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Cruises to Pátmos

75 live cruises call at Pátmos — 7 to 28 nights, departing 11 ports, across 9 lines. A NestCruise advisor narrows them to the one that fits.

75 sailings
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Iconic Greek Islands - 3NightsMediterranean

Celestyal Cruises

3 nights: Mykonos & Santorini, the Mediterranean

Aboard Celestyal Discovery

Round-trip from Piraeus

Aug 2026 – Nov 2027Next 7 Aug 2026 · 51 more
7-Night Mediterranean CruiseMediterranean

Silversea

7 nights: Piraeus & Santorini, the Mediterranean

Aboard Silver Nova

Round-trip from Piraeus

Sails monthly, Aug 2026 – Sep 2027
Greek Islands & Turkish CoastlinesEurope

Emerald Cruises

7 nights: Mykonos & Santorini, the Mediterranean

Aboard Emerald Azzurra

Round-trip from Piraeus

Aug 2026 – Aug 2027Next 29 Aug 2026 · 4 more
7-Night Italy, Malta, Croatia & MontenegroMEDITERRANEAN

Seabourn

7 nights: Dubrovnik & Mykonos, the Mediterranean

Aboard Seabourn Ovation

Civitavecchia → Piraeus

May 2027 – Sep 2028Next 8 May 2027 · 5 more
Emerald Raiya Inaugural Voyage: Greek Islands & Turkish CoastlinesEurope

Emerald Cruises

7 nights: Mykonos & Santorini, the Mediterranean

Aboard Emerald Raiya

Round-trip from Piraeus

Jun 2027 – Oct 2027Next 19 Jun 2027 · 3 more
At the heart of the Greek islandsEurope

PONANT EXPLORATIONS

7 nights: Athens, the Mediterranean

Aboard Le Dumont-d'Urville

Round-trip from Athens

Rare itinerary
Jun 2027 – Jul 2027Next 22 Jun 2027 · 2 more
9-Night Mediterranean CruiseMediterranean

Oceania Cruises

9 nights: Mykonos & Istanbul, the Mediterranean

Aboard Oceania Sirena

Civitavecchia → Istanbul

Rare itinerary
Mar 2027 – Jul 2027Next 29 Mar 2027 · 2 more
7-Night Greek Islands CruiseGreek Islands

Azamara

7 nights: Rhodes & Santorini, the Greek Isles

Aboard Azamara Onward

Round-trip from Piraeus

Rare itinerary
Sep 2026 – Oct 2027Next 19 Sep 2026 · 1 more
7-Night Greece & Dalmatian DelightsMEDITERRANEAN

Seabourn

7 nights: Mykonos & Istanbul, the Mediterranean

Aboard Seabourn Quest

Piraeus → Venice

Rare itinerary
Aug 2026Next 16 Aug 2026
Piraeus (Athens) → Fusina (Venice)Mediterranean & Western Europe

Explora Journeys

14 nights: Mykonos & Kotor

Aboard EXPLORA I

Piraeus → Fusina

Overnight in MykonosRare itinerary
Jun 2028 – Sep 2028Next 24 Jun 2028 · 1 more
La Valletta → Piraeus (Athens)Mediterranean & Western Europe

Explora Journeys

5 nights: Mykonos & Santorini

Aboard EXPLORA II

Valletta → Piraeus

Rare itinerary
Mar 2027Next 20 Mar 2027
Greece Intensive Cruise: Syros, Patmos & RhodesEurope

Azamara

7 nights: Rhodes & Santorini, the Mediterranean

Aboard Azamara Journey

Round-trip from Piraeus

Rare itinerary
May 2028Next 6 May 2028
Greece Intensive Cruise: Santorini, Rhodes & MykonosEurope

Azamara

7 nights: Santorini & Mykonos, the Mediterranean

Aboard Azamara Quest

Round-trip from Piraeus

Rare itinerary
Oct 2026Next 24 Oct 2026
Cruising the Greek Islands of the Southern Aegean – with Smithsonian JourneysEurope

PONANT EXPLORATIONS

7 nights: Santorini & Mykonos, the Mediterranean

Aboard Le Lapérouse

Round-trip from Athens

Rare itinerary
Sep 2027Next 8 Sep 2027
Greeks & ByzantinesEurope

Oceania Cruises

7 nights: Rhodes & Istanbul, the Mediterranean

Aboard Oceania Sonata

Piraeus → Istanbul

Overnight in IstanbulRare itinerary
Oct 2027Next 14 Oct 2027
Grecian RhapsodyEurope

