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Cruises to Izmir

39 live cruises call at Izmir — 5 to 33 nights, departing 10 ports, across 5 lines. A NestCruise advisor narrows them to the one that fits.

39 sailings
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Italy, Greece, TurkeyEurope

MSC Cruises

7 nights: Piraeus & Istanbul, the Mediterranean

Aboard MSC Orchestra

Round-trip from Bari

Open Jaw Cruise

from$185pp · cruise fare≈ $26/night pp

Fares checked nightly

Sails weekly, Oct 2026 – Jan 2028
Italy, Greece, TurkeyEurope

MSC Cruises

7 nights: Piraeus & Istanbul, the Mediterranean

Aboard MSC Lirica

Round-trip from Bari

Open Jaw Cruise

from$312pp · cruise fare≈ $45/night pp

Fares checked nightly

Sails weekly, Jan 2027 – Mar 2027
Greece, Turkey, Italy, CroatiaEurope

MSC Cruises

9 nights: Istanbul & Split, the Mediterranean

Aboard MSC Splendida

Round-trip from Piraeus

Cruise Only Obc

from$1,528pp · cruise fare≈ $170/night pp

Fares checked nightly

Sails every two weeks, Apr 2027 – Jul 2027
9-Day Greek Isles from Rome to Istanbul: Santorini, Athens & MaltaGreek Isles

Norwegian Cruise Line

9 nights: Santorini & Istanbul

Aboard Norwegian Viva

Civitavecchia → Istanbul

↓ $2,279 this monthRisk-free Cancellation

from$2,649pp · cruise fare≈ $294/night pp

Fares checked nightly

Jul 2027 – Aug 2027Next 2 Jul 2027 · 1 more
7-Night Greece & Dalmatian DelightsMEDITERRANEAN

Seabourn

7 nights: Mykonos & Istanbul, the Mediterranean

Aboard Seabourn Quest

Piraeus → Venice

Rare itinerary
Aug 2026Next 16 Aug 2026
Piraeus, Izmir, Istanbul, Corfu, Bari, Trieste, Katakolon, PiraeusEurope

MSC Cruises

9 nights: Piraeus & Istanbul, the Mediterranean

Aboard MSC Fantasia

Round-trip from Piraeus

Escape to SeaRare itinerary

from$1,411pp · cruise fare≈ $157/night pp

Fares checked nightly

Sep 2026Next 27 Sep 2026
Aegean & Adriatic TreasuresEurope

Oceania Cruises

7 nights: Istanbul & Kotor, the Mediterranean

Aboard Oceania Allura

Istanbul → Trieste

Rare itinerary
Sep 2026Next 26 Sep 2026
Greeks & ByzantinesEurope

Oceania Cruises

7 nights: Rhodes & Istanbul, the Mediterranean

Aboard Oceania Sonata

Piraeus → Istanbul

Overnight in IstanbulRare itinerary
Oct 2027Next 14 Oct 2027
Classical World UnfoldedEurope

Regent Seven Seas Cruises

9 nights: Istanbul & Rhodes, the Mediterranean

Aboard Seven Seas Explorer

Istanbul → Piraeus

↓ $13,299 this monthBonus Savings of

from$8,299pp · cruise fare≈ $922/night pp

Fares checked nightly

Sep 2028Next 24 Sep 2028
The Birth Of CivilizationEurope

Oceania Cruises

10 nights: Mykonos & Istanbul, the Mediterranean

Aboard Oceania Marina

Piraeus → Civitavecchia

Overnight in IstanbulRare itinerary
Nov 2027Next 17 Nov 2027
Turkish TreasuresEurope

Regent Seven Seas Cruises

10 nights: Istanbul & Mykonos, the Mediterranean

Aboard Seven Seas Voyager

Istanbul → Piraeus

Overnight in IstanbulRare itinerary
Nov 2026Next 27 Nov 2026
Across The AegeanEurope

Oceania Cruises

10 nights: Istanbul & Santorini, the Mediterranean

Aboard Oceania Vista

Istanbul → Piraeus

Rare itinerary
Mar 2028Next 21 Mar 2028
President's CruiseEurope

Regent Seven Seas Cruises

14 nights: Istanbul & Mykonos, the Mediterranean

Aboard Seven Seas Navigator

Istanbul → Civitavecchia

Overnight in AlexandriaRare itinerary
Oct 2026Next 2 Oct 2026
Mediterranean MosaicEurope

Oceania Cruises

14 nights: Istanbul & Santorini, the Mediterranean

Aboard Oceania Sirena

Istanbul → Civitavecchia

Overnight in IstanbulRare itinerary
Aug 2026Next 27 Aug 2026
Piraeus, Izmir, Istanbul, Corfu, Bari, PiraeusEurope

