC Virtuosa
Palermo → Rio de Janeiro
Rare itinerary
Nov 2027Next 12 Nov 2027
EuropePONANT EXPLORATIONS
7 nights in the Mediterranean
Aboard Le Ponant
Palermo → Lavrion
Rare itinerary
Jun 2027Next 8 Jun 2027
World CruiseMSC Cruises
21 nights: Barcelona & Rio de Janeiro
Aboard MSC Splendida
Palermo → Buenos Aires
Rare itinerary
Nov 2026Next 12 Nov 2026
Frequently asked
- How many cruises from Palermo does NestCruise have?
- 13 live sailings, 7 to 21 nights. A NestCruise advisor narrows them to the one that fits.
- Which cruise lines sail from Palermo?
- MSC Cruises and PONANT EXPLORATIONS, among others.
- How long are cruises from Palermo?
- Most run 7 to 21 nights.
- How much do cruises from Palermo cost?
- NestCruise doesn't publish fares — it's a quote-only concierge. Share your dates and party size and an advisor prices your exact sailing at no cost.