Regent Seven Seas Cruises

7 nights: Piraeus & Santorini, the Mediterranean

Aboard Seven Seas Splendor

Round-trip from Piraeus

Rare itinerary
Aug 2026Next 4 Aug 2026
9-Night Mediterranean CruiseMediterranean

Emerald Cruises

9 nights: Mykonos & Santorini, the Mediterranean

Aboard Emerald Kaia

Piraeus → Larnaca

Rare itinerary
Oct 2026Next 21 Oct 2026
Civitavecchia to AthensEurope

Silversea

12 nights: Civitavecchia & Mykonos, the Mediterranean

Aboard Silver Dawn

Civitavecchia → Piraeus

Rare itinerary
Oct 2027Next 10 Oct 2027
Iconic Greek Islands - 4NightsMediterranean

Celestyal Cruises

4 nights: Mykonos & Santorini, the Mediterranean

Aboard Celestyal Discovery

Round-trip from Piraeus

Aug 2026 – Nov 2027Next 3 Aug 2026 · 50 more
Discover the Eastern MediterraneanEurope

Emerald Cruises

14 nights: Mykonos & Santorini, the Mediterranean

Aboard Emerald Azzurra

Piraeus → Dubrovnik

Rare itinerary
May 2027 – Oct 2027Next 29 May 2027 · 2 more
7-Night Hidden Gems Of Turkey & GreeceMEDITERRANEAN

Seabourn

7 nights: Istanbul & Santorini, the Mediterranean

Aboard Seabourn Ovation

Istanbul → Piraeus

May 2027 – Sep 2028Next 29 May 2027 · 5 more
Istanbul to Athens AdventureEurope

Emerald Cruises

7 nights: Istanbul & Mykonos, the Mediterranean

Aboard Emerald Raiya

Istanbul → Piraeus

Aug 2027 – Oct 2028Next 21 Aug 2027 · 3 more
Cruising the Greek Islands of the Southern Aegean – with Smithsonian JourneysEurope

PONANT EXPLORATIONS

7 nights: Athens & Mykonos, the Mediterranean

Aboard Le Dumont-d'Urville

Round-trip from Athens

Rare itinerary
Oct 2026 – Jul 2027Next 8 Oct 2026 · 1 more
Greece Intensive Cruise: Rhodes, Patmos & MykonosEurope

Azamara

7 nights: Rhodes & Mykonos, the Mediterranean

Aboard Azamara Onward

Round-trip from Piraeus

Rare itinerary
Oct 2028Next 14 Oct 2028
7-Night Greek Isles & EphesusMEDITERRANEAN

Seabourn

7 nights: Mykonos & Istanbul, the Mediterranean

Aboard Seabourn Quest

Round-trip from Piraeus

Rare itinerary
Oct 2026Next 11 Oct 2026
Fusina (Venice) → Piraeus (Athens)Mediterranean & Western Europe

Explora Journeys

14 nights: Dubrovnik & Rhodes

Aboard EXPLORA I

Fusina → Piraeus

Rare itinerary
Jun 2028 – Sep 2028Next 17 Jun 2028 · 1 more
Barcelona → La VallettaMediterranean & Western Europe

Explora Journeys

6 nights: Barcelona & Mykonos

Aboard EXPLORA II

Barcelona → Piraeus

Rare itinerary
Mar 2027Next 14 Mar 2027
Greece & Croatia Combination Cruise: Rhodes, Santorini & HvarEurope

Azamara

16 nights: Santorini & Dubrovnik, the Mediterranean

Aboard Azamara Journey

Piraeus → Fusina

Rare itinerary
May 2028Next 6 May 2028
Greece & Turkey Cruise: Athens, Istanbul & SyrosEurope

Azamara

11 nights: Piraeus & Istanbul, the Mediterranean

Aboard Azamara Quest

Round-trip from Piraeus

Overnight in IstanbulRare itinerary
Oct 2026Next 3 Oct 2026
At the heart of the Greek islandsEurope

PONANT EXPLORATIONS

7 nights: Athens, the Mediterranean

Aboard Le Lapérouse

Round-trip from Athens

Rare itinerary
Aug 2027Next 25 Aug 2027
Crowning Ancient CulturesWorld Cruise

Oceania Cruises

36 nights: Barcelona & Mykonos

Aboard Oceania Sonata

Southampton → Istanbul

Overnight in BordeauxRare itinerary
Sep 2027Next 15 Sep 2027
A voyage from Greece to CyprusEurope

Emerald Cruises

10 nights: Mykonos & Santorini, the Mediterranean

Aboard Emerald Kaia

Piraeus → Larnaca

Overnight in LarnacaRare itinerary
Oct 2026Next 21 Oct 2026
Iconic Greek Islands - 3Nights (Mar & Nov)Europe

Celestyal Cruises

3 nights: Mykonos & Santorini, the Mediterranean

Aboard Celestyal Discovery

Mykonos → Athens

Oct 2026 – Nov 2026Next 23 Oct 2026 · 5 more
Athens to Istanbul AdventureEurope

Emerald Cruises

7 nights: Santorini & Mykonos, the Mediterranean

Aboard Emerald Azzurra

Piraeus → Istanbul

Rare itinerary
Aug 2026Next 8 Aug 2026
7-Night Crete, Mykonos & Evening At EphesusMEDITERRANEAN

