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Cruises to Pátmos

61 live cruises call at Pátmos — 7 to 21 nights, departing 11 ports, across 8 lines. A NestCruise advisor narrows them to the one that fits.

61 sailings
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Iconic Greek Islands - 3NightsMediterranean

Celestyal Cruises

3 nights: Mykonos & Santorini, the Mediterranean

Aboard Celestyal Discovery

Round-trip from Piraeus

↓ $711 this month

from$289pp · cruise fare≈ $96/night pp

Fares checked nightly

Nov 2026 – Nov 2027Next 6 Nov 2026 · 38 more
7-Night Mediterranean CruiseMediterranean

Silversea

7 nights: Piraeus & Santorini, the Mediterranean

Aboard Silver Nova

Round-trip from Piraeus

↓ $3,000 this month

from$4,200pp · cruise fare≈ $600/night pp

Fares checked nightly

May 2027 – Sep 2027Next 15 May 2027 · 7 more
Greek Islands & Turkish CoastlinesEurope

Emerald Cruises

7 nights: Mykonos & Santorini, the Mediterranean

Aboard Emerald Azzurra

Round-trip from Piraeus

↓ $1,101 this monthIncludes Preferred Savings

from$7,194pp · cruise fare≈ $1,028/night pp

Fares checked nightly

May 2027 – Aug 2027Next 29 May 2027 · 2 more
7-Night Italy, Malta, Croatia & MontenegroMEDITERRANEAN

Seabourn

7 nights: Dubrovnik & Mykonos, the Mediterranean

Aboard Seabourn Ovation

Civitavecchia → Piraeus

from$4,498pp · cruise fare≈ $643/night pp

Fares checked nightly

May 2027 – Sep 2028Next 8 May 2027 · 5 more
Emerald Raiya Inaugural Voyage: Greek Islands & Turkish CoastlinesEurope

Emerald Cruises

7 nights: Mykonos & Santorini, the Mediterranean

Aboard Emerald Raiya

Round-trip from Piraeus

↓ $683 this monthIncludes Preferred Savings

from$6,762pp · cruise fare≈ $966/night pp

Fares checked nightly

Jun 2027 – Oct 2027Next 19 Jun 2027 · 3 more
At the heart of the Greek islandsEurope

PONANT EXPLORATIONS

7 nights: Athens, the Mediterranean

Aboard Le Dumont-d'Urville

Round-trip from Athens

Rare itinerary
Jun 2027 – Jul 2027Next 22 Jun 2027 · 2 more
9-Night Mediterranean CruiseMediterranean

Oceania Cruises

9 nights: Mykonos & Istanbul, the Mediterranean

Aboard Oceania Sirena

Civitavecchia → Istanbul

Rare itinerary
Mar 2027 – Jul 2027Next 29 Mar 2027 · 2 more
7-Night Greek Islands CruiseGreek Islands

Azamara

7 nights: Rhodes & Santorini, the Greek Isles

Aboard Azamara Onward

Round-trip from Piraeus

Rare itinerary

from$3,199pp · cruise fare≈ $457/night pp

Fares checked nightly

Oct 2027Next 9 Oct 2027
Piraeus (Athens) → Fusina (Venice)Mediterranean & Western Europe

Explora Journeys

14 nights: Mykonos & Kotor

Aboard EXPLORA I

Piraeus → Fusina

↓ $5,545 this monthSummer 2028

from$8,950pp · cruise fare≈ $639/night pp

Fares checked nightly

Jun 2028 – Sep 2028Next 24 Jun 2028 · 1 more
La Valletta → Piraeus (Athens)Mediterranean & Western Europe

Explora Journeys

5 nights: Mykonos & Santorini

Aboard EXPLORA II

Valletta → Piraeus

↓ $1,560 this monthWinter 2026-2027

from$2,890pp · cruise fare≈ $578/night pp

Fares checked nightly

Mar 2027Next 20 Mar 2027
Greece Intensive Cruise: Syros, Patmos & RhodesEurope

Azamara

7 nights: Rhodes & Santorini, the Mediterranean

Aboard Azamara Journey

Round-trip from Piraeus

↓ $1,062 this monthRare itinerary

from$2,569pp · cruise fare≈ $367/night pp

Fares checked nightly

May 2028Next 6 May 2028
Cruising the Greek Islands of the Southern Aegean – with Smithsonian JourneysEurope