MSC Cruises

7 nights: Piraeus & Istanbul, the Mediterranean

Aboard MSC Orchestra

Round-trip from Piraeus

Open Jaw Cruise

from$185pp · cruise fare≈ $26/night pp

Fares checked nightly

Nov 2026 – Jan 2028Next 2 Nov 2026 · 50 more
Piraeus, Izmir, Istanbul, Corfu, Bari, PiraeusEurope

MSC Cruises

7 nights: Piraeus & Istanbul, the Mediterranean

Aboard MSC Lirica

Round-trip from Piraeus

Cruise Only Obc

from$453pp · cruise fare≈ $65/night pp

Fares checked nightly

Sails weekly, Jan 2027 – Mar 2027
Italy, Croatia, Greece, TurkeyEurope

MSC Cruises

9 nights: Split & Istanbul, the Mediterranean

Aboard MSC Splendida

Round-trip from Bari

Open Jaw Cruise

from$279pp · cruise fare≈ $31/night pp

Fares checked nightly

Apr 2027 – May 2027Next 21 Apr 2027 · 5 more
7-Night Greek Isles & EphesusMEDITERRANEAN

Seabourn

7 nights: Mykonos & Istanbul, the Mediterranean

Aboard Seabourn Quest

Round-trip from Piraeus

Rare itinerary
Oct 2026Next 11 Oct 2026
Trieste, Katakolon, Piraeus, Izmir, Istanbul, Corfu, Bari, TriesteEurope

MSC Cruises

9 nights: Piraeus & Istanbul, the Mediterranean

Aboard MSC Fantasia

Round-trip from Trieste

Escape to SeaRare itinerary

from$1,243pp · cruise fare≈ $138/night pp

Fares checked nightly

Sep 2026Next 24 Sep 2026
Crowning Ancient CulturesWorld Cruise

Oceania Cruises

36 nights: Barcelona & Mykonos

Aboard Oceania Sonata

Southampton → Istanbul

Overnight in BordeauxRare itinerary
Sep 2027Next 15 Sep 2027
Mediterranean UncoveredEurope

Regent Seven Seas Cruises

11 nights: Istanbul & Mykonos, the Mediterranean

Aboard Seven Seas Explorer

Istanbul → Fusina

↓ $17,599 this monthBonus Savings of

from$11,599pp · cruise fare≈ $1,054/night pp

Fares checked nightly

Jun 2028Next 19 Jun 2028
Isles & RivierasTransatlantic

Oceania Cruises

33 nights: Mykonos & Istanbul, the Atlantic crossing

Aboard Oceania Marina

Piraeus → Miami

Overnight in IstanbulRare itinerary
Nov 2027Next 17 Nov 2027
Season Of WonderEurope

Regent Seven Seas Cruises

14 nights: Istanbul & Piraeus, the Mediterranean

Aboard Seven Seas Voyager

Istanbul → Piraeus

Overnight in IstanbulRare itinerary
Dec 2028Next 14 Dec 2028
Arabia To The AdriaticAfrica

Oceania Cruises

38 nights: Istanbul & Santorini

Aboard Oceania Vista

Dubai → Civitavecchia

Overnight in Suez Canal TransitRare itinerary
Mar 2028Next 2 Mar 2028
Istanbul, Corfu, Bari, Piraeus, Izmir, IstanbulEurope

MSC Cruises

7 nights: Istanbul & Corfu, the Mediterranean

Aboard MSC Orchestra

Round-trip from Istanbul

Open Jaw Cruise

from$185pp · cruise fare≈ $26/night pp

Fares checked nightly

Nov 2026 – Jan 2028Next 4 Nov 2026 · 25 more
Istanbul, Corfu, Bari, Piraeus, Izmir, IstanbulEurope

