Cruise itinerary
21-Night Mediterranean Cruise from Barcelona
21 nights · Mediterranean · 14 ports of call
21-night Mediterranean cruise aboard Sun Princess, departing Barcelona and calling at Marseille, Genoa, Civitavecchia-Rome, Naples, Bar Montenegro and Corfu Island and 7 more.
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- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Sun Princess
- Cruise line
- Princess Cruises
- Duration
- 21 nights
- Region
- Mediterranean
- Departs
- Barcelona
- Returns
- Istanbul
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Sun Princess sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1
Barcelona
Depart 17:00
Catalonia's seafront capital and one of the Mediterranean's busiest cruise homeports. Gaudí's Sagrada Família and Park Güell crown the city, while the tree-lined Ramblas and the Gothic Quarter's medieval lanes lie a short ride from the terminal.
- Sagrada Família
- La Rambla
- Gothic Quarter
- Day2
Marseille
Arrive 08:00 · Depart 17:00
France's oldest city and biggest Mediterranean port, set around the old harbour of the Vieux-Port. The hilltop basilica of Notre-Dame de la Garde watches over the bay, with the Calanques inlets and bouillabaisse stalls a short way off.
- Vieux-Port
- Notre-Dame de la Garde
- Calanques
- Day3
Genoa
Arrive 08:00 · Depart 18:00
Italy's great maritime city, stacked up the Ligurian hills above one of the Mediterranean's busiest harbours. Its old town is a maze of tall, narrow caruggi, and it claims pesto and focaccia as local inventions; the Aquarium and Renaissance palaces of Via Garibaldi sit close to the port.
- Old-town caruggi
- Genoa Aquarium
- Via Garibaldi palaces
- Day4
Civitavecchia-Rome
Arrive 07:00 · Depart 19:00
The deep-water port serving Rome, roughly 80 kilometres up the coast. Ships dock here for shore excursions to the Colosseum, the Vatican and the Roman Forum, while the town itself keeps a working harbour and a Michelangelo-designed fortress.
- Gateway to Rome
- Fort Michelangelo
- Vatican excursions
- Day5
Naples
Arrive 07:00 · Depart 19:00
A southern Italian port on its namesake bay, in the shadow of Mount Vesuvius. Ships dock near the historic centre, the gateway to Pompeii, the cliffs of the Amalfi Coast and the island of Capri, in a city that claims to have invented pizza.
- Mount Vesuvius
- Pompeii
- Gateway to Capri
- Day6At sea
- Day7
Bar Montenegro
Arrive 07:30 · Depart 18:00
- Day8
Corfu Island
Arrive 09:00 · Depart 19:00
An Ionian island off Greece's northwest coast, greener and more Venetian-feeling than the Aegean isles. Ships call at its old town, a UNESCO-listed warren of Italianate streets between two hilltop fortresses, with pebbly coves around the shore.
- Old Fortress
- Liston arcade
- Ionian coves
- Day9At sea
- Day10
Souda-Chania
Arrive 07:00 · Depart 18:00
The port of Chania on the northwest coast of Crete, set beside Souda Bay, one of the Mediterranean's deepest natural harbours. It opens onto the old Venetian quarter of Chania, with its lighthouse, harbour-front, and lanes of the former Turkish town.
- Chania old town
- Venetian lighthouse
- Souda Bay
- Day11
Mykonos Island
Arrive 07:00 · Depart 21:00
A Cycladic island in the Aegean known for whitewashed houses and a lively summer scene. Ships anchor off the main town, where windmills overlook the sea, the Little Venice quarter meets the waves and sandy beaches stretch along the south coast.
- Windmills
- Little Venice
- Chora town
- Day12
Piraeus-Athens
Arrive 06:00 · Depart 19:00
The ancient harbour of Athens and Greece's principal cruise port. Ferries fan out to the Aegean islands from its quays, while the Acropolis, the Plaka district and the National Archaeological Museum sit a short metro ride inland.
- Gateway to Athens
- Acropolis
- Aegean ferries
- Day13At sea
- Day14
Bar Montenegro
Arrive 07:30 · Depart 18:00
- Day15
Corfu Island
Arrive 08:00 · Depart 17:00
An Ionian island off Greece's northwest coast, greener and more Venetian-feeling than the Aegean isles. Ships call at its old town, a UNESCO-listed warren of Italianate streets between two hilltop fortresses, with pebbly coves around the shore.
- Old Fortress
- Liston arcade
- Ionian coves
- Day16
Messina
Arrive 09:00 · Depart 19:00
A Sicilian port on the strait that separates the island from mainland Italy, framed by the Peloritani mountains. Its harbour clock tower performs an elaborate noon display, and the town is a common gateway to Taormina and the slopes of Mount Etna.
- Etna day trips
- Taormina gateway
- Astronomical clock
- Day17At sea
- Day18
Santorini Island
Arrive 07:00 · Depart 21:00
The crescent rim of a flooded volcanic caldera in the Greek Cyclades, its whitewashed villages strung along cliffs high above the sea. Fira and Oia draw crowds for sunset views, while the caldera's dark beaches and the ancient site of Akrotiri lie below.
- Oia sunset
- Fira town
- Caldera cliffs
- Day19
Mykonos Island
Arrive 08:00 · Depart 21:00
A Cycladic island in the Aegean known for whitewashed houses and a lively summer scene. Ships anchor off the main town, where windmills overlook the sea, the Little Venice quarter meets the waves and sandy beaches stretch along the south coast.
- Windmills
- Little Venice
- Chora town
- Day20
Kusadasi
Arrive 07:00 · Depart 16:00
A resort town on Turkey's Aegean coast that serves as the cruise gateway to ancient Ephesus, one of the best-preserved classical cities in the Mediterranean. Pigeon Island guards the harbour, and the marble Library of Celsus lies a short drive inland.
- Ephesus ruins
- Library of Celsus
- Pigeon Island
- Day21
Istanbul
Arrive 13:00 · Depart 13:00
The city straddling Europe and Asia along the Bosphorus, once Byzantium and then Constantinople. Ships dock near the historic peninsula, within reach of the Hagia Sophia, the Blue Mosque and the covered Grand Bazaar's labyrinth of stalls.
- Hagia Sophia
- Blue Mosque
- Grand Bazaar
- Day22
Istanbul
The city straddling Europe and Asia along the Bosphorus, once Byzantium and then Constantinople. Ships dock near the historic peninsula, within reach of the Hagia Sophia, the Blue Mosque and the covered Grand Bazaar's labyrinth of stalls.
- Hagia Sophia
- Blue Mosque
- Grand Bazaar
Upcoming departures
- 13 Jun 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
21-Night Mediterranean Cruise from Barcelona FAQ
Which ports does this cruise visit?
This 21-night Mediterranean cruise calls at Barcelona, Marseille, Genoa, Civitavecchia-Rome, Naples, Bar Montenegro, Corfu Island, Souda-Chania, Mykonos Island, Piraeus-Athens, Messina, Santorini Island, Kusadasi and Istanbul.
How many days are spent at sea?
4 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Barcelona and ends in Istanbul.
How long is this cruise?
21 nights aboard Sun Princess.
When does this itinerary sail?
Upcoming departures include 13 Jun 2027. A NestCruise advisor can confirm current availability.