PONANT EXPLORATIONS

7 nights: Santorini & Mykonos, the Mediterranean

Aboard Le Lapérouse

Round-trip from Athens

Rare itinerary
Sep 2027Next 8 Sep 2027
Greeks & ByzantinesEurope

Oceania Cruises

7 nights: Rhodes & Istanbul, the Mediterranean

Aboard Oceania Sonata

Piraeus → Istanbul

Overnight in IstanbulRare itinerary
Oct 2027Next 14 Oct 2027
Civitavecchia to AthensEurope

Silversea

12 nights: Civitavecchia & Mykonos, the Mediterranean

Aboard Silver Dawn

Civitavecchia → Piraeus

↓ $2,500 this monthRare itinerary

from$8,800pp · cruise fare≈ $733/night pp

Fares checked nightly

Oct 2027Next 10 Oct 2027
Iconic Greek Islands - 4NightsMediterranean

Celestyal Cruises

4 nights: Mykonos & Santorini, the Mediterranean

Aboard Celestyal Discovery

Round-trip from Piraeus

↓ $711 this month

from$289pp · cruise fare≈ $72/night pp

Fares checked nightly

Nov 2026 – Nov 2027Next 2 Nov 2026 · 37 more
Discover the Eastern MediterraneanEurope

Emerald Cruises

14 nights: Mykonos & Santorini, the Mediterranean

Aboard Emerald Azzurra

Piraeus → Dubrovnik

Rare itinerary

from$41,580pp · cruise fare≈ $2,970/night pp

Fares checked nightly

May 2027 – Oct 2027Next 29 May 2027 · 2 more
7-Night Hidden Gems Of Turkey & GreeceMEDITERRANEAN

Seabourn

7 nights: Istanbul & Santorini, the Mediterranean

Aboard Seabourn Ovation

Istanbul → Piraeus

from$4,498pp · cruise fare≈ $643/night pp

Fares checked nightly

May 2027 – Sep 2028Next 29 May 2027 · 5 more
Istanbul to Athens AdventureEurope

Emerald Cruises

7 nights: Istanbul & Mykonos, the Mediterranean

Aboard Emerald Raiya

Istanbul → Piraeus

↓ $683 this monthIncludes Preferred Savings

from$6,762pp · cruise fare≈ $966/night pp

Fares checked nightly

Aug 2027 – Oct 2028Next 21 Aug 2027 · 3 more
Cruising the Greek Islands of the Southern Aegean – with Smithsonian JourneysEurope

PONANT EXPLORATIONS

7 nights: Athens & Mykonos, the Mediterranean

Aboard Le Dumont-d'Urville

Round-trip from Athens

Rare itinerary
Jul 2027Next 6 Jul 2027
Greece Intensive Cruise: Rhodes, Patmos & MykonosEurope

Azamara

7 nights: Rhodes & Mykonos, the Mediterranean

Aboard Azamara Onward

Round-trip from Piraeus

↓ $1,142 this monthRare itinerary

from$2,809pp · cruise fare≈ $401/night pp

Fares checked nightly

Oct 2028Next 14 Oct 2028
Fusina (Venice) → Piraeus (Athens)Mediterranean & Western Europe

Explora Journeys

14 nights: Dubrovnik & Rhodes

Aboard EXPLORA I

Fusina → Piraeus

↓ $5,545 this monthSummer 2028

from$8,950pp · cruise fare≈ $639/night pp

Fares checked nightly

Jun 2028 – Sep 2028Next 17 Jun 2028 · 1 more
Barcelona → La VallettaMediterranean & Western Europe

Explora Journeys

6 nights: Barcelona & Mykonos

Aboard EXPLORA II

Barcelona → Piraeus

↓ $1,910 this monthWinter 2026-2027

from$3,540pp · cruise fare≈ $590/night pp

Fares checked nightly

Mar 2027Next 14 Mar 2027
Greece & Croatia Combination Cruise: Rhodes, Santorini & HvarEurope

Azamara

16 nights: Santorini & Dubrovnik, the Mediterranean

Aboard Azamara Journey

Piraeus → Fusina

↓ $2,576 this monthRare itinerary

from$6,229pp · cruise fare≈ $389/night pp

Fares checked nightly

May 2028Next 6 May 2028
At the heart of the Greek islandsEurope

PONANT EXPLORATIONS

7 nights: Athens, the Mediterranean

Aboard Le Lapérouse

Round-trip from Athens

Rare itinerary
Aug 2027Next 25 Aug 2027
Crowning Ancient CulturesWorld Cruise

Oceania Cruises

36 nights: Barcelona & Mykonos

Aboard Oceania Sonata

Southampton → Istanbul

Overnight in BordeauxRare itinerary
Sep 2027Next 15 Sep 2027
Iconic Greek Islands - 3Nights (Mar & Nov)Europe