MSC Cruises

7 nights: Istanbul & Corfu, the Mediterranean

Aboard MSC Lirica

Round-trip from Istanbul

Cruise Only Obc

from$453pp · cruise fare≈ $65/night pp

Fares checked nightly

Sails weekly, Jan 2027 – Mar 2027
Italy, Croatia, Greece, TurkeyEurope

MSC Cruises

5 nights: Split & Istanbul, the Mediterranean

Aboard MSC Splendida

Trieste → Istanbul

Open Jaw CruiseRare itinerary

from$279pp · cruise fare≈ $56/night pp

Fares checked nightly

Apr 2027Next 22 Apr 2027
7-Night Turkey & Greek Isle GemsMEDITERRANEAN

Seabourn

7 nights: Istanbul & Rhodes, the Mediterranean

Aboard Seabourn Quest

Istanbul → Piraeus

NxRare itinerary

from$14,798pp · cruise fare≈ $2,114/night pp

Fares checked nightly

Oct 2026Next 18 Oct 2026
Cradles Of HistoryEurope

Regent Seven Seas Cruises

18 nights: Istanbul & Dubrovnik, the Mediterranean

Aboard Seven Seas Explorer

Istanbul → Civitavecchia

↓ $13,299 this monthBonus Savings of

from$8,299pp · cruise fare≈ $461/night pp

Fares checked nightly

Sep 2028Next 24 Sep 2028
Emirates & EmpiresAfrica

Oceania Cruises

55 nights: Istanbul & Santorini

Aboard Oceania Vista

Singapore → Civitavecchia

Overnight in Port KlangRare itinerary
Feb 2028Next 14 Feb 2028
Izmir, Istanbul, Corfu, Bari, Piraeus, IzmirEurope

MSC Cruises

7 nights: Istanbul & Corfu, the Mediterranean

Aboard MSC Orchestra

Round-trip from Izmir

Open Jaw Cruise

from$185pp · cruise fare≈ $26/night pp

Fares checked nightly

Nov 2026 – Nov 2027Next 24 Nov 2026 · 5 more
Bari, Piraeus, Izmir, IstanbulEurope

MSC Cruises

4 nights: Piraeus & Istanbul, the Mediterranean

Aboard MSC Lirica

Bari → Istanbul

Open Jaw CruiseRare itinerary

from$312pp · cruise fare≈ $78/night pp

Fares checked nightly

Jan 2027Next 9 Jan 2027
Italy, Croatia, Greece, TurkeyEurope

MSC Cruises

8 nights: Split & Istanbul, the Mediterranean

Aboard MSC Splendida

Trieste → Bari

Open Jaw CruiseRare itinerary

from$279pp · cruise fare≈ $35/night pp

Fares checked nightly

Apr 2027Next 22 Apr 2027
Through The AgesEurope

Regent Seven Seas Cruises

20 nights: Istanbul & Mykonos, the Mediterranean

Aboard Seven Seas Explorer

Piraeus → Fusina

↓ $14,299 this monthBonus Savings of

from$9,299pp · cruise fare≈ $465/night pp

Fares checked nightly

Jun 2028Next 10 Jun 2028
The Best Of East & WestPacific

Oceania Cruises

96 nights: Istanbul & Santorini, Australia & New Zealand

Aboard Oceania Vista

Auckland → Civitavecchia

Overnight in BaliRare itinerary
Jan 2028Next 4 Jan 2028
Italy, Greece, TurkeyEurope

MSC Cruises

4 nights: Piraeus & Istanbul, the Mediterranean

Aboard MSC Orchestra

Bari → Istanbul

Open Jaw CruiseRare itinerary

from$185pp · cruise fare≈ $46/night pp

Fares checked nightly

Oct 2026 – Oct 2027Next 31 Oct 2026 · 2 more
Piraeus, Izmir, Istanbul, Corfu, BariEurope

MSC Cruises

5 nights: Piraeus & Istanbul, the Mediterranean

Aboard MSC Lirica

Piraeus → Bari

Open Jaw CruiseRare itinerary

from$519pp · cruise fare≈ $104/night pp

Fares checked nightly

Mar 2027Next 8 Mar 2027
Greece, Turkey, ItalyEurope

MSC Cruises

5 nights: Piraeus & Istanbul, the Mediterranean

Aboard MSC Orchestra

Piraeus → Bari

Open Jaw CruiseRare itinerary

from$185pp · cruise fare≈ $37/night pp

Fares checked nightly

Jan 2027 – Apr 2027Next 4 Jan 2027 · 1 more
Piraeus, Izmir, Istanbul, Corfu, Bari, Santorini, PiraeusEurope

MSC Cruises

8 nights: Istanbul & Santorini, the Mediterranean

Aboard MSC Orchestra

Round-trip from Piraeus

Cruise Only ObcRare itinerary

from$956pp · cruise fare≈ $120/night pp

Fares checked nightly

Apr 2027Next 19 Apr 2027

Frequently asked

How many cruises to Izmir does NestCruise have?
39 live sailings, 5 to 33 nights. A NestCruise advisor narrows them to the one that fits.
Which cruise lines visit Izmir?
MSC Cruises, Oceania Cruises, Regent Seven Seas Cruises and Seabourn, among others.
How long are cruises to Izmir?
Most run 5 to 33 nights.
How much do cruises to Izmir cost?
NestCruise doesn't publish fares — it's a quote-only concierge. Share your dates and party size and an advisor prices your exact sailing at no cost.