Cruises to Grand Cayman
52 live cruises call at Grand Cayman — 6 to 21 nights, departing 6 ports, across 2 lines. A NestCruise advisor narrows them to the one that fits.
CaribbeanCarnival Cruise Line
6-Day Western Caribbean
Aboard Carnival Horizon
Miami, Florida → At Sea → Grand Cayman → Ocho Rios +1 more
6 nights · 5 departures
Balanced · 5 ports
CaribbeanCarnival Cruise Line
6-Day Western Caribbean
Aboard Carnival Venezia
Miami, Florida → Celebration Key → At Sea → Ocho Rios +1 more
6 nights · 6 departures
Balanced · 5 ports
CaribbeanCarnival Cruise Line
7-Day Western Caribbean
Aboard Carnival Legend
Tampa, Florida → At Sea → Cozumel → Montego Bay +1 more
7 nights · 6 departures
Balanced · 5 ports
CaribbeanHolland America Line
10-Day Western Caribbean: Greater Antilles, Belize & Mexico
Aboard Rotterdam
Fort Lauderdale, Florida → Half Moon Cay → Falmouth → Grand Cayman +3 more
10 nights · 6 departures
Balanced · 7 ports
AmericasHolland America Line
12-Day Panama Canal Discovery: Costa Rica & Greater Antilles
Aboard Nieuw Amsterdam
Fort Lauderdale, Florida → Half Moon Cay → Aruba → Cartagena +5 more
12 nights · 6 departures
Balanced · 9 ports
CaribbeanCarnival Cruise Line
8-Day Caribbean & Panama
Aboard Carnival Spirit
Tampa, Florida → At Sea → Puerto Limón → Colón +1 more
8 nights · 5 departures
Balanced · 5 ports
CaribbeanCarnival Cruise Line
10-Day Western Caribbean
Aboard Carnival Miracle
Galveston, Texas → At Sea → Grand Cayman → Montego Bay +3 more
10 nights · 5 departures
Balanced · 7 ports
AmericasHolland America Line
12-Day Panama Canal Discovery: Costa Rica & Greater Antilles
Aboard Oosterdam
Fort Lauderdale, Florida → Half Moon Cay → Aruba → Cartagena +5 more
12 nights · 5 departures
Balanced · 9 ports
CaribbeanCarnival Cruise Line
6-Day Western Caribbean
Aboard Carnival Magic
Miami, Florida → Celebration Key → At Sea → Montego Bay +1 more
6 nights · 3 departures
Balanced · 5 ports
CaribbeanCarnival Cruise Line
10-Day Western Caribbean
Aboard Carnival Sunshine
Galveston, Texas → At Sea → Grand Cayman → Montego Bay +3 more
10 nights · 3 departures
Balanced · 7 ports
CaribbeanCarnival Cruise Line
6-Day Western Caribbean
Aboard Carnival Firenze
Miami, Florida → Celebration Key → At Sea → Montego Bay +1 more
6 nights · 2 departures
Balanced · 5 ports
CaribbeanCarnival Cruise Line
6-Day Western Caribbean
Aboard Carnival Sunrise
Miami, Florida → At Sea → Grand Cayman → Ocho Rios +1 more
6 nights · 2 departures
Balanced · 5 ports
CaribbeanHolland America Line
7-Day Western Caribbean: Greater Antilles & Mexico
Aboard Eurodam
Fort Lauderdale, Florida → Half Moon Cay → Ocho Rios → Grand Cayman +1 more
7 nights · 2 departures
Balanced · 5 ports
CaribbeanHolland America Line
7-Day Western Caribbean: Greater Antilles & Mexico
Aboard Zuiderdam
Miami, Florida → Key West, Florida → Ocho Rios → Grand Cayman +1 more
7 nights · 2 departures
Balanced · 5 ports
CaribbeanHolland America Line
14-Day Western & Eastern Caribbean: Mexico & Bahamas
Aboard Nieuw Statendam
Fort Lauderdale, Florida → Half Moon Cay → Ocho Rios → Grand Cayman +4 more
14 nights · 2 departures
Balanced · 8 ports
CaribbeanCarnival Cruise Line
8-Day Western Caribbean
Aboard Carnival Breeze
Galveston, Texas → At Sea → Montego Bay → Grand Cayman +1 more
8 nights · 1 departure
Balanced · 5 ports
CaribbeanCarnival Cruise Line
8-Day Western Caribbean
