

Cruise itinerary
20-Night Europe Cruise from Palermo
20 nights · Europe · 10 ports of call
20-night Europe cruise aboard MSC Virtuosa, departing Palermo and calling at Naples, Livorno, Marseille, Barcelona, Málaga and Santa Cruz de Tenerife and 3 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Ship
- MSC Virtuosa
- Cruise line
- MSC Cruises
- Duration
- 20 nights
- Region
- Europe · Southern Europe · Mediterranean · World Cruise
- Departs
- Palermo
- Returns
- Rio de Janeiro
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact MSC Virtuosa sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Palermo
Depart 18:00
The capital of Sicily, a port city layered with Arab, Norman, and Baroque history on the island's north coast. Palermo is known for its mosaic-rich Cappella Palatina, lively street-food markets, and the Norman cathedral at nearby Monreale.
- Cappella Palatina
- Ballarò market
- Monreale mosaics
- Day2

Naples
Arrive 06:00 · Depart 17:00
A southern Italian port on its namesake bay, in the shadow of Mount Vesuvius. Ships dock near the historic centre, the gateway to Pompeii, the cliffs of the Amalfi Coast and the island of Capri, in a city that claims to have invented pizza.
- Mount Vesuvius
- Pompeii
- Gateway to Capri
- Day3

Livorno
Arrive 09:00 · Depart 20:00
A Tuscan port on the Ligurian Sea and the gateway to Florence and Pisa. Ships dock here for excursions to Renaissance galleries and the Leaning Tower, while Livorno itself is known for its canal district and a seafood stew called cacciucco.
- Gateway to Florence
- Pisa excursions
- Venezia Nuova canals
- Day4

Marseille
Arrive 10:00 · Depart 18:00
France's oldest city and biggest Mediterranean port, set around the old harbour of the Vieux-Port. The hilltop basilica of Notre-Dame de la Garde watches over the bay, with the Calanques inlets and bouillabaisse stalls a short way off.
- Vieux-Port
- Notre-Dame de la Garde
- Calanques
- Day5

Barcelona
Arrive 07:00 · Depart 19:00
Catalonia's seafront capital and one of the Mediterranean's busiest cruise homeports. Gaudí's Sagrada Família and Park Güell crown the city, while the tree-lined Ramblas and the Gothic Quarter's medieval lanes lie a short ride from the terminal.
- Sagrada Família
- La Rambla
- Gothic Quarter
- Day6At sea
- Day7

Málaga
Arrive 07:00 · Depart 17:00
A port city on Spain's Costa del Sol and the birthplace of Picasso. Cruise ships berth near the centre, where a hilltop Moorish fortress, the cathedral and the Picasso Museum sit close to broad city beaches and fried-fish chiringuitos.
- Alcazaba fortress
- Picasso Museum
- Costa del Sol beaches
- Day8At sea
- Day9

Santa Cruz de Tenerife
Arrive 09:00 · Depart 19:00
The capital of Tenerife in Spain's Canary Islands, a volcanic Atlantic port off northwest Africa. Santa Cruz is known for its sail-shaped Auditorio concert hall, the palm-lined Plaza de España, and the road up to Mount Teide, Spain's highest peak.
- Auditorio de Tenerife
- Mount Teide
- Plaza de España
- Day10At sea
- Day11At sea
- Day12At sea
- Day13At sea
- Day14At sea
- Day15At sea
- Day16

Maceió
Arrive 08:00 · Depart 19:00
The capital of Alagoas on Brazil's north-east coast, fringed by white sand and warm reef-protected lagoons. Pajuçara and Ponta Verde beaches draw swimmers, and jangada rafts carry visitors out to the natural tidal pools offshore.
- Pajuçara beach
- Natural pools
- Jangada rafts
- Day17At sea
- Day18

Salvador de Bahia
Arrive 07:00 · Depart 19:00
Brazil's first colonial capital, set on a bluff above the Bay of All Saints. The cobbled Pelourinho district holds pastel baroque churches and the rhythms of Afro-Brazilian culture, with capoeira, candomblé and acarajé stalls woven into daily life.
- Pelourinho
- Elevador Lacerda
- Acarajé
- Day19At sea
- Day20At sea
- Day21

Rio de Janeiro
Arrive 08:00
Brazil's great coastal city, set between forested mountains and the Atlantic. The Christ the Redeemer statue looks down from Corcovado, Sugarloaf rises over the harbour mouth, and the sands of Copacabana and Ipanema run along the city's southern edge.
- Christ the Redeemer
- Sugarloaf Mountain
- Copacabana Beach
Upcoming departures
- 12 Nov 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
20-Night Europe Cruise from Palermo FAQ
Which ports does this cruise visit?
This 20-night Europe cruise calls at Palermo, Naples, Livorno, Marseille, Barcelona, Málaga, Santa Cruz de Tenerife, Maceió, Salvador de Bahia and Rio de Janeiro.
How many days are spent at sea?
11 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Palermo and ends in Rio de Janeiro.
How long is this cruise?
20 nights aboard MSC Virtuosa.
When does this itinerary sail?
Upcoming departures include 12 Nov 2027. A NestCruise advisor can confirm current availability.