Seabourn

7 nights: Mykonos & Istanbul, the Mediterranean

Aboard Seabourn Ovation

Piraeus → Civitavecchia

Rare itinerary
Sails monthly, May 2028 – Jul 2028
Yachting the less-travelled Greek Isles, Mykonos and TurkeyEurope

Emerald Cruises

10 nights: Piraeus & Mykonos, the Mediterranean

Aboard Emerald Raiya

Round-trip from Piraeus

Rare itinerary
Sep 2027 – May 2028Next 15 Sep 2027 · 1 more
Cruising the Aegean: Turkey and the Greek Isles – with Smithsonian JourneysEurope

PONANT EXPLORATIONS

7 nights: Mykonos & Istanbul, the Mediterranean

Aboard Le Dumont-d'Urville

Athens → Istanbul

Rare itinerary
Oct 2027Next 14 Oct 2027
Greece Intensive Cruise: Thessaloniki, Patmos & MykonosEurope

Azamara

8 nights: Istanbul & Mykonos, the Mediterranean

Aboard Azamara Onward

Istanbul → Piraeus

Rare itinerary
Apr 2027Next 30 Apr 2027
7-Night Turkey & Greek Isle GemsMEDITERRANEAN

Seabourn

7 nights: Istanbul & Rhodes, the Mediterranean

Aboard Seabourn Quest

Istanbul → Piraeus

Rare itinerary
Oct 2026Next 18 Oct 2026
Piraeus (Athens) → Fusina (Venice)Mediterranean & Western Europe

Explora Journeys

14 nights: Mykonos & Kotor

Aboard EXPLORA I

Piraeus → Fusina

Overnight in MykonosRare itinerary
May 2028Next 13 May 2028
Piraeus (Athens) → Fusina (Venice)Mediterranean & Western Europe

Explora Journeys

7 nights: Dubrovnik & Mykonos

Aboard EXPLORA II

Round-trip from Piraeus

Rare itinerary
Aug 2027Next 23 Aug 2027
Mediterranean Combination Cruise: Barcelona, Venice & AthensEurope

Azamara

31 nights: Barcelona & Dubrovnik, the Mediterranean

Aboard Azamara Quest

Barcelona → Piraeus

Overnight in IstanbulRare itinerary
Sep 2026Next 13 Sep 2026
Discover the Wonders of the Mediterranean & Red SeaEurope

Emerald Cruises

21 nights: Mykonos & Santorini, the Mediterranean

Aboard Emerald Kaia

Piraeus → 'Aqaba

Overnight in LarnacaRare itinerary
Oct 2026Next 21 Oct 2026
Iconic Greek Islands - 4Nights (Mar & Nov)Europe

Celestyal Cruises

4 nights: Mykonos & Santorini, the Mediterranean

Aboard Celestyal Discovery

Mykonos → Athens

Oct 2026 – Nov 2026Next 26 Oct 2026 · 5 more
7-Night Mediterranean CruiseMediterranean

Emerald Cruises

7 nights: Istanbul & Mykonos, the Mediterranean

Aboard Emerald Azzurra

Istanbul → Piraeus

Rare itinerary
Aug 2026Next 15 Aug 2026
7-Night Crete, Mykonos & EphesusMEDITERRANEAN

Seabourn

7 nights: Mykonos & Istanbul, the Mediterranean

Aboard Seabourn Ovation

Piraeus → Barcelona

Rare itinerary
Oct 2027 – Oct 2028Next 16 Oct 2027 · 2 more
Aegean Odyssey: Athens to IstanbulEurope

Emerald Cruises

10 nights: Santorini & Istanbul, the Mediterranean

Aboard Emerald Raiya

Piraeus → Istanbul

Rare itinerary
Oct 2027 – Jun 2028Next 6 Oct 2027 · 1 more
Greece & Turkey Cruise: Mykonos, Volos & IstanbulEurope

Azamara

9 nights: Mykonos & Istanbul, the Mediterranean

Aboard Azamara Onward

Round-trip from Piraeus

Overnight in IstanbulRare itinerary
Jun 2028Next 29 Jun 2028

Frequently asked

How many cruises to Pátmos does NestCruise have?
75 live sailings, 7 to 28 nights. A NestCruise advisor narrows them to the one that fits.
Which cruise lines visit Pátmos?
Azamara, Emerald Cruises, Explora Journeys and Seabourn, among others.
How long are cruises to Pátmos?
Most run 7 to 28 nights.
How much do cruises to Pátmos cost?
NestCruise doesn't publish fares — it's a quote-only concierge. Share your dates and party size and an advisor prices your exact sailing at no cost.