Celestyal Cruises

3 nights: Mykonos & Santorini, the Mediterranean

Aboard Celestyal Discovery

Mykonos → Athens

Rare itinerary
Nov 2026Next 6 Nov 2026 · 1 more
Discover the Charming MediterraneanEurope

Emerald Cruises

17 nights: Mykonos & Santorini, the Mediterranean

Aboard Emerald Azzurra

Valletta → Piraeus

Rare itinerary
May 2027Next 19 May 2027
7-Night Crete, Mykonos & Evening At EphesusMEDITERRANEAN

Seabourn

7 nights: Mykonos & Istanbul, the Mediterranean

Aboard Seabourn Ovation

Piraeus → Civitavecchia

Rare itinerary

from$5,498pp · cruise fare≈ $785/night pp

Fares checked nightly

Sails monthly, May 2028 – Jul 2028
Yachting the less-travelled Greek Isles, Mykonos and TurkeyEurope

Emerald Cruises

10 nights: Piraeus & Mykonos, the Mediterranean

Aboard Emerald Raiya

Round-trip from Piraeus

↓ $1,002 this monthIncludes Preferred Savings

from$6,493pp · cruise fare≈ $649/night pp

Fares checked nightly

Sep 2027 – May 2028Next 15 Sep 2027 · 1 more
Cruising the Aegean: Turkey and the Greek Isles – with Smithsonian JourneysEurope

PONANT EXPLORATIONS

7 nights: Mykonos & Istanbul, the Mediterranean

Aboard Le Dumont-d'Urville

Athens → Istanbul

Rare itinerary
Oct 2027Next 14 Oct 2027
Greece Intensive Cruise: Thessaloniki, Patmos & MykonosEurope

Azamara

8 nights: Istanbul & Mykonos, the Mediterranean

Aboard Azamara Onward

Istanbul → Piraeus

Rare itinerary

from$3,189pp · cruise fare≈ $399/night pp

Fares checked nightly

Apr 2027Next 30 Apr 2027
Piraeus (Athens) → Fusina (Venice)Mediterranean & Western Europe

Explora Journeys

14 nights: Mykonos & Kotor

Aboard EXPLORA I

Piraeus → Fusina

↓ $5,453 this monthOvernight in Mykonos

from$8,795pp · cruise fare≈ $628/night pp

Fares checked nightly

May 2028Next 13 May 2028
Piraeus (Athens) → Fusina (Venice)Mediterranean & Western Europe

Explora Journeys

7 nights: Dubrovnik & Mykonos

Aboard EXPLORA II

Round-trip from Piraeus

↓ $1,615 this monthAn Invitation to

from$4,835pp · cruise fare≈ $691/night pp

Fares checked nightly

Aug 2027Next 23 Aug 2027
Iconic Greek Islands - 4Nights (Mar & Nov)Europe

Celestyal Cruises

4 nights: Mykonos & Santorini, the Mediterranean

Aboard Celestyal Discovery

Mykonos → Athens

Nov 2026Next 2 Nov 2026 · 3 more
Epic Voyage: Athens to VeniceEurope

Emerald Cruises

21 nights: Mykonos & Santorini, the Mediterranean

Aboard Emerald Azzurra

Piraeus → Venice

Overnight in DubrovnikRare itinerary
May 2027Next 29 May 2027
7-Night Crete, Mykonos & EphesusMEDITERRANEAN

Seabourn

7 nights: Mykonos & Istanbul, the Mediterranean

Aboard Seabourn Ovation

Piraeus → Barcelona

Rare itinerary

from$4,498pp · cruise fare≈ $643/night pp

Fares checked nightly

Oct 2027 – Oct 2028Next 16 Oct 2027 · 2 more
Aegean Odyssey: Athens to IstanbulEurope

Emerald Cruises

10 nights: Santorini & Istanbul, the Mediterranean

Aboard Emerald Raiya

Piraeus → Istanbul

↓ $1,002 this monthIncludes Preferred Savings

from$6,493pp · cruise fare≈ $649/night pp

Fares checked nightly

Oct 2027 – Jun 2028Next 6 Oct 2027 · 1 more
Greece & Turkey Cruise: Mykonos, Volos & IstanbulEurope

Azamara

9 nights: Mykonos & Istanbul, the Mediterranean

Aboard Azamara Onward

Round-trip from Piraeus

↓ $1,470 this monthOvernight in Istanbul

from$3,609pp · cruise fare≈ $401/night pp

Fares checked nightly

Jun 2028Next 29 Jun 2028
Piraeus (Athens) → Fusina (Venice)Mediterranean & Western Europe

Explora Journeys

14 nights: Mykonos & Kotor

Aboard EXPLORA I

Piraeus → Fusina

↓ $5,608 this monthOvernight in Mykonos

from$9,040pp · cruise fare≈ $646/night pp

Fares checked nightly

Aug 2028Next 5 Aug 2028
Istanbul → Piraeus (Athens)Mediterranean & Western Europe

Explora Journeys

7 nights: Istanbul & Mykonos

Aboard EXPLORA II

Istanbul → Piraeus

↓ $2,010 this monthAn Invitation to

from$4,690pp · cruise fare≈ $670/night pp

Fares checked nightly

Oct 2027Next 11 Oct 2027
7-Night Dalmatian Gems, Montenegro & GreeceMEDITERRANEAN

Seabourn

7 nights: Venice & Mykonos, the Mediterranean

Aboard Seabourn Ovation

Venice → Lisbon

Rare itinerary

from$8,838pp · cruise fare≈ $1,263/night pp

Fares checked nightly

Oct 2027Next 9 Oct 2027
Discover the Eastern MediterraneanEurope

Emerald Cruises

14 nights: Dubrovnik & Mykonos, the Mediterranean

Aboard Emerald Raiya

Dubrovnik → Piraeus

Rare itinerary
Sails weekly, Jul 2027
Greece & Turkey Cruise: Athens, Istanbul & PatmosEurope

Azamara

10 nights: Piraeus & Istanbul, the Mediterranean

Aboard Azamara Onward

Round-trip from Piraeus

↓ $1,769 this monthOvernight in Istanbul

from$4,329pp · cruise fare≈ $433/night pp

Fares checked nightly

Sep 2028Next 27 Sep 2028
Istanbul → Piraeus (Athens)Mediterranean & Western Europe

Explora Journeys

7 nights: Istanbul & Mykonos

Aboard EXPLORA II

Istanbul → Piraeus

↓ $1,610 this monthVirtuoso

from$6,440pp · cruise fare≈ $920/night pp

Fares checked nightly

Sep 2027Next 13 Sep 2027
8-Night Croatia, Montenegro, Italy & GreeceMEDITERRANEAN

Seabourn

8 nights: Dubrovnik & Mykonos, the Mediterranean

Aboard Seabourn Ovation

Round-trip from Dubrovnik

Rare itinerary

from$5,998pp · cruise fare≈ $750/night pp

Fares checked nightly

Aug 2027Next 6 Aug 2027
14-Night Mediterranean CruiseMediterranean

Emerald Cruises

14 nights: Dubrovnik & Mykonos, the Mediterranean

Aboard Emerald Raiya

Dubrovnik → Piraeus

Rare itinerary

from$20,640pp · cruise fare≈ $1,474/night pp

Fares checked nightly

Jul 2027Next 10 Jul 2027 · 1 more
Greece Intensive Cruise: Thessaloniki, Patmos & MykonosEurope

Azamara

10 nights: Piraeus & Mykonos, the Mediterranean

Aboard Azamara Onward

Round-trip from Piraeus

Overnight in ThessaloníkiRare itinerary

from$4,449pp · cruise fare≈ $445/night pp

Fares checked nightly

Apr 2027Next 14 Apr 2027
Istanbul → Piraeus (Athens)Mediterranean & Western Europe

Explora Journeys

7 nights: Istanbul & Mykonos

Aboard EXPLORA II

Istanbul → Piraeus

↓ $1,975 this monthAn Invitation to

from$5,925pp · cruise fare≈ $846/night pp

Fares checked nightly

May 2027Next 17 May 2027

Frequently asked

How many cruises to Pátmos does NestCruise have?
61 live sailings, 7 to 21 nights. A NestCruise advisor narrows them to the one that fits.
Which cruise lines visit Pátmos?
Azamara, Explora Journeys, Emerald Cruises and Seabourn, among others.
How long are cruises to Pátmos?
Most run 7 to 21 nights.
How much do cruises to Pátmos cost?
NestCruise doesn't publish fares — it's a quote-only concierge. Share your dates and party size and an advisor prices your exact sailing at no cost.