Aboard Carnival Dream
Galveston, Texas → At Sea → Cozumel → Grand Cayman +1 more
8 nights · 1 departure
Balanced · 5 ports
AmericasHolland America Line
41-Day Grand South America & Antarctica Voyage
Aboard Zaandam
Fort Lauderdale, Florida → Grand Cayman → Fuerte Amador → Manta +18 more
41 nights · 1 departure
Balanced · 22 ports
CaribbeanCarnival Cruise Line
8-Day Western Caribbean
Aboard Carnival Horizon
Galveston, Texas → At Sea → Montego Bay → Grand Cayman +1 more
8 nights · 1 departure
Balanced · 5 ports
CaribbeanCarnival Cruise Line
8-Day Western Caribbean
Aboard Carnival Legend
Tampa, Florida → At Sea → Grand Cayman → Roatán Island +2 more
8 nights · 3 departures
Balanced · 6 ports
CaribbeanHolland America Line
21-Day Western & Eastern Caribbean: Mexico & Leeward Islands
Aboard Rotterdam
Fort Lauderdale, Florida → Half Moon Cay → Falmouth → Grand Cayman +9 more
21 nights · 6 departures
Balanced · 13 ports
CaribbeanHolland America Line
21-Day Panama Canal & Southern Caribbean: Abc Islands
Aboard Nieuw Amsterdam
Fort Lauderdale, Florida → Half Moon Cay → Aruba → Cartagena +7 more
21 nights · 3 departures
Balanced · 11 ports
CaribbeanCarnival Cruise Line
8-Day Western Caribbean
Aboard Carnival Spirit
Tampa, Florida → At Sea → Grand Cayman → Roatán Island +2 more
8 nights · 1 departure
Balanced · 6 ports
CaribbeanHolland America Line
21-Day Southern Caribbean & Panama Canal: Abc Islands
Aboard Oosterdam
Fort Lauderdale, Florida → Bonaire → Curaçao → Aruba +7 more
21 nights · 4 departures
Balanced · 11 ports
CaribbeanCarnival Cruise Line
8-Day Western Caribbean
Aboard Carnival Firenze
Port Canaveral, Florida → At Sea → Grand Cayman → Montego Bay +1 more
8 nights · 1 departure
Balanced · 5 ports
CaribbeanHolland America Line
14-Day Western & Eastern Caribbean: Mexico & Bahamas
Aboard Eurodam
Fort Lauderdale, Florida → Half Moon Cay → Ocho Rios → Grand Cayman +4 more
14 nights · 2 departures
Balanced · 8 ports
CaribbeanHolland America Line
14-Day Western & Eastern Caribbean: Mexico & Bahamas Holiday
Aboard Zuiderdam
Miami, Florida → Half Moon Cay → Ocho Rios → Grand Cayman +4 more
14 nights · 1 departure
Balanced · 8 ports
CaribbeanHolland America Line
14-Day Eastern & Western Caribbean: San Juan & Mexico
Aboard Nieuw Statendam
Fort Lauderdale, Florida → Grand Turk Island → San Juan (Puerto Rico) → Saint Thomas +4 more
14 nights · 2 departures
Balanced · 8 ports
AmericasHolland America Line
70-Day Grand South America & Antarctica Voyage
Aboard Zaandam
Fort Lauderdale, Florida → Grand Cayman → Fuerte Amador → Manta +30 more
70 nights · 1 departure
Balanced · 34 ports
CaribbeanCarnival Cruise Line
8-Day Caribbean & Panama
Aboard Carnival Legend
Tampa, Florida → At Sea → Puerto Limón → Colón +1 more
8 nights · 2 departures
Balanced · 5 ports
CaribbeanHolland America Line
21-Day Western & Eastern Caribbean Holiday: Belize & Mexico
Aboard Rotterdam
Fort Lauderdale, Florida → Half Moon Cay → Falmouth → Grand Cayman +9 more
21 nights · 1 departure
Balanced · 13 ports
CaribbeanHolland America Line
21-Day Eastern Caribbean & Panama Canal: U.s. Virgin Islands
Aboard Nieuw Amsterdam
Fort Lauderdale, Florida → Antigua → Saint Thomas → Tortola +9 more
21 nights · 2 departures
Balanced · 13 ports
CaribbeanCarnival Cruise Line
9-Day Carnival Journeys Western Caribbea
Aboard Carnival Spirit
Mobile, Alabama → At Sea → Cozumel → Roatán Island +2 more
9 nights · 1 departure
Balanced · 6 ports
CaribbeanHolland America Line
21-Day Panama Canal & Southern Caribbean: Abc Islands
Aboard Oosterdam
Fort Lauderdale, Florida → Half Moon Cay → Aruba → Cartagena +7 more
21 nights · 4 departures
Balanced · 11 ports
CaribbeanHolland America Line
14-Day Western & Eastern Caribbean: Mexico & Bahamas Holiday
Aboard Eurodam
Fort Lauderdale, Florida → Half Moon Cay → Ocho Rios → Grand Cayman +4 more
14 nights · 1 departure
Balanced · 8 ports
CaribbeanHolland America Line
14-Day Eastern & Western Caribbean: San Juan & Mexico
Aboard Zuiderdam
Miami, Florida → Grand Turk Island → San Juan (Puerto Rico) → Saint Thomas +4 more
14 nights · 1 departure
Balanced · 8 ports
CaribbeanHolland America Line
7-Day Western Caribbean Holiday: Greater Antilles
Aboard Nieuw Statendam
Fort Lauderdale, Florida → Half Moon Cay → Ocho Rios → Grand Cayman +1 more
7 nights · 1 departure
Balanced · 5 ports
CaribbeanCarnival Cruise Line
5-Day Western Caribbean
Aboard Carnival Legend
Tampa, Florida → At Sea → Grand Cayman → Cozumel
5 nights · 1 departure
Balanced · 4 ports
CaribbeanHolland America Line
21-Day Eastern & Western Caribbean Holiday: Belize & Mexico
Aboard Rotterdam
Fort Lauderdale, Florida → Sint Maarten → Basseterre, Saint Kitts → Roseau +9 more
21 nights · 1 departure
Balanced · 13 ports
CaribbeanHolland America Line
21-Day Panama Canal & Eastern Caribbean: U.s. Virgin Islands
Aboard Nieuw Amsterdam
Fort Lauderdale, Florida → Half Moon Cay → Aruba → Cartagena +9 more
21 nights · 2 departures
Balanced · 13 ports
CaribbeanCarnival Cruise Line
10-Day Western Caribbean
Aboard Carnival Spirit
Galveston, Texas → At Sea → Grand Cayman → Montego Bay +3 more
10 nights · 1 departure
Balanced · 7 ports
AmericasHolland America Line
16-Day Inca & Panama Canal Discovery: Lima Overnight
Aboard Oosterdam
Fort Lauderdale, Florida → Grand Cayman → Fuerte Amador → Manta +5 more
16 nights · 2 departures
Balanced · 9 ports
CaribbeanHolland America Line
14-Day Eastern & Western Caribbean: San Juan & Mexico
Aboard Eurodam
Fort Lauderdale, Florida → Grand Turk Island → San Juan (Puerto Rico) → Saint Thomas +4 more
14 nights · 1 departure
Balanced · 8 ports
CaribbeanHolland America Line
14-Day Western & Eastern Caribbean: Mexico & Bahamas
Aboard Zuiderdam
Miami, Florida → Key West, Florida → Ocho Rios → Grand Cayman +5 more
14 nights · 1 departure
Balanced · 9 ports
CaribbeanHolland America Line
14-Day Western & Eastern Caribbean Holiday: Mexico & Bahamas
Aboard Nieuw Statendam
Fort Lauderdale, Florida → Half Moon Cay → Ocho Rios → Grand Cayman +4 more
14 nights · 1 departure
Balanced · 8 ports
CaribbeanCarnival Cruise Line
Journeys - 13-Day Caribbean & Panama
Aboard Carnival Legend
Tampa, Florida → At Sea → Grand Cayman → Puerto Limón +4 more
13 nights · 1 departure
Balanced · 8 ports
Frequently asked
- How many cruises to Grand Cayman does NestCruise have?
- 52 live sailings, 6 to 21 nights. A NestCruise advisor narrows them to the one that fits.
- Which cruise lines visit Grand Cayman?
- Holland America Line and Carnival Cruise Line, among others.
- How long are cruises to Grand Cayman?
- Most run 6 to 21 nights.
- How much do cruises to Grand Cayman cost?
- NestCruise doesn't publish fares — it's a quote-only concierge. Share your dates and party size and an advisor prices your exact sailing